The integrated action of oestrogen receptor isoforms and sites with progesterone receptor in the gonadotrope modulates LH secretion: Evidence from tamoxifen-treated ovariectomized rats

Journal of Endocrinology

Volumn 193, Issue 1, 2007, Pages 107-119

  Garrido Gracia, José C ^a   Gordon, Ana ^a   Bellido, Carmina ^a   Aguilar, Rafaela ^a   Barranco, Inmaculada ^a   Millán, Yolanda ^a   de las Mulas, Juana Martín ^a   Sánchez Criado, José E ^a,b  

^a UNIVERSITY OF CÓRDOBA   (Spain)

^b Universidad de Cordoba   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL BENZOATE; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GONADORELIN; LUTEINIZING HORMONE; ONAPRISTONE; PROGESTERONE RECEPTOR; PROPIONITRILE; PYRAZOLE DERIVATIVE; TAMOXIFEN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ESTROGEN ACTIVITY; FEMALE; HORMONE RESPONSE; IMMUNOHISTOCHEMISTRY; LUTEINIZING HORMONE BLOOD LEVEL; LUTEINIZING HORMONE RELEASE; NEGATIVE FEEDBACK; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RADIOIMMUNOASSAY; RAT;

ANIMALS; CELL MEMBRANE; CELL NUCLEUS; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEEDBACK, BIOCHEMICAL; FEMALE; GONADOTROPHS; GONADOTROPIN-RELEASING HORMONE; GONANES; LIGANDS; LUTEINIZING HORMONE; NITRILES; OVARIECTOMY; PROGESTINS; PROPIONATES; PYRAZOLES; RATS; RATS, WISTAR; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; SELECTIVE ESTROGEN RECEPTOR MODULATORS; TAMOXIFEN;

EID: 34247392503     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/JOE-06-0214     Document Type: Article

References (54)

1. Arimura A & Schally AV 1971 Augmentation of pituitary responsiveness to LH-releasing hormone (LH-RH) by estrogen. Proceedings of the Society for Experimental Biology and Medicine 136 290-293.
2. Bellido C, Gonzalez D, Aguilar R & Sánchez-Criado JE 1999 Antiprogestins RU486 and ZK299 suppress basal and LHRH-stimulated FSH and LH secretion at pituitary level in the rat in an oestrous cycle stage-dependendent manner. Journal of Endocrinology 163 79-85.
3. Bellido C, Martín de las Mulas J, Tena-Sempere M, Aguilar R, Alonso R & Sánchez-Criado JE 2003 Tamoxifen induces gonadotropin-releasing hormone self-priming through an estrogen-dependent progesterone receptor expression in the gonadotrope of the rat. Neuroendocrinology 77 425-435.
4. Bellido C, Aguilar R, Alonso R, Garrido-Gracia JC & Sánchez-Criado JE 2005 Estradiol 17β blocks the estrogenic effect of tamoxifen on LH and PRL secretion in the rat. Journal of Physiology and Biochemistry 61 149-150.
5. Blaustein JD 2004 Minireview: neuronal steroid hormone receptors: they're not just for hormones anymore. Endocrinology 145 1075-1081.
6. Bression D, Michard M, Le Dafniet M, Pagesy P & Peillon F 1986 Evidence for a specific estradiol binding site on rat pituitary membranes. Endocrinology 119 1048-1051.
7. Byrne B, Fowler PA & Templeton A 1996 Role of progesterone and nonsteroidal ovarian factors in regulating gonadotropin-releasing hormone self-priming in vitro. Journal of Clinical Endocrinology and Metabolism 81 1454-1459.
8. 2)-treated, progesterone receptor knockout (PRKO) mice. Endocrinology 140 3653-3658.
9. Fink G 1988 Gonadotropin secretion and its control. In The Physiology of Reproduction, pp 1349-1377. Eds E Knobil & J Neill. New York: Raven Press.
10. Fink G 1995 The self-priming effect of LHRH: A unique servomechanism and possible cellular model for memory. Frontiers in Neuroendocrinology 16 183-190.
11. Fink G 2000 Neuroendocrine regulation of pituitary function. In Neuroendocrinology in Physiology and Medicine, pp 107-133. Eds PM Conn & ME Freeman. Totowa, NJ: Humana Press Inc..
12. Fox SR, Harlan RE, Shievers BD & Pfaff DW 1990 Chemical characterization of neuroendocrine targets for progesterone in the female rat brain and pituitary. Neuroendocrinology 51 276-283.
13. 131I-labeled human growth hormone of high specific radioactivity. Biochemical Journal 89 114-123.
14. Harms PG & Ojeda SR 1974 A rapid and simple procedure for chronic cannulation of the jugular vein. Journal of Applied Physiology 3 391-392.
15. Harrington WR, Sheng S, Barnett DH, Petz LN, Katzenellenbogen JA & Katzenellenbogen BS 2003 Activities of estrogen receptor alpha- and beta-selective ligands at diverse estrogen responsive gene sites mediating transactivation or transrepression. Molecular and Cellular Endocrinology 206 13-22.
16. Iwata J & Nishikaze O 1979 New micro-turbidimetric method for determination of protein in cerebrospinal fluid and urine. Clinical Chemistry 25 1317-1319.
17. Kelly MJ & Levin ER 2001 Rapid actions of plasma membrane estrogen receptors. Trends in Endocrinology and Metabolism 12 152-156.
18. Kuiper GC, Carlsson B, Grandien K, Enmark E, Haggblad J, Nilsson S & Gustafsson JA 1997 Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β. Endocrinology 138 863-870.
19. Legan SJ & Tsai H-W 2003 Oestrogen receptor-α and -β immunoreactivity in gonadotropin-releasing hormone neurones after ovariectomy and chronic exposure to oestradiol. Journal of Neuroendocrinology 15 1164-1179.
20. Levin ER 2001 Cell localization, physiology, and nongenomic actions of estrogen receptors. Journal of Applied Physiology 91 1860-1867.
21. Levin ER 2005 Integration of the extranuclear and nuclear actions of estrogen. Molecular Endocrinology 19 1951-1959.
22. Levine JE 1997 New concepts of the neuroendocrine regulation of gonadotropin surges in rats. Biology of Reproduction 56 293-302.
23. Levine JE, Chappell PE, Schneider JS, Sleiter NC & Szabo M 2001 Progesterone receptors as neuroendocrine integrators. Frontiers in Neuroendocrinology 22 69-106.
24. Lindzey J, Layes FL, Yates MM, Couse JF & Korach KS 2006 The bi-modal effects of estradiol on gonadotropin synthesis and secretion in female mice are dependent on estrogen receptor-α. Journal of Endocrinology 191 309-317.
25. McDonnell DP 1999 The molecular pharmacology of SERMs. Trends in Endocrinology and Metabolism 10 301-311.
26. McDonnell DP 2003 Mining the complexities of the estrogen signaling pathway for novel therapeutics. Endocrinology 144 4237-4240.
27. McDonnell DP, Connor CE, Wijayaratne A, Chang Ch-Y & Norris JD 2002 Definition of the molecular and cellular mechanism underlying the tissue-selective agonist/antagonist activities of selective estrogen receptor modulators. Recent Progress in Hormone Research 57 295-316.
28. Meyers MJ, Sun J, Carlson KE, Marriner A, Katzenellenbogen BS & Katzenellenbogen JA 2001 Estrogen receptor-β potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues. Journal of Medicinal Chemistry 44 4230-4251.
29. Mitchner NA, Garlic C & Ben-Jonathan N 1998 Cellular distribution and gene regulation of estrogen receptors α and β in the rat pituitary gland. Endocrinology 139 3976-3983.
30. Neef G, Beier S, Elger W, Henderson D & Wiechert R 1984 New steroid with antiprogestational and antiglucocorticoid activities. Steroids 44 349-372.
31. Pelletier G, Li S, Phaneuf D, Martel C & Labrie F 2003 Morphological studies of prolactin-secreting cells in estrogen receptor α and estrogen receptor β knockout mice. Neuroendocrinology 77 324-333.
32. Razandi M, Pedram A, Greene GL & Levin ER 1999 Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: studies of ERα and ERβ expressed in Chinese hamster ovary cells. Molecular Endocrinology 13 307-319.
33. Sánchez-Criado JE, Galiot F, Bellido C, González D & Tébar M 1993 Hypothalamus-pituitary-ovarian axis in cyclic rats lacking progesterone actions. Biology of Reproduction 48 916-925.
34. Sánchez-Criado JE, Guelmes O, Bellido C, González M, Hernández G, Aguilar R, Garrido-Gracia JC, Bello AR & Alonso R 2002 Tamoxifen but not other selective estrogen receptor modulators antagonizes estrogen actions on luteinizing hormone secretion while inducing gonadotropin-releasing hormone self-priming in the rat. Neuroendocrinology 76 203-213.
35. Sánchez-Criado JE, Martín de las Mulas J, Bellido C, Tena-Sempere M, Aguilar R & Blanco A 2004 Biological role of pituitary estrogen receptors ERα and ERβ on progesterone receptor expression and action and on gonadotropin and prolactin secretion in the rat. Neuroendocrinology 79 247-258.
36. Sánchez-Criado JE, Martín de las Mulas J, Bellido C, Aguilar R & Garrido-Gracia JC 2005a Gonadotroph oestrogen receptor-α and -β and progesterone receptor immunoreactivity after ovariectomy and exposure to oestradiol benzoate, tamoxifen or raloxifene in the rat: correlation with LH secretion. Journal of Endocrinology 184 59-68.
37. Sánchez-Criado JE, Bellido C, Aguilar R & Garrido-Gracia JC 2005b A paradoxical inhibitory effect of oestradiol-17β on GnRH self-priming in pituitaries from tamoxifen-treated rats. Journal of Endocrinology 186 43-49.
38. Sánchez-Criado JE, Martín de las Mulas J, Bellido C, Navarro VM, Aguilar R, Garrido-Gracia JC, Malagón MM, Tena-Sempere M & Blanco A 2006a Gonadotropin secreting cells in ovariectomized rats treated with different oestrogen receptor (ER) ligands: a modulatory role for ERβ in the gonadotrope? Journal of Endocrinology 188 167-177.
39. Sánchez-Criado JE, Garrido-Gracia JC, Bellido C, Aguilar R, Guelmes P, Abreu P, Alonso R, Barranco I, Millán Y & Martín de las Mulas J 2006b Oestradiol-17β inhibits tamoxifen-induced LHRH self-priming blocking hormone-dependent and ligand-independent activation of the gonadotrope progesterone receptor in the rat. Journal of Endocrinology 190 73-84.
40. Schmidt BMW, Gerdes D, Feuring M, Falkenstein E, Christ M & Wehling M 2000 Rapid, nongenomic steroid actions: a new age? Frontiers in Neuroendocrinology 21 57-94.
41. Schuiling GA, Valkhof N & Koiter TR 1999 FSH inhibits the augmentation by oestradiol of the pituitary responsiveness to GnRH in the female rat. Human Reproduction 14 21-26.
42. Schwartz NB 2000 Neuroendocrine regulation of reproductive cyclicity. In Neuroendocrinology in Physiology and Medicine, pp 135-145. Eds PM Conn & ME Freeman. Totowa, NJ: Humana Press Inc.
43. Simoncini T & Genazzani AR 2003 Non-genomic actions of sex steroid hormones. European Journal of Endocrinology 148 281-292.
44. Smith CL & O'Malley BW 2004 Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocrine Reviews 25 45-71.
45. Stauffer SR, Coletta CJ, Tedesco R, Nishiguchi G, Carlson K, Sun J, Katzenellenbogen BS & Katzenellenbogen JA 2000 Pyrazole ligands: structure-affinity/activity relationships and estrogen receptor-α-selective agonist. Journal of Medicinal Chemistry 43 4934-4947.
46. Sun J, Huang YR, Harrington WR, Sheng S, Katzenellenbogen JA & Katzenellenbogen BS 2002 Antagonists selective for estrogen receptor α. Endocrinology 143 941-947.
47. Toran-Allerand CD 2004 Minireview: a pletora of estrogen receptors in the brain: where will it end? Endocrinology 145 1069-1074.
48. Toran-Allerand CD, Singh M & Sétáló G 1999 Novel mechanism of estrogen action in the brain: new players in an old story. Frontiers in Neuroendocrinology 20 97-121.
49. Turgeon JL & Waring DW 1991 The timing of progesterone-induced ribonucleic acid and protein synthesis for augmentation of luteinizing hormone secretion. Endocrinology 129 3234-3239.
50. Turgeon JL & Waring DW 1994 Activation of the progesterone receptor by the gonadotropin-releasing hormone self priming signaling pathway. Molecular Endocrinology 8 860-869.
51. Tzuckerman MT, Esty A, Santiso-Mere D, Danielian P, Parker MG, Stein RB, Pike J & McDonnell DP 1994 Human estrogen receptor transcriptional capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions. Molecular Endocrinology 8 21-30.
52. Vaillant C, Chesnel F, Schausi D, Tiffoche C & Thieulant ML 2002 Expression of estrogen receptor subtypes in rat pituitary gland during pregnancy and lactation. Endocrinology 134 4249-4258.
53. Waring DW & Turgeon JL 1980 Luteinizing hormone-releasing hormone-induced luteinizing hormone secretion in vitro: cyclic changes in responsiveness and self-priming. Endocrinology 106 1430-1436.
54. Waring DW & Turgeon JL 1992 A pathway for luteinizing hormone-releasing hormone self-potentiation: cross-talk with the progesterone receptor. Endocrinology 130 3275-3282.