Mechanisms of G protein activation via the D 2 dopamine receptor: Evidence for persistent receptor/G protein interaction after agonist stimulation

British Journal of Pharmacology

Volumn 151, Issue 1, 2007, Pages 125-133

  Quirk, K ^a   Roberts, D J ^a   Strange, P G ^a  

^a UNIVERSITY OF READING   (United Kingdom)

Author keywords

35S GTP S association; 35S GTP S dissociation; Agonist mechanisms; D 2 dopamine receptor; G proteins; Suramin

Indexed keywords

DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE 2 RECEPTOR STIMULATING AGENT; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); RACLOPRIDE; SULFUR 35; SURAMIN; 10,11 DIHYDROXY N N PROPYLNORAPOMORPHINE; 10,11-DIHYDROXY-N-N-PROPYLNORAPOMORPHINE; APOMORPHINE; DOPAMINE RECEPTOR STIMULATING AGENT; DRUG DERIVATIVE; UNCLASSIFIED DRUG;

AGONIST; ANIMAL CELL; ARTICLE; BINDING ASSAY; BINDING KINETICS; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION; DOPAMINE RECEPTOR BLOCKING; DRUG ANTAGONISM; DRUG EFFICACY; DRUG MECHANISM; DRUG RECEPTOR BINDING; FEMALE; GENETIC TRANSFECTION; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; STIMULATION; ANIMAL; CRICETULUS; DRUG EFFECT; HAMSTER; METABOLISM; PHYSIOLOGY;

ANIMALS; APOMORPHINE; CHO CELLS; CRICETINAE; CRICETULUS; DOPAMINE AGONISTS; GTP-BINDING PROTEINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); RECEPTORS, DOPAMINE D2;

EID: 34247556946     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707197     Document Type: Article

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