Interleukin-12- and interferon-γ-mediated natural killer cell activation by Agaricus blazei Murill

Immunology

Volumn 121, Issue 2, 2007, Pages 197-206

  Yuminamochi, Eri ^a,b   Koike, Taisuke ^a,b   Takeda, Kazuyoshi ^a   Horiuchi, Isao ^b   Okumura, Ko ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Japan Appl Microbiol Res Inst L   (Japan)

Author keywords

Agaricus blazei; Cytotoxicity; IFN ; IL 12; NK cells

Indexed keywords

AGARICUS BLAZEI EXTRACT; CELLULASE; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 12 ANTIBODY; INTERLEUKIN 18 ANTIBODY; RAG2 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; BAGG ALBINO MOUSE; C3H MOUSE; C57BL 6 MOUSE; CELL ACTIVATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DENDRITIC CELL; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOSTIMULATION; IN VITRO STUDY; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; SPLEEN CELL; WILD TYPE;

AGARICUS; ANIMALS; CELLS, CULTURED; CYTOTOXICITY, IMMUNOLOGIC; DENDRITIC CELLS; INTERFERON TYPE II; INTERLEUKIN-12; KILLER CELLS, NATURAL; MALE; MICE; MICE, INBRED STRAINS; SPLEEN;

EID: 34247512885     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2006.02558.x     Document Type: Article

References (44)

1. Takaku T, Kimura Y, Okuda H. Isolation of an antitumor compound from Agaricus blazei Murill and its mechanism of action. J Nutr 2001 131 : 1409 13.
2. Yoshimura K, Ueda N, Ichioka K, Matsui Y, Terai A, Arai Y. Use of complementary and alternative medicine by patients with urologic cancer: a prospective study at a single Japanese institution. Support Care Cancer 2005 13 : 685 90.
3. Takeda K, Okumura K. CAM and NK cells. Evid Based Complement Alternat Med 2004 1 : 17 27.
4. Ahn WS, Kim DJ, Chae GT et al. Natural killer cell activity and quality of life were improved by consumption of a mushroom extract, Agaricus blazei Murill Kyowa, in gynecological cancer patients undergoing chemotherapy. Int J Gynecol Cancer 2004 14 : 589 94.
5. Itoh H, Ito H, Amano H, Noda H. Inhibitory action of a (1→6)-β-d-glucan-protein complex (FIII-2-b) isolated from Agaricus blazei Murill ('himematsutake') on Meth A fibrosarcoma-bearing mice and its antitumor mechanism. Jpn J Pharmacol 1994 66 : 265 71.
6. Ohno N, Furukawa M, Miura NN, Adachi Y, Motoi M, Yadomae T. Antitumor β glucan from the cultured fruit body of Agaricus blazei. Biol Pharm Bull 2001 24 : 820 8.
7. Oshiman K, Fujimiya Y, Ebina T, Suzuki I, Noji M. Orally administered β-1,6-d-polyglucose extracted from Agaricus blazei results in tumor regression in tumor-bearing mice. Planta Med 2002 68 : 610 4.
8. Kobayashi H, Yoshida R, Kanada Y et al. Suppressing effects of daily oral supplementation of β-glucan extracted from Agaricus blazei Murill on spontaneous and peritoneal disseminated metastasis in mouse model. J Cancer Res Clin Oncol 2005 131 : 527 38.
9. Lee YL, Kim HJ, Lee MS, Kim JM, Han JS, Hong EK, Kwon MS, Lee MJ. Oral administration of Agaricus blazei (H1 strain) inhibited tumor growth in a sarcoma 180 inoculation model. Exp Anim 2003 52 : 371 5.
10. Takimoto H, Wakita D, Kawaguchi K, Kumazawa Y. Potentiation of cytotoxic activity in naive and tumor-bearing mice by oral administration of hot-water extracts from Agaricus brazei fruiting bodies. Biol Pharm Bull 2004 27 : 404 6.
11. Kimura Y, Kido T, Takaku T, Sumiyoshi M, Baba K. Isolation of an anti-angiogenic substance from Agaricus blazei Murill: its antitumor and antimetastatic actions. Cancer Sci 2004 95 : 758 64.
12. Yokoyama WM, Scalzo AA. Natural killer cell activation receptors in innate immunity to infection. Microbes Infect 2002 4 : 1513 21.
13. Biron CA, Brossay L. NK cells and NKT cells in innate defense against viral infections. Curr Opin Immunol 2001 13 : 458 64.
14. Talmadge JE, Meyers KM, Prieur DJ, Starkey JR. Role of NK cells in tumour growth and metastasis in beige mice. Nature 1980 284 : 622 4.
15. Smyth MJ, Hayakawa Y, Takeda K, Yagita H. New aspects of natural-killer-cell surveillance and therapy of cancer. Nat Rev Cancer 2002 2 : 850 61.
16. Fujimiya Y, Suzuki Y, Oshiman K et al. Selective tumoricidal effect of soluble proteoglucan extracted from the basidiomycete, Agaricus blazei Murill, mediated via natural killer cell activation and apoptosis. Cancer Immunol Immunother 1998 46 : 147 59.
17. Zhong M, Tai A, Yamamoto I. In vitro augmentation of natural killer activity and interferon-γ production in murine spleen cells with Agaricus blazei fruiting body fractions. Biosci Biotechnol Biochem 2005 69 : 2466 9.
18. Kaneno R, Fontanari LM, Santos SA, Di Stasi LC, Rodrigues Filho E, Eira AF. Effects of extracts from Brazilian sun-mushroom (Agaricus blazei) on the NK activity and lymphoproliferative responsiveness of Ehrlich tumor-bearing mice. Food Chem Toxicol 2004 42 : 909 16.
19. Takeda K, Hayakawa Y, Smyth MJ et al. Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells. Nat Med 2001 7 : 94 100.
20. Kasai H, He LM, Kawamura M et al. IL-12 production induced by Agaricus blazei fraction H (ABH) involves Toll-like receptor (TLR). Evid Based Complement Alternat Med 2004 1 : 259 67.
21. Hashimoto W, Takeda K, Anzai R, Ogasawara K, Sakihara H, Sugiura K, Seki S, Kumagai K. Cytotoxic NK1.1 Ag+αβ T cells with intermediate TCR induced in the liver of mice by IL-12. J Immunol 1995 154 : 4333 40.
22. Yamazaki T, Akiba H, Iwai H et al. Expression of programmed death 1 ligands by murine T cells and APC. J Immunol 2002 169 : 5538 45.
23. Maldonado-Lopez R, De Smedt T, Michel P et al. CD8α+ and CD8α- subclasses of dendritic cells direct the development of distinct T helper cells in vivo. J Exp Med 1999 189 : 587 92.
24. Poltorak A, He X, Smirnova I et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998 282 : 2085 8.
25. Jacobs MD, Morrison DC. Dissociation between mitogenicity and immunogenicity of TNP-lipopolysaccharide, a T-independent antigen. J Exp Med 1975 141 : 1453 8.
26. Dunn GP, Bruce AT, Ikeda H, Old LJ, Schreiber RD. Cancer immunoediting: from immunosurveillance to tumor escape. Nat Immunol 2002 3 : 991 8.
27. Smyth MJ, Dunn GP, Schreiber RD. Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity. Adv Immunol 2006 90 : 1 50.
28. Brunda MJ. Interleukin-12. J Leukoc Biol 1994 55 : 280 8.
29. Trinchieri G. Interleukin-12. A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu Rev Immunol 1995 13 : 251 76.
30. Okamura H, Kashiwamura S, Tsutsui H, Yoshimoto T, Nakanishi K. Regulation of interferon-γ production by IL-12 and IL-18. Curr Opin Immunol 1998 10 : 259 64.
31. van den Broek ME, Kagi D, Ossendorp F et al. Decreased tumor surveillance in perforin-deficient mice. J Exp Med 1996 184 : 1781 90.
32. Smyth MJ, Thia KY, Cretney E, Kelly JM, Snook MB, Forbes CA, Scalzo AA. Perforin is a major contributor to NK cell control of tumor metastasis. J Immunol 1999 162 : 6658 62.
33. Nastala CL, Edington HD, McKinney TG et al. Recombinant IL-12 administration induces tumor regression in association with IFN-γ production. J Immunol 1994 153 : 1697 706.
34. YuWG, Yamamoto N, Takenaka H et al. Molecular mechanisms underlying IFN-γ-mediated tumor growth inhibition induced during tumor immunotherapy with rIL-12. Int Immunol 1996 8 : 855 65.
35. Tannenbaum CS, Tubbs R, Armstrong D, Finke JH, Bukowski RM, Hamilton TA. The CXC chemokines IP-10 and Mig are necessary for IL-12-mediated regression of the mouse RENCA tumor. J Immunol 1998 161 : 927 32.
36. Ellertsen LK, Hetland G, Johnson E, Grinde B. Effect of a medicinal extract from Agaricus blazei Murill on gene expression in a human monocyte cell line as examined by microarrays and immuno assays. Int Immunopharmacol 2006 6 : 133 43.
37. Kawagishi H, Inagaki R, Kanao T, Mizuno T, Shimura K, Ito H, Hagiwara T, Nakamura T. Fractionation and antitumor activity of the water-insoluble residue of Agaricus blazei fruiting bodies. Carbohydr Res 1989 186 : 267 73.
38. Brown GD, Gordon S. Immune recognition. A new receptor for β-glucans. Nature 2001 413 : 36 7.
39. Brown GD. Dectin-1: a signalling non-TLR pattern-recognition receptor. Nat Rev Immunol 2006 6 : 33 43.
40. Underhill DM, Ozinsky A, Hajjar AM, Stevens A, Wilson CB, Bassetti M, Aderem A. The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature 1999 401 : 811 5.
41. Ozinsky A, Underhill DM, Fontenot JD, Hajjar AM, Smith KD, Wilson CB, Schroeder L, Aderem A. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc Natl Acad Sci U S A 2000 97 : 13766 71.
42. Kodama T, Takeda K, Shimozato O et al. Perforin-dependent NK cell cytotoxicity is sufficient for anti-metastatic effect of IL-12. Eur J Immunol 1999 29 : 1390 6.
43. Ozmen L, Pericin M, Hakimi J, Chizzonite RA, Wysocka M, Trinchieri G, Gately M, Garotta G. Interleukin 12, interferon γ, and tumor necrosis factor α are the key cytokines of the generalized Shwartzman reaction. J Exp Med 1994 180 : 907 15.
44. Tsutsui H, Matsui K, Kawada N, Hyodo Y, Hayashi N, Okamura H, Higashino K, Nakanishi K. IL-18 accounts for both TNF-α- and Fas ligand-mediated hepatotoxic pathways in endotoxin-induced liver injury in mice. J Immunol 1997 159 : 3961 7.