Effect of Baccharis dracunculifolia D.C. (Asteraceae) extracts and its isolated compounds on macrophage activation

Journal of Pharmacy and Pharmacology

Volumn 59, Issue 3, 2007, Pages 463-468

  Missima, Fabiane ^a   Da Silva Filho, Ademar A ^b,c   Nunes, Gladston A ^a   Bueno, Paula C Pires ^b   De Sousa, João Paulo B ^b   Bastos, Jairo K ^b   Sforcin, Jose M ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSIDADE DE FRANCA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

11 HYDROXY 10,11 DIHYDROEUPARIN; 6 HYDROXYTREMETONA; AROMADENDRIN 4' METHYL ETHER; BACCHARIN; BACCHARIS DRACUNCULIFOLIA EXTRACT; BACCHARIS OXIDE; COUMARIC ACID; DIHYDROCOUMARIC ACID; DRUPANIN; FRIEDELANOL; HAUTRIWAIC ACID ACETATE; HAUTRIWAIC ACID LACTONE; HYDROGEN PEROXIDE; IMMUNOMODULATING AGENT; ISOSAKURANETIN; PLANT EXTRACT; UNCLASSIFIED DRUG; VISCIDONE; BIOLOGICAL RESPONSE MODIFIER;

ANIMAL EXPERIMENT; ARTICLE; ASTERACEAE; BACCHARIS; CONTROLLED STUDY; DRUG EFFECT; DRUG ISOLATION; DRUG STRUCTURE; IMMUNOMODULATION; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PHYTOCHEMISTRY; PLANT LEAF; PLANT ROOT; ANIMAL; CHEMISTRY; IN VITRO STUDY; ISOLATION AND PURIFICATION; PHYTOTHERAPY; SPECTROSCOPY;

ANIMALS; BACCHARIS; BIOLOGICAL RESPONSE MODIFIERS; MACROPHAGE ACTIVATION; MALE; MICE; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; PLANT ROOTS; SPECTRUM ANALYSIS;

EID: 34247551751     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.59.3.0017     Document Type: Article

References (35)

1. Bankova, V. S., Brasteva, G. B., Sforcin, J. M., Frete, X., Kujumgiev, A., Rodella, R. M., Popov, J. (1999) Phytochemical evidence for the plant origin of Brazilian propolis from São Paulo state. Z. Naturforsch. 54: 401-405
2. Bankova, V. S., Castro, S. L., Marcucci, M. C. (2000) Propolis: recent advances in chemistry and plant origin. Apidologie 31: 3-15
3. Banskota, A. H., Tezuka, Y., Prasain, J. K., Matsushige, K., Saiki, I., Kadota, S. (1998) Chemical constituents of Brazilian propolis and their cytotoxic activities. J. Nat. Prod. 61: 896-900
4. Bazo, A. P., Rodrigues, M. A. M., Sforcin, J. M., Viana de Camargo, J. L., Ribeiro, L. R., Salvadori, D. M. F. (2002) Protective action of propolis on the rat colon carcinogenesis. Teratogen. Carcinogen. Mutagen. 22: 183-194
5. Bohlmann, F., Zdero, C., Grenz, M., Dhar, A. K., Robinson, H., King, R. M. (1981a) Five diterpenes and other constituents from nine Baccharis species. Phytochemistry 20: 1907-1913
6. Bohlmann, F., Ahmed, M., Robinson, H., King, R. M. (1981b) A kolavane derivative from Liatris scariosa. Phytochemistry 6: 1439-1440
7. Bohlmann, F., Zdero, C., Huneck, S. (1985) Diterpenes from Heteropappus altaicus. Phytochemistry 24: 1027-1030
8. Chandler, R. F., Hooper, S. N. (1979) Friedelin and associated triterpenoids. Phytochemistry 18: 711-729
9. Da Silva Filho, A. A., Bueno, P. C. P., Gregorio, L. E., Silva, M. L. A., Albuquerque, S., Bastos, J. K. (2004) In Vitro trypanocidal activity evaluation of crude extract and isolated compounds from Baccharis dracunculifolia D. C. (Asteraceae). J. Pharm. Pharmacol. 56: 1195-1199
10. Grange, J. M., Davey, R. W. (1990) Antibacterial properties of propolis (bee glue). J. Royal Soc. Med. 83: 159-160
11. Kumazawa, S., Yoneda, M., Shibata, I., Kanarda, J., Hamasaka, T., Nakayama, T. (2003) Direct evidence for the plant origin of Brazilian propolis by the observation of honeybee behavior and phytochemical analysis. Chem. Pharm. Bull. 51: 740-742
12. Langner, E., Schilcher, H. (1999) Propolis. Quality and effects of propolis and propolis formulations. Deutcher Apotheker Verlag. 37: 3447-3458
13. Leitão, D. P. S., Da Silva Filho, A. A., Polizello, A. C. M., Bastos, J. K., Spadaro, A. C. C. (2004) Comparative evaluation of in vitro effects of Brazilian green propolis and Baccharis dracunculifolia extracts on cariogenic factors of Streptococcus mutans. Chem. Pharm. Bull. 27: 1834-1839
14. Le-Van, N., Pham, T. V. C. (1981) An unusual m-hydroxyacetophenone and three new derivatives from Chrysothamnus viscidiflorus. Phytochemistry 20: 485-487
15. Loots, D. T., Westhuizen, F. H. V., Jerling, J. (2006) Polyphenol composition and antioxidant activities of Kei-Apple (Dovyalis caffra) juice. J. Agric. Food. Chem. 54: 1271-1276
16. Lopes, F. C., Bankova, V., Sforcin, J. M. (2003) Effect of three vegetal sources of propolis on macrophages activation. Phytomedicine 10: 343
17. Marcucci, M. C. (1995) Propolis: chemical composition, biological properties and therapeutic activity. Apidologie 26: 83-99
18. Mendez, J. (2005) Dihydrocinnamic acids in Pteridium aquilinum. Food Chem. 93: 251-252
19. Moonis, M., Ahmad, I., Bachhawat, B. K. (1992) Macrophages in host defense - an overview. Indian J. Biochem. Biophys. 29: 115-122
20. Murad, J. M., Calvi, S. A., Soares, A. M. V. C., Bankova, V., Sforcin, J. M. (2002) Effects of propolis from Brazil and Bulgaria on fungicidal activity of macrophages against Paracoccidioides brasiliensis. J. Ethnopharmacol. 79: 331-334
21. Nagatami, Y., Warashina, T., Noro, T. (2001) Studies on the constituents from the aerial parts of Baccharis dracunculifolia DC. Chem. Pharm. Bull. 49: 1388-1394
22. Orsi, R. O., Funari, S. R. C., Soares, A. M. V. C., Calvi, S. A., Oliveira, S. L., Sforcin, J. M., Bankova, V. (2000) Immunomodulatory action of propolis on macrophage activation. J. Ven. Anim. Tox. 6: 205-219
23. Orsi, R. O., Sforcin, J. M., Funari, S. R. C., Bankova, V. (2005) Effects of Brazilian and Bulgarian propolis on bactericidal activity of macrophages against Salmonella typhimurium. Int. Immunopharmacol. 5: 359-368
24. Park, Y. K., Alencar, S. M., Aguiar, C. L. (2002) Botanical origin and chemical composition of Brazilian propolis. J. Agric. Food Chem. 50: 2502-2506
25. Park, Y. K., Paredes-Guzman, J. F., Aguiar, C. L., Alencar, S. M., Fujiwara, F. Y. (2004) Chemical constituents in Baccharis dracunculifolia as the main botanical origin of southeastern Brazilian propolis. J. Agric. Food Chem. 52: 1100-1103
26. Pick, E., Mizel, D. (1981) Rapid microassay for the measurement of superoxide and hydrogen peroxide produced by macrophages in culture using an automatic enzyme immunoassay reader. J. Immunol. Methods 46: 2116-2142
27. Queiroga, C. L., Fukai, A., Marsaioli, A. J. (1990) Composition of the essential oil of Vassoura. J. Braz. Chem. Soc. 1: 105-109
28. Reis, C. M. F., Carvalho, J. C. T., Caputo, L. R. G., Patrício, K. C. M., Barbosa, M. V. J., Chieff, A. L., Bastos, J. K. (2000) Atividade antiinflamatória, antiúlcera gástrica e toxicidade subcrôncia do extrato etanólico de própolis. Rev. Bras. Farmacogn. 10: 43-52
29. Saad, J. R., Davicino, J. G., Giordano, O. S. A. (1985) Diterpene and flavonoids of Baccharis flabellata. Phytochemistry. 26: 1884-1887
30. Sforcin, J. M., Fernandes, A. Jr., Lopes, C. A., Bankova, V., Funari, S. R. (2000) Seasonal effect on Brazilian propolis antibacterial activity. J. Ethnopharmacol. 73: 243-252
31. Sforcin, J. M., Kaneno, R., Funari, S. R. C. (2002) Absence of seasonal effect on the immunomodulatory action of Brazilian propolis on natural killer activity. J. Ven. Anim. Tox. 8: 19-29
32. Sforcin, J. M., Orsi, R. O., Bankova, V. (2005) Effect of propolis, some isolated compounds and its source plant on antibody production. J. Ethnopharmacol. 98: 301-305
33. Simões, L. M. C., Gregorio, L. E., Da Silva Filho, A. A., De Souza, M. L., Azzolini, A. E. C. S., Bastos, J. K., Lucisano-Valim, Y. M. (2004) Effect of Brazilian green propolis on the production of reactive oxygen species by stimulated neutrophils. J. Ethnopharmacol. 94: 59-65
34. Zar, J. H. (1996) Bioestatistical analysis. Prentice Hall, New Jersey, pp 718
35. Zhang, X., Morrison, D. C. (1993) Lipopolysaccharide-induced selective priming effects on tumor necrosis factor alpha and nitric oxide production in mouse peritoneal macrophages. J. Exp. Med. 177: 51-516