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Volumn 101, Issue 1, 2007, Pages 244-258

Molecular basis of vanadium-mediated inhibition of hepatocellular preneoplasia during experimental hepatocarcinogenesis in rats

Author keywords

8 OHdGs; Cell proliferation; Chromosomal aberrations; DNA damage; DNA strand breaks; DNA protein crosslinks; Hepatocarcinogenesis; Metallothionein; Preneoplasia; Vanadium

Indexed keywords

8 HYDROXYGUANINE; DEOXYGUANOSINE DERIVATIVE; DIETHYLNITROSAMINE; METALLOTHIONEIN; SINGLE STRANDED DNA; VANADIUM;

EID: 34247521003     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21169     Document Type: Article
Times cited : (14)

References (61)
  • 1
    • 0030076793 scopus 로고    scopus 로고
    • Estimation of single-strand breaks induced in the dried film of DNA by high energy alpha particle from a cyclotron
    • Basak J. 1996. Estimation of single-strand breaks induced in the dried film of DNA by high energy alpha particle from a cyclotron. Ind J Biochem Biophys 33:35-38.
    • (1996) Ind J Biochem Biophys , vol.33 , pp. 35-38
    • Basak, J.1
  • 2
    • 0034551761 scopus 로고    scopus 로고
    • 3 inhibit placental glutathione S-transferase positive foci in rat liver carcinogenesis
    • 3 inhibit placental glutathione S-transferase positive foci in rat liver carcinogenesis. Life Sci 68:217-231.
    • (2000) Life Sci , vol.68 , pp. 217-231
    • Basak, R.1    Chatterjee, M.2
  • 4
    • 0029053449 scopus 로고
    • Time course effects of vanadium supplement on cytosolic reduced glutathione level and glutathione S-transferase activity
    • Bishayee A, Chatterjee M. 1995. Time course effects of vanadium supplement on cytosolic reduced glutathione level and glutathione S-transferase activity. Biol Trace Elem Res 48:275-285.
    • (1995) Biol Trace Elem Res , vol.48 , pp. 275-285
    • Bishayee, A.1    Chatterjee, M.2
  • 5
    • 0032618361 scopus 로고    scopus 로고
    • Characterization of selective induction and alteration of xenobiotic biotransforming enzymes by vanadium during diethylnitrosamine-induced chemical rat liver carcinogenesis
    • Bishayee A, Roy S, Chatterjee M. 1999. Characterization of selective induction and alteration of xenobiotic biotransforming enzymes by vanadium during diethylnitrosamine-induced chemical rat liver carcinogenesis. Oncol Res 11:41-53.
    • (1999) Oncol Res , vol.11 , pp. 41-53
    • Bishayee, A.1    Roy, S.2    Chatterjee, M.3
  • 6
    • 0027732501 scopus 로고
    • Elevated 8-hydroxydeoxyguanosine in hepatic DNA of rats following exposure to peroxisome proliferators: Relationship to carcinogenesis and nuclear localization
    • Cattley RC, Glover SE. 1993. Elevated 8-hydroxydeoxyguanosine in hepatic DNA of rats following exposure to peroxisome proliferators: Relationship to carcinogenesis and nuclear localization. Carcinogenesis 14:2495-2499.
    • (1993) Carcinogenesis , vol.14 , pp. 2495-2499
    • Cattley, R.C.1    Glover, S.E.2
  • 7
    • 21744438611 scopus 로고    scopus 로고
    • Vanadium induces apoptosis and modulates the expressions of metallothionein, Ki-67 nuclear antigen, and p53 during 2-acetylaminofluorene-induced rat liver preneoplasia
    • Chakraborty T, Samanta S, Ghosh B, Thirumoorthy N, Chatterjee M. 2005. Vanadium induces apoptosis and modulates the expressions of metallothionein, Ki-67 nuclear antigen, and p53 during 2-acetylaminofluorene-induced rat liver preneoplasia. J Cell Biochem 94:744-762.
    • (2005) J Cell Biochem , vol.94 , pp. 744-762
    • Chakraborty, T.1    Samanta, S.2    Ghosh, B.3    Thirumoorthy, N.4    Chatterjee, M.5
  • 8
    • 0027497437 scopus 로고
    • N-nitrosodimethylamine, N-nitrosodiethylamine, and N-nitrosomorpholine fail to generate 8-hydroxy-2′-deoxyguanosine in liver DNA of male F344 rats
    • Dahlaus M, Appel KE. 1993. N-nitrosodimethylamine, N-nitrosodiethylamine, and N-nitrosomorpholine fail to generate 8-hydroxy-2′-deoxyguanosine in liver DNA of male F344 rats. Mutat Res 285:295-302.
    • (1993) Mutat Res , vol.285 , pp. 295-302
    • Dahlaus, M.1    Appel, K.E.2
  • 9
    • 0036911350 scopus 로고    scopus 로고
    • Metvan: A novel oxovanadium(IV) complex with broad spectrum anticancer activity
    • D'Cruz OJ, Uckun FM. 2002. Metvan: A novel oxovanadium(IV) complex with broad spectrum anticancer activity. Expert Opin Invest Drugs 11:1829-1836.
    • (2002) Expert Opin Invest Drugs , vol.11 , pp. 1829-1836
    • D'Cruz, O.J.1    Uckun, F.M.2
  • 10
    • 27844439469 scopus 로고    scopus 로고
    • Overview of mechanisms of cancer chemopreventive agents
    • De Flora S, Ferguson LR. 2005. Overview of mechanisms of cancer chemopreventive agents. Mutat Res 591:8-15.
    • (2005) Mutat Res , vol.591 , pp. 8-15
    • De Flora, S.1    Ferguson, L.R.2
  • 11
    • 22344452155 scopus 로고    scopus 로고
    • Geranylgeraniol and beta-ionone inhibit hepatic preneoplastic lesions, cell proliferation, total plasma cholesterol and DNA damage during the initial phases of hepatocarcinogenesis, but only the former inhibits NF-kappaB activation
    • de Moura Espindola R, Mazzantini RP, Ong TP, de Conti A, Heidor R, Moreno FS. 2005. Geranylgeraniol and beta-ionone inhibit hepatic preneoplastic lesions, cell proliferation, total plasma cholesterol and DNA damage during the initial phases of hepatocarcinogenesis, but only the former inhibits NF-kappaB activation. Carcinogenesis 26:1091-1099.
    • (2005) Carcinogenesis , vol.26 , pp. 1091-1099
    • de Moura Espindola, R.1    Mazzantini, R.P.2    Ong, T.P.3    de Conti, A.4    Heidor, R.5    Moreno, F.S.6
  • 12
    • 0027989716 scopus 로고
    • Incorporation of bromodeoxyuridine in glutathione S-transferase-positive hepatocytes during rat multistage hepatocarcinogenesis
    • Dragon YP, Hully J, Crow R, Mass M, Pitot HC. 1994. Incorporation of bromodeoxyuridine in glutathione S-transferase-positive hepatocytes during rat multistage hepatocarcinogenesis. Carcinogenesis 15:1939-1947.
    • (1994) Carcinogenesis , vol.15 , pp. 1939-1947
    • Dragon, Y.P.1    Hully, J.2    Crow, R.3    Mass, M.4    Pitot, H.C.5
  • 13
    • 0036273321 scopus 로고    scopus 로고
    • Vanadium in cancer treatment
    • Evangelou AM. 2002. Vanadium in cancer treatment. Crt Rev Oncol Hematol 42:249-265.
    • (2002) Crt Rev Oncol Hematol , vol.42 , pp. 249-265
    • Evangelou, A.M.1
  • 14
    • 0021750659 scopus 로고
    • Cellular biochemistry of the stepwise development of cancer with chemicals
    • Farber E. 1984a. Cellular biochemistry of the stepwise development of cancer with chemicals. Cancer Res 44:5463-5474.
    • (1984) Cancer Res , vol.44 , pp. 5463-5474
    • Farber, E.1
  • 15
    • 0021601376 scopus 로고
    • The multistep nature of cancer development
    • Farber E. 1984b. The multistep nature of cancer development. Cancer Res 44:4217-4223.
    • (1984) Cancer Res , vol.44 , pp. 4217-4223
    • Farber, E.1
  • 16
    • 0025370064 scopus 로고
    • Clonal adaptation during carcinogenesis
    • Farber E. 1990. Clonal adaptation during carcinogenesis. Biochem Pharmacol 39:1837-1846.
    • (1990) Biochem Pharmacol , vol.39 , pp. 1837-1846
    • Farber, E.1
  • 17
    • 0018873482 scopus 로고
    • The sequential analysis of cancer development
    • Farber E, Cameron R. 1980. The sequential analysis of cancer development. Adv Cancer Res 31:125-226.
    • (1980) Adv Cancer Res , vol.31 , pp. 125-226
    • Farber, E.1    Cameron, R.2
  • 18
    • 0025045198 scopus 로고
    • The role of 8-hydroxyguanine in carcinogenesis
    • Floyd RA. 1990. The role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis 11:1447-1450.
    • (1990) Carcinogenesis , vol.11 , pp. 1447-1450
    • Floyd, R.A.1
  • 19
    • 0027510042 scopus 로고
    • Role of vanadium in nutrition: Metabolism, essentiality and dietary consideration
    • French RJ, Jones PJ. 1993. Role of vanadium in nutrition: Metabolism, essentiality and dietary consideration. Life Sci 52:339-346.
    • (1993) Life Sci , vol.52 , pp. 339-346
    • French, R.J.1    Jones, P.J.2
  • 20
    • 0015011604 scopus 로고
    • Cytogenetic studies in Sprague-Dawley rats during the administration of carcinogen nitroso compound-diethynitrosamine
    • Grover S, Fisher P. 1971. Cytogenetic studies in Sprague-Dawley rats during the administration of carcinogen nitroso compound-diethynitrosamine. Eur J Cancer 7:77-82.
    • (1971) Eur J Cancer , vol.7 , pp. 77-82
    • Grover, S.1    Fisher, P.2
  • 21
    • 0000530035 scopus 로고
    • Nonrandom binding of the carcinogen N-hydroxy-2- acetylaminofluorene to repetitive sequences of rat liver DNA in vivo
    • Gupta RC. 1984. Nonrandom binding of the carcinogen N-hydroxy-2- acetylaminofluorene to repetitive sequences of rat liver DNA in vivo. Proc Natl Acad Sci USA 81:6943-6947.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 6943-6947
    • Gupta, R.C.1
  • 22
    • 4544239326 scopus 로고    scopus 로고
    • Inorganic oxo compounds react with alkylating agents: Implications for DNA damage
    • Hamilton EE, Wilker JJ. 2004a. Inorganic oxo compounds react with alkylating agents: Implications for DNA damage. Angew Chem Int Ed Eng 43:3290-3292.
    • (2004) Angew Chem Int Ed Eng , vol.43 , pp. 3290-3292
    • Hamilton, E.E.1    Wilker, J.J.2
  • 23
    • 8644271520 scopus 로고    scopus 로고
    • Inhibition of DNA alkylation damage with inorganic salts
    • Hamilton EE, Wilker JJ. 2004b. Inhibition of DNA alkylation damage with inorganic salts. J Biol Inorg Chem 9:894-902.
    • (2004) J Biol Inorg Chem , vol.9 , pp. 894-902
    • Hamilton, E.E.1    Wilker, J.J.2
  • 24
    • 0037045251 scopus 로고    scopus 로고
    • The elusive vanadate (V(3)O(9))(3-): Isolation, crystal structure, and nonaqueous solution behavior
    • Hamilton EE, Fanwick PE, Wilker JJ. 2002. The elusive vanadate (V(3)O(9))(3-): Isolation, crystal structure, and nonaqueous solution behavior. J Am Chem Soc 124:78-82.
    • (2002) J Am Chem Soc , vol.124 , pp. 78-82
    • Hamilton, E.E.1    Fanwick, P.E.2    Wilker, J.J.3
  • 25
    • 33644944459 scopus 로고    scopus 로고
    • Alkylation of inorganic oxo compounds and insights on preventing DNA damage
    • Hamilton EE, Fanwick PE, Wilker JJ. 2006. Alkylation of inorganic oxo compounds and insights on preventing DNA damage. J Am Chem Soc 128:3388-3395.
    • (2006) J Am Chem Soc , vol.128 , pp. 3388-3395
    • Hamilton, E.E.1    Fanwick, P.E.2    Wilker, J.J.3
  • 26
    • 0001940329 scopus 로고
    • The biological essentiality of vanadium
    • Mertz W, Cornatzer WE, editors, New York: Marcel Dekker. pp
    • Hopkins LL, Jr., Mohr HE. 1971. The biological essentiality of vanadium. In: Mertz W, Cornatzer WE, editors. Newer trace elements in nutrition. New York: Marcel Dekker. pp 195-213.
    • (1971) Newer trace elements in nutrition , pp. 195-213
    • Hopkins Jr., L.L.1    Mohr, H.E.2
  • 27
    • 0021164404 scopus 로고
    • Sensitive induction of chromosome aberration in the in-vivo liver cells of rats by N- nitrosodiethylamine
    • Horiuchi T, Ito K, Suzuki M, Umeda M. 1984. Sensitive induction of chromosome aberration in the in-vivo liver cells of rats by N- nitrosodiethylamine. Mutat Res 140:181-185.
    • (1984) Mutat Res , vol.140 , pp. 181-185
    • Horiuchi, T.1    Ito, K.2    Suzuki, M.3    Umeda, M.4
  • 28
    • 0036679202 scopus 로고    scopus 로고
    • Metallothionein expression in hepatocellular carcinoma
    • Huang GW, Yang LY. 2002. Metallothionein expression in hepatocellular carcinoma. World J Gastroenterol 8:650-653.
    • (2002) World J Gastroenterol , vol.8 , pp. 650-653
    • Huang, G.W.1    Yang, L.Y.2
  • 29
    • 0036261707 scopus 로고    scopus 로고
    • Sensing and repairing DNA double-strand breaks
    • Jackson SP. 2002. Sensing and repairing DNA double-strand breaks. Carcinogenesis 23:687-696.
    • (2002) Carcinogenesis , vol.23 , pp. 687-696
    • Jackson, S.P.1
  • 30
    • 0033782829 scopus 로고    scopus 로고
    • Proliferative potential in nasopharyngeal carcinoma: Correlations with metallothionein expression and tissue zinc levels
    • Jayasurya A, Bay BH, Yap WM, Tan NG, Tan BKH. 2000. Proliferative potential in nasopharyngeal carcinoma: Correlations with metallothionein expression and tissue zinc levels. Carcinogenesis 21:1809-1812.
    • (2000) Carcinogenesis , vol.21 , pp. 1809-1812
    • Jayasurya, A.1    Bay, B.H.2    Yap, W.M.3    Tan, N.G.4    Tan, B.K.H.5
  • 31
    • 0036783225 scopus 로고    scopus 로고
    • DNA damage triggers imbalance of proliferation and apoptosis during development of preneoplastic foci in the liver of Long-Evans Cinnamon rats
    • Jia G, Tohyama C, Sone H. 2002. DNA damage triggers imbalance of proliferation and apoptosis during development of preneoplastic foci in the liver of Long-Evans Cinnamon rats. Int J Oncol 21:755-761.
    • (2002) Int J Oncol , vol.21 , pp. 755-761
    • Jia, G.1    Tohyama, C.2    Sone, H.3
  • 33
    • 0031469841 scopus 로고    scopus 로고
    • Analysis of a form of oxidative DNA damage, 8-hydroxyguanosine, as a marker of cellular oxidative stress during carcinogenesis
    • Kasai H. 1997. Analysis of a form of oxidative DNA damage, 8-hydroxyguanosine, as a marker of cellular oxidative stress during carcinogenesis. Mutat Res 387:147-163.
    • (1997) Mutat Res , vol.387 , pp. 147-163
    • Kasai, H.1
  • 34
    • 0022825053 scopus 로고
    • The role of calcium, magnesium, and zinc in carcinogenesis
    • Kasprzak KS, Waalkes MP. 1986. The role of calcium, magnesium, and zinc in carcinogenesis. Adv Exp Med Biol 206:497-515.
    • (1986) Adv Exp Med Biol , vol.206 , pp. 497-515
    • Kasprzak, K.S.1    Waalkes, M.P.2
  • 35
    • 13344275858 scopus 로고    scopus 로고
    • Dose-dependent induction of 8-hydroxyguanine and preneoplastic foci in rat liver by food-derived carcinogen, 2-amino-3,8- dimethylimidazo[4,5-f]quinoline at low dose levels
    • Kato T, Hasegawa R, Nakae D, Hirose M, Yamao M, Kobayashi Y, Konishi Y, Ito N, Shirai T. 1996. Dose-dependent induction of 8-hydroxyguanine and preneoplastic foci in rat liver by food-derived carcinogen, 2-amino-3,8- dimethylimidazo[4,5-f]quinoline at low dose levels. Jpn J Cancer Res 87:127-133.
    • (1996) Jpn J Cancer Res , vol.87 , pp. 127-133
    • Kato, T.1    Hasegawa, R.2    Nakae, D.3    Hirose, M.4    Yamao, M.5    Kobayashi, Y.6    Konishi, Y.7    Ito, N.8    Shirai, T.9
  • 36
    • 0000887595 scopus 로고
    • Transition and main-group metal cyclopentadienyl complexes: Preclinical studies on a series of antitumor agents of different structural type
    • Kopf-Maier P, Kopf H. 1988. Transition and main-group metal cyclopentadienyl complexes: Preclinical studies on a series of antitumor agents of different structural type. Struct Bond 70:103-185.
    • (1988) Struct Bond , vol.70 , pp. 103-185
    • Kopf-Maier, P.1    Kopf, H.2
  • 37
    • 0028069885 scopus 로고
    • Complexes of metals other than platinum as anti-tumour agents
    • Köpf-Maier P. 1994. Complexes of metals other than platinum as anti-tumour agents. Eur J Clin Pharmacol 47:1-16.
    • (1994) Eur J Clin Pharmacol , vol.47 , pp. 1-16
    • Köpf-Maier, P.1
  • 38
    • 0021063848 scopus 로고
    • Cellular oncogenes and multistep carcinogenesis
    • Land H, Parada LF, Weinberg RA. 1983. Cellular oncogenes and multistep carcinogenesis. Science 222:771-778.
    • (1983) Science , vol.222 , pp. 771-778
    • Land, H.1    Parada, L.F.2    Weinberg, R.A.3
  • 39
    • 0024348029 scopus 로고
    • 3H-thymidine for studies of hepatocellular proliferation in rodents
    • 3H-thymidine for studies of hepatocellular proliferation in rodents. Carcinogenesis 10:1341-1343.
    • (1989) Carcinogenesis , vol.10 , pp. 1341-1343
    • Lanier, T.1    Berger, E.2    Eacho, P.3
  • 40
    • 0027278557 scopus 로고
    • Instability and decay of the primary structure of DNA
    • Lindahl T. 1993. Instability and decay of the primary structure of DNA. Nature 362:709-715.
    • (1993) Nature , vol.362 , pp. 709-715
    • Lindahl, T.1
  • 41
    • 0025941669 scopus 로고
    • Inhibitory effect of β-carotene on preneoplastic lesions induced in Wistar rats by the resistant hepatocyte model
    • Moreno FS, Rizzi MBSL, Dagli MLZ, Penteado MVC. 1991. Inhibitory effect of β-carotene on preneoplastic lesions induced in Wistar rats by the resistant hepatocyte model. Carcinogenesis 12:1817-1822.
    • (1991) Carcinogenesis , vol.12 , pp. 1817-1822
    • Moreno, F.S.1    Rizzi, M.B.S.L.2    Dagli, M.L.Z.3    Penteado, M.V.C.4
  • 42
    • 0030940501 scopus 로고    scopus 로고
    • Involvement of 8-hydroxyguanine formation in the initiation of rat liver carcinogenesis by low dose levels of N-nitrosodiethylamine
    • Nakae D, Kobayashi Y, Akai H, Andoh N, Satox H, Ohashi K, Tsutsumi M, Konishi Y. 1997. Involvement of 8-hydroxyguanine formation in the initiation of rat liver carcinogenesis by low dose levels of N-nitrosodiethylamine. Cancer Res 57:1281-1287.
    • (1997) Cancer Res , vol.57 , pp. 1281-1287
    • Nakae, D.1    Kobayashi, Y.2    Akai, H.3    Andoh, N.4    Satox, H.5    Ohashi, K.6    Tsutsumi, M.7    Konishi, Y.8
  • 43
    • 0035020025 scopus 로고    scopus 로고
    • Vanadocenes as potent anti-proliferative agents disrupting mitotic spindle formation in cancer cells
    • Navara CS, Benyumov A, Vassilev A, Narla RK, Ghosh P, Uckun FM. 2001. Vanadocenes as potent anti-proliferative agents disrupting mitotic spindle formation in cancer cells. Anticancer Res 12:369-376.
    • (2001) Anticancer Res , vol.12 , pp. 369-376
    • Navara, C.S.1    Benyumov, A.2    Vassilev, A.3    Narla, R.K.4    Ghosh, P.5    Uckun, F.M.6
  • 44
    • 0001774653 scopus 로고
    • The essentiality and metabolism of vanadium
    • Chasteen ND, editor, Dordrecht: Kluwer Academic Publishers. pp
    • Nielsen FH, Uthus EO. 1980. The essentiality and metabolism of vanadium. In: Chasteen ND, editor. Vanadium in biological systems. Dordrecht: Kluwer Academic Publishers. pp 51-62.
    • (1980) Vanadium in biological systems , pp. 51-62
    • Nielsen, F.H.1    Uthus, E.O.2
  • 45
    • 0023224875 scopus 로고
    • The formation, identification, and significance of DNA-protein crosslinks in mammalian cells
    • Oleinick NL, Chiu SM, Ramakrishnan N, Xue LY. 1987. The formation, identification, and significance of DNA-protein crosslinks in mammalian cells. Br J Cancer 55:135-140.
    • (1987) Br J Cancer , vol.55 , pp. 135-140
    • Oleinick, N.L.1    Chiu, S.M.2    Ramakrishnan, N.3    Xue, L.Y.4
  • 46
    • 0029963964 scopus 로고    scopus 로고
    • Immunohistochemical expression of metallothionein in invasive breast cancer in relation to proliferative activity, histology and prognosis
    • Oyama T, Take H, Hikino T, Lino Y, Nakajima T. 1996. Immunohistochemical expression of metallothionein in invasive breast cancer in relation to proliferative activity, histology and prognosis. Oncology 53:112-117.
    • (1996) Oncology , vol.53 , pp. 112-117
    • Oyama, T.1    Take, H.2    Hikino, T.3    Lino, Y.4    Nakajima, T.5
  • 47
    • 0024523950 scopus 로고
    • Detection of DNA adducts by high-performance liquid chromatography with electrochemical detection
    • Park JW, Cundi KC, Ames BN. 1989. Detection of DNA adducts by high-performance liquid chromatography with electrochemical detection. Carcinogenesis 10:827-832.
    • (1989) Carcinogenesis , vol.10 , pp. 827-832
    • Park, J.W.1    Cundi, K.C.2    Ames, B.N.3
  • 48
    • 0019857947 scopus 로고
    • Early appearance of histochemically altered hepatocyte foci and liver tumors in female rats treated with carcinogens one day after birth
    • Peraino C, Staffeldt EF, Ludeman VA. 1981. Early appearance of histochemically altered hepatocyte foci and liver tumors in female rats treated with carcinogens one day after birth. Carcinogenesis 2:463-465.
    • (1981) Carcinogenesis , vol.2 , pp. 463-465
    • Peraino, C.1    Staffeldt, E.F.2    Ludeman, V.A.3
  • 49
    • 0028796632 scopus 로고
    • Mechanism for a new antitumor vanadium complex: Hydroxyl radical dependent DNA cleavage by 1, 10-phenanthroline-vanadyl complex in the presence of hydrogen peroxide
    • Sakurai H, Tamura H, Okatani K. 1995. Mechanism for a new antitumor vanadium complex: Hydroxyl radical dependent DNA cleavage by 1, 10-phenanthroline-vanadyl complex in the presence of hydrogen peroxide. Biochem Biophys Res Commun 206:133-137.
    • (1995) Biochem Biophys Res Commun , vol.206 , pp. 133-137
    • Sakurai, H.1    Tamura, H.2    Okatani, K.3
  • 50
    • 0030769237 scopus 로고    scopus 로고
    • Beta carotene prevents rat liver chromosomal aberrations and DNA chain break after a single injection of diethylnitrosamine
    • Sarkar A, Basak R, Basak J, Chatterjee M. 1997. Beta carotene prevents rat liver chromosomal aberrations and DNA chain break after a single injection of diethylnitrosamine. Br J Cancer 76:855-861.
    • (1997) Br J Cancer , vol.76 , pp. 855-861
    • Sarkar, A.1    Basak, R.2    Basak, J.3    Chatterjee, M.4
  • 51
    • 0019475270 scopus 로고
    • Enhanced proliferation of putative preneoplastic cells in rat liver following treatment with the tumor promoters phenobarbital, hexachlorocyclohexane, steroid compounds, and nafenopin
    • Schulte-Hermann R, Ohde G, Schuppler J, Timmermann-Trosiener I. 1981. Enhanced proliferation of putative preneoplastic cells in rat liver following treatment with the tumor promoters phenobarbital, hexachlorocyclohexane, steroid compounds, and nafenopin. Cancer Res 41:2556-2562.
    • (1981) Cancer Res , vol.41 , pp. 2556-2562
    • Schulte-Hermann, R.1    Ohde, G.2    Schuppler, J.3    Timmermann-Trosiener, I.4
  • 54
    • 0035922197 scopus 로고    scopus 로고
    • Resveratrol, a natural phenolic compound, inhibits cell proliferation and prevents oxidative DNA damage
    • Sgambato A, Ardito R, Faraglia B, Boninsegna A, Wolf FI, Cittadini A. 2001. Resveratrol, a natural phenolic compound, inhibits cell proliferation and prevents oxidative DNA damage. Mutat Res 496:171-180.
    • (2001) Mutat Res , vol.496 , pp. 171-180
    • Sgambato, A.1    Ardito, R.2    Faraglia, B.3    Boninsegna, A.4    Wolf, F.I.5    Cittadini, A.6
  • 55
    • 0028984962 scopus 로고
    • Aflatoxin B1-induced 8-hydroxydeoxyguanosine formation in rat hepatic DNA
    • Shen HM, Ong CN, Lee BL, Shi CY. 1995. Aflatoxin B1-induced 8-hydroxydeoxyguanosine formation in rat hepatic DNA. Carcinogenesis 16:419-422.
    • (1995) Carcinogenesis , vol.16 , pp. 419-422
    • Shen, H.M.1    Ong, C.N.2    Lee, B.L.3    Shi, C.Y.4
  • 56
    • 0242643756 scopus 로고    scopus 로고
    • Liver tumorigenicity of trimethylarsine oxide in male Fischer 344 rats - association with oxidative DNA damage and enhanced cell proliferation
    • Shen J, Wanibuchi H, Salim EI, Wei M, Kinoshita A, Yoshida K, Endo G, Fukushima S. 2003. Liver tumorigenicity of trimethylarsine oxide in male Fischer 344 rats - association with oxidative DNA damage and enhanced cell proliferation. Carcinogenesis 24:1827-1835.
    • (2003) Carcinogenesis , vol.24 , pp. 1827-1835
    • Shen, J.1    Wanibuchi, H.2    Salim, E.I.3    Wei, M.4    Kinoshita, A.5    Yoshida, K.6    Endo, G.7    Fukushima, S.8
  • 57
    • 0027572351 scopus 로고
    • Vanadium as a modulator of cellular regulatory cascades and oncogene expression
    • Stern A, Yin X, Tsang SS, Davidson A, Moon AJ. 1993. Vanadium as a modulator of cellular regulatory cascades and oncogene expression. Biochem Cell Biol 71:103-112.
    • (1993) Biochem Cell Biol , vol.71 , pp. 103-112
    • Stern, A.1    Yin, X.2    Tsang, S.S.3    Davidson, A.4    Moon, A.J.5
  • 59
    • 0022539348 scopus 로고
    • Comparison of DNA lesions and cytotoxicity induced by calcium chromate in human, mouse, and hamster cell lines
    • Sugiyama M, Wang XW, Costa M. 1986. Comparison of DNA lesions and cytotoxicity induced by calcium chromate in human, mouse, and hamster cell lines. Cancer Res 46:4547-4551.
    • (1986) Cancer Res , vol.46 , pp. 4547-4551
    • Sugiyama, M.1    Wang, X.W.2    Costa, M.3
  • 60
    • 0022390503 scopus 로고
    • Association between DNA strand breaks and specific DNA adducts in murine hepatocytes following in vivo and in vitro exposure to N-hydroxy-2- acetylaminofluorene and N-acetoxy-2-acetylaminofluorene
    • Vu V, Moller ME, Grantham PH, Wirth PJ, Thorgeirsson SS. 1985. Association between DNA strand breaks and specific DNA adducts in murine hepatocytes following in vivo and in vitro exposure to N-hydroxy-2- acetylaminofluorene and N-acetoxy-2-acetylaminofluorene. Carcinogenesis 6:45-52.
    • (1985) Carcinogenesis , vol.6 , pp. 45-52
    • Vu, V.1    Moller, M.E.2    Grantham, P.H.3    Wirth, P.J.4    Thorgeirsson, S.S.5
  • 61
    • 0026802253 scopus 로고
    • A simple, sensitive assay to detect DNA-protein crosslinks in intact cells and in vivo
    • Zhitkovich A, Costa MA. 1992. A simple, sensitive assay to detect DNA-protein crosslinks in intact cells and in vivo. Carcinogenesis 13:1485-1489.
    • (1992) Carcinogenesis , vol.13 , pp. 1485-1489
    • Zhitkovich, A.1    Costa, M.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.