Antibacterial activity of bovine lactoferrin hydrolysate against mastitis pathogens and its effect on superoxide production of bovine neutrophils

Zoonoses and Public Health

Volumn 54, Issue 3-4, 2007, Pages 160-164

  Kawai, K ^a,d   Shimazaki, K ^b   Higuchi, H ^c   Nagahata, H ^c  

^a Seibu Veterinary Clinical Center   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c RAKUNO GAKUEN UNIVERSITY   (Japan)

^d NONE   (Japan)

Author keywords

Antibacterial activity; Lactoferrin; Lactoferrin hydrolysate; Mastitis causing pathogens; Neutrophils; O2 production

Indexed keywords

ANTIINFECTIVE AGENT; LACTOFERRIN; PROTEIN HYDROLYSATE; SUPEROXIDE;

ANIMAL; ARTICLE; BACTERIUM; CATTLE; CATTLE DISEASE; DOSE RESPONSE; DRUG EFFECT; FEMALE; FUNGUS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MILK; NEUTROPHIL;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIA; CATTLE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FUNGI; LACTOFERRIN; MASTITIS, BOVINE; MICROBIAL SENSITIVITY TESTS; MILK; NEUTROPHILS; PROTEIN HYDROLYSATES; SUPEROXIDES;

BOS; BOVINAE; ENTEROCOCCUS; ESCHERICHIA COLI; FUNGI; KLEBSIELLA PNEUMONIAE; PROTOTHECA ZOPFII; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS;

EID: 34247372268     PISSN: None     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1863-2378.2007.01031.x     Document Type: Article

References (26)

1. Anderson, B. F., H. M. Baker, G. E. Norris, D. W. Rice E. N. Baker, 1989: Structure of human lactoferrin: crystallographic structure analysis and refinement at 2.8 A resolution. J. Mol. Biol. 209, 711 734.
2. Arnold, R. R., M. Brewer J. J. Gauthier, 1980: Bactericidal activity of human lactoferrin sensitivity of a variety of microorganisms. Infect. Immun. 28, 893 898.
3. Bellamy, W., M. Takase, H. Wakabayashi, K. Kawase M. Tomita, 1992: Antibacterial spectrum of lactoferrin B, a potent bactericidal peptide derinered from the N-terminal region of bovine lactoferrin. J. Appl. Bacteriol. 73, 472 479.
4. Bramley, A. J., J. S. Cullor, R. J. Erskine, L. K. Fox, R. J. Harmon, J. S. Hogan, S. C. Nickerson, S. P. Oliver, K. L. Smith L. M. Sordillo, 1996: Current Concepts of Bovine Mastitis, 4th edn. National Mastitis Council Inc., Madison, WI, USA.
5. Brock, J. H., 2002: The physiology of lactoferrin. Biochem. Cell Biol. 80, 1 6.
6. Ellison R. T. III., 1994: The effects of lactoferrin on gram-negative bacteria. Adv. Exp. Med. Biol. 357, 71 90.
7. Farnaud, S. R. W. Evans, 2003: Lactoferrin - a multifunctional protein with antimicrobial properties. Mol. Immunol. 40, 395 405.
8. Frank, N., L. C. Ferguson, R. F. Cross D. R. Redman, 1969: Prototheca, a cause of bovine mastitis. Am. J. Vet. Res. 30, 1785 1794.
9. Gray-Owen, S. D. A. B. Schryvers, 1996: Bacterial transferrin and lactoferrin receptors. Trends Microbiol. 4, 185 191.
10. Harmon, R. J., F. L. Schanbacher, L. C. Ferguson K. L. Smith, 1976: Changes in lactoferrin, immunoglobulin G, bovine serum albumin, and alpha-lactalbumin during acute experimental and natural coliform mastitis in cows. Infect. Immun. 13, 533 542.
11. Higuchi, H. H. Nagahata, 1998: Comparison of superoxide production, protein kinase C and tyrosine kinase activities in neutrophils from neonatal calves and cows. Res. Vet. Sci. 65, 139 143.
12. Hogan, J. S., R. N. González, R. J. Harmon, S. C. Nickerson, S. P. Oliver, J. W. Pankey K. L. Smith, 1999: Laboratory Handbook on Bovine Mastitis, Revised Edn. National Mastitis Council Inc., Madison, WI, USA.
13. van Hooijdonk, A. C., K. D. Kussendrager J. M. Steijns, 2000: In vivo antimicrobial and antiviral activity of components in bovine milk and colostrum involved in non-specific defence. Br. J. Nutr. 84 (Suppl. 1 0S127 134.
14. Kawai, K., S. Hagiwara, A. Anri H. Nagahata, 1999: Lactoferrin concentration in milk of bovine clinical mastitis. Vet. Res. Commun. 23, 391 398.
15. Kawai, K., H. Nagahata, N. Y. Lee, A. Anri K. Shimazaki, 2003: Effect of infusing lactoferrin hydrolysate into bovine mammary glands with subclinical mastitis. Vet. Res. Commun. 27, 539 548.
16. Kimura, M., M. S. Nam, Y. Oukouchi, H. Kumura, K. Shimazaki D. Y. Yu, 2000: Antimicrobial peptide of korean native goat lactoferrin and identification of the part essential for this activity. Biochem. Biophys. Res. Commun. 268, 333 336.
17. Kirkpatrick, C. H., I. Green, R. R. Rich A. L. Schade, 1971: Inhibition of growth of Candida albicans by iron-unsaturated lactoferrin: relation to host-defense mechanisms in chronic mucocutaneous candidiasis. J. Infect. Dis. 124, 539 544.
18. Lee, N. Y., K. Kawai, I. Nakamura, T. Tanaka, H. Kumura K. Shimazaki, 2004: Susceptibilities against bovine lactoferrin with microorganisms isolated from mastitic milk. J. Vet. Med. Sci. 66, 1267 1269.
19. Masson, P. L. J. F. Heremans, 1971: Lactoferrin in milk from different species. Comp. Biochem. Physiol. B. 39, 119 129.
20. Modun, B., J. Morrissey P. Williams, 2000: The staphylococcal transferrin receptor: a glycolytic enzyme with novel functions. Trends Microbiol. 8, 231 237.
21. Murdock, C. A. K. R. Matthews, 2002: Antibacterial activity of pepsin-digested lactoferrin on foodborne pathogens in buffered broth systems and ultra-high temperature milk with EDTA. J. Appl. Microbiol. 93, 850 856.
22. Nagahata, H., M. E. J. R. Kehrli, H. Murata, H. Okada G. J. Kociba, 1994: Neutrophil function and pathologic findings in Holstein calves with leukocyte adhesion deficiency. Am. J. Vet. Res. 55, 40 48.
23. Naidu, A. S., M. Andersson, J. Miedzobrodzki, A. Forsgren J. L. Watts, 1991: Bovine lactoferrin receptors in Staphylococcus aureus isolated from bovine mastitis. J. Dairy Sci. 74, 1218 1226.
24. Sanchez, M. S. J. L. Watts, 1999: Enhancement of the activity of novobiocin against Escherichia coli by lactoferrin. J. Dairy Sci. 82, 494 499.
25. Schalm, O. W. G. M. Woods, 1952: Characteristics of coliform mastitis and treatment with dihydrostreptomycin. J. Am. Vet. Med. Assoc. 120, 385 388.
26. Tomita, M., W. Bellamy, M. Takase, K. Yamauchi, H. Wakabayashi K. Kawase, 1991: Potent antibacterial peptides generated by pepsin digestion of bovine lactoferrin. J. Dairy Sci. 74, 4137 4142.