Antimicrobial peptides derived from growth factors

Growth Factors

Volumn 25, Issue 1, 2007, Pages 60-70

  Malmsten, Martin ^a   Davoudi, Mina ^b   Walse, Björn ^c   Rydengård, Victoria ^b   Pasupuleti, Mukesh ^b   Mörgelin, Matthias ^b   Schmidtchen, Artur ^b  

^a UPPSALA UNIVERSITY   (Sweden)

^b LUND UNIVERSITY   (Sweden)

^c SARomics AB   (Sweden)

Author keywords

Antimicrobial; Growth factors; Heparin; Liposome

Indexed keywords

AMPHIREGULIN; ANTIBIOTIC AGENT; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; FIBROBLAST GROWTH FACTOR; GROWTH FACTOR; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; LIPOSOME; PEPTIDE GKR22; PEPTIDE GRP19; PEPTIDE LKI24; PEPTIDE LKK21; PEPTIDE LKR21; PEPTIDE LNG21; PEPTIDE LNQ21; PEPTIDE LRP24; PEPTIDE PKR21; PEPTIDE QRA21; PEPTIDE RVR21; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR B; POLYPEPTIDE ANTIBIOTIC AGENT; SCATTER FACTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BACTERIAL COUNT; BACTERIAL VIABILITY; BACTERIUM ISOLATE; CANDIDA ALBICANS; CONTROLLED STUDY; DRUG DESIGN; ESCHERICHIA COLI; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HEMOLYSIS; MEMBRANE DAMAGE; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; TISSUE REPAIR; TRANSMISSION ELECTRON MICROSCOPY;

AMINO ACID SEQUENCE; ANTIMICROBIAL CATIONIC PEPTIDES; BACILLUS SUBTILIS; BACTERIA; CANDIDA ALBICANS; EPIDERMAL GROWTH FACTOR; ESCHERICHIA COLI; GROWTH SUBSTANCES; HUMANS; MICROBIAL SENSITIVITY TESTS; MICROSCOPY, ELECTRON; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

BACILLUS SUBTILIS; CANDIDA ALBICANS; ESCHERICHIA COLI; FUNGI; NEGIBACTERIA; POSIBACTERIA; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

EID: 34247627920     PISSN: 08977194     EISSN: 10292292     Source Type: Journal    
DOI: 10.1080/08977190701344120     Document Type: Article

References (45)

1. Andersson, E., Rydengard, V., Sonesson, A., Morgelin, M., Bjorck, L. and Schmidtchen, A. (2004) Antimicrobial activities of heparin-binding peptides. Eur J Biochem, 271, pp. 1219-1226.
2. Beisswenger, C. and Bals, R. (2005) Functions of antimicrobial peptides in host defense and immunity. Curr Protein Pept Sci, 6, pp. 255-264.
3. Blondelle, SE and Lohner, K. (2000) Combinatorial libraries: A tool to design antimicrobial and antifungal peptide analogues having lytic specificities for structure-activity relationship studies. Biopolymers, 55, pp. 74-87.
4. Brogden, KA (2005) Antimicrobial peptides: Pore formers or metabolic inhibitors in bacteria?. Nat Rev Microbiol, 3, pp. 238-250.
5. Brown, KL and Hancock, RE (2006) Cationic host defense (antimicrobial) peptides. Curr Opin Immunol, 18, pp. 24-30.
6. Bulet, P., Stocklin, R. and Menin, L. (2004) Anti-microbial peptides: From invertebrates to vertebrates. Immunol Rev, 198, pp. 169-184.
7. Cardin, AD and Weintraub, HJ (1989) Molecular modeling of protein-glycosaminoglycan interactions. Arteriosclerosis, 9, pp. 21-32.
8. Cribbs, RK, Luquette, MH and Besner, GE (1998) Acceleration of partial-thickness burn wound healing with topical application of heparin-binding EGF-like growth factor (HB-EGF). J Burn Care Rehabil, 19, pp. 95-101.
9. de Coupade, C., Fittipaldi, A., Chagnas, V., Michel, M., Carlier, S., Tasciotti, E., Darmon, A., Ravel, D., Kearsey, J., Giacca, M. and Cailler, F. (2005) Novel human-derived cell-penetrating peptides for specific subcellular delivery of therapeutic biomolecules. Biochem J, 390, pp. 407-418.
10. Durr, UH, Sudheendra, US and Ramamoorthy, A. (2006) LL-37, the only human member of the cathelicidin family of antimicrobial peptides. Biochim Biophys Acta, 1758, pp. 1408-1425.
11. Elsbach, P. (2003) What is the real role of antimicrobial polypeptides that can mediate several other inflammatory responses?. J Clin Invest, 111, pp. 1643-1645.
12. Fager, G., Camejo, G. and Bondjers, G. (1992) Heparin-like glycosaminoglycans influence growth and phenotype of human arterial smooth muscle cells in vitro I. Evidence for reversible binding and inactivation of the platelet-derived growth factor by heparin. In Vitro Cell Dev Biol, 28, pp. 168-175.
13. Fernandez-Lopez, S., Kim, HS, Choi, EC, Delgado, M., Granja, JR, Khasanov, A., Kraehenbuehl, K., Long, G., Weinberger, DA, Wilcoxen, KM and Ghadiri, MR (2001) Antibacterial agents based on the cyclic, -alpha-peptide architecture. Nature, 412, pp. 452-455.
14. Frick, IM, Akesson, P., Herwald, H., Morgelin, M., Malmsten, M., Nagler, DK and Bjorck, L. (2006) The contact system - a novel branch of innate immunity generating antibacterial peptides. Embo J, 25, pp. 5569-5578.
15. Ganz, T. (2001) Antimicrobial proteins and peptides in host defense. Semin Respir Infect, 16, pp. 4-10.
16. Heilborn, JD, Nilsson, MF, Kratz, G., Weber, G., Sorensen, O., Borregaard, N. and Stahle-Backdahl, M. (2003) The cathelicidin anti-microbial peptide LL-37 is involved in re-epithelialization of human skin wounds and is lacking in chronic ulcer epithelium. J Invest Dermatol, 120, pp. 379-389.
17. Keswani, SG, Katz, AB, Lim, FY, Zoltick, P., Radu, A., Alaee, D., Herlyn, M. and Crombleholme, TM (2004) Adenoviral mediated gene transfer of PDGF-B enhances wound healing in type I and type II diabetic wounds. Wound Repair Regen, 12, pp. 497-504.
18. Lehrer, RI, Rosenman, M., Harwig, SS, Jackson, R. and Eisenhauer, P. (1991) Ultrasensitive assays for endogenous antimicrobial polypeptides. J Immunol Methods, 137, pp. 167-173.
19. Post, M., Volk, R., Gao, Y., Metais, C., Sato, K., Tsai, J., Aird, W., Rosenberg, RD, Hampton, TG, Sellke, F., Carmeliet, P. and Simons, M. (2000) PR39, a peptide regulator of angiogenesis. Nat Med, 6, pp. 49-55.
20. Linding, R., Russell, RB, Neduva, V. and Gibson, TJ (2003) GlobPlot: Exploring protein sequences for globularity and disorder. Nucleic Acids Res, 31, pp. 3701-3708.
21. Lohner, K. and Blondelle, SE (2005) Molecular mechanisms of membrane perturbation by antimicrobial peptides and the use of biophysical studies in the design of novel peptide antibiotics. Comb Chem High Throughput Screen, 8, pp. 241-256.
22. Louie, GV, Yang, W., Bowman, ME and Choe, S. (1997) Crystal structure of the complex of diphtheria toxin with an extracellular fragment of its receptor. Mol Cell, 1, pp. 67-78.
23. Makovitzki, A., Avrahami, D. and Shai, Y. (2006) Ultrashort antibacterial and antifungal lipopeptides. Proc Natl Acad Sci USA, 103, pp. 15997-16002.
24. Malina, A. and Shai, Y. (2005) Conjugation of fatty acids with different lengths modulates the antibacterial and antifungal activity of a cationic biologically inactive peptide. Biochem J, 390, pp. 695-702.
25. Mangoni, ML, Papo, N., Barra, D., Simmaco, M., Bozzi, A., Giulio, A Di and Rinaldi, AC (2004) Effects of the antimicrobial peptide temporin L on cell morphology, membrane permeability and viability of Escherichia coli. Biochem J, 380, pp. 859-865.
26. Marikovsky, M., Breuing, K., Liu, PY, Eriksson, E., Higashiyama, S., Farber, P., Abraham, J. and Klagsbrun, M. (1993) Appearance of heparin-binding EGF-like growth factor in wound fluid as a response to injury. Proc Natl Acad Sci USA, 90, pp. 3889-3893.
27. Nordahl, EA, Rydengard, V., Morgelin, M. and Schmidtchen, A. (2005) Domain 5 of high molecular weight kininogen is antibacterial. J Biol Chem, 280, pp. 34832-34839.
28. Nordahl, EA, Rydengard, V., Nyberg, P., Nitsche, DP, Morgelin, M., Malmsten, M., Bjorck, L. and Schmidtchen, A. (2004) Activation of the complement system generates antibacterial peptides. Proc Natl Acad Sci USA, 101, pp. 16879-16884.
29. Pasupuleti, M., Walse, B., Nordahl, EA, Morgelin, M., Malmsten, M. and Schmidtchen, A. (2006) Preservation of antimicrobial properties of complement peptide C3a - from invertebrates to humans. J Biol Chem, 282, pp. 2520-2528.
30. Powers, JP and Hancock, RE (2003) The relationship between peptide structure and antibacterial activity. Peptides, 24, pp. 1681-1691.
31. Raman, R., Venkataraman, G., Ernst, S., Sasisekharan, V. and Sasisekharan, R. (2003) Structural specificity of heparin binding in the fibroblast growth factor family of proteins. Proc Natl Acad Sci USA, 100, pp. 2357-2362.
32. Ringstad, L., Kacprzyk, L., Schmidtchen, A. and Malmsten, M. (2006) Effects of topology, length, and charge on the activity of a kininogen-derived peptide on lipid membranes and bacteria. Biochim Biophys Acta, 1768, pp. 715-727.
33. Ringstad, L., Schmidtchen, A. and Malmsten, M. (2006) Effect of peptide length on the interaction between consensus peptides and DOPC/DOPA bilayers. Langmuir, 22, pp. 5042-5050.
34. Sajjan, US, Tran, LT, Sole, N., Rovaldi, C., Akiyama, A., Friden, PM, Forstner, JF and Rothstein, DM (2001) P-113D, an antimicrobial peptide active against Pseudomonas aeruginosa, retains activity in the presence of sputum from cystic fibrosis patients. Antimicrob Agents Chemother, 45, pp. 3437-3444.
35. Schilling, D., Reid, IJ, Hujer, A., Morgan, D., Demoll, E., Bummer, P., Fenstermaker, RA and Kaetzel, DM (1998) Loop III region of platelet-derived growth factor (PDGF) B-chain mediates binding to PDGF receptors and heparin. Biochem J, 333, pp. 637-644.
36. Sorensen, OE, Thapa, DR, Roupe, KM, Valore, EV, Sjobring, U., Roberts, AA, Schmidtchen, A. and Ganz, T. (2006) Injury-induced innate immune response in human skin mediated by transactivation of the epidermal growth factor receptor. J Clin Invest, 116, pp. 1878-1885.
37. Thompson, SA, Higashiyama, S., Wood, K., Pollitt, NS, Damm, D., McEnroe, G., Garrick, B., Ashton, N., Lau, K. and Hancock, N. (1994) Characterization of sequences within heparin-binding EGF-like growth factor that mediate interaction with heparin. J Biol Chem, 269, pp. 2541-2549.
38. Tossi, A. and Sandri, L. (2002) Molecular diversity in gene-encoded, cationic antimicrobial polypeptides. Curr Pharm Des, 8, pp. 743-761.
39. Tossi, A., Sandri, L. and Giangaspero, A. (2000) Amphipathic, alpha-helical antimicrobial peptides. Biopolymers, 55, pp. 4-30.
40. Wang, Y., Agerberth, B., Lothgren, A., Almstedt, A. and Johansson, J. (1998) Apolipoprotein A-I binds and inhibits the human antibacterial/ cytotoxic peptide LL-37. J Biol Chem, 273, pp. 33115-33118.
41. Yang, D., Biragyn, A., Hoover, DM, Lubkowski, J. and Oppenheim, JJ (2004) Multiple roles of antimicrobial defensins, cathelicidins, and eosinophil-derived neurotoxin in host defense. Annu Rev Immunol, 22, pp. 181-215.
42. Yount, NY, Bayer, AS, Xiong, YQ and Yeaman, MR (2006) Advances in antimicrobial peptide immunobiology. Biopolymers, 84, pp. 435-458.
43. Zasloff, M. (2002) Antimicrobial peptides of multicellular organisms. Nature, 415, pp. 389-395.
44. Zelezetsky, I. and Tossi, A. (2006) Alpha-helical antimicrobial peptides-Using a sequence template to guide structure-activity relationship studies. Biochim Biophys Acta, 1758, pp. 1436-1449.
45. Zhou, H., Casas-Finet, JR, Coats, R Heath, Kaufman, JD, Stahl, SJ, Wingfield, PT, Rubin, JS, Bottaro, DP and Byrd, RA (1999) Identification and dynamics of a heparin-binding site in hepatocyte growth factor. Biochemistry, 38, pp. 14793-14802.