Gastric epithelial cell proliferation and cagA status in Helicobacter pylori gastritis at different gastric sites

Scandinavian Journal of Gastroenterology

Volumn 42, Issue 5, 2007, Pages 545-554

  Cabral, Mônica M D A ^a   Oliveira, Celso A ^a   Mendes, Cläudia M C ^c   Guerra, Juliana ^b   Queiroz, Dulciene M M ^b   Rocha, Gifone A ^b   Rocha, Andreia M C ^b   Nogueira, Ana M M F ^a,c  

^a Faculty of Medicine   (Brazil)

^b Faculty of Medicine   (Brazil)

^c FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

cagA status; Epithelial proliferation; Gastritis; Helicobacter pylori; Topography

Indexed keywords

CAGA PROTEIN; KI 67 ANTIGEN;

ADULT; AGED; ARTICLE; ATROPHIC GASTRITIS; BACTERIAL STRAIN; CELL PROLIFERATION; FEMALE; GASTRITIS; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; INFLAMMATORY INFILTRATE; INTESTINE METAPLASIA; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEROLOGY; STOMACH ANTRUM; STOMACH BIOPSY; STOMACH CARCINOGENESIS; STOMACH EPITHELIUM; STOMACH MUCOSA; STOMACH PH;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BIOPSY; CELL PROLIFERATION; DNA, BACTERIAL; EPITHELIAL CELLS; FEMALE; GASTRIC MUCOSA; GASTRITIS; GENE EXPRESSION; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; SEVERITY OF ILLNESS INDEX;

EID: 34247366806     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.1080/00365520601014034     Document Type: Article

References (38)

1. Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1984;8390:1311-5.
2. Correa P. Human gastric carcinogenesis: a multistep and multifactorial process. First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. Cancer Res 1992;52:6735-40.
3. Correa P. Helicobacter pylori and gastric carcinogenesis. Am J Surg Pathol ;19 Suppl 1995;1:S37-43.
4. International Agency for Research on Cancer (IARC)/WHO. Infection with Helicobacter pylori. In: Schistosomes, liver flukes and Helicobacter pylori. Evaluation of carcinogenic risk to humans. IARC Monograph 1994;177-202.
5. Brenes F, Ruiz B, Correa P, Hunter F, Rhamakrishnan T, Fontham E, et al. Helicobacter pylori causes hyperproliferation of the gastric epithelium: pre- and post-eradication indices of proliferating cell nuclear antigen. Am J Gastroenterol 1993;88:1870-5.
6. Cahill RJ, Xia H, Kilgallen C, Beattie S, Hamilton H, O'Morain C. Effect of eradication of Helicobacter pylori infection on gastric epithelial cell proliferation. Dig Dis Sci 1995;/40:1627-31.
7. Lynch DAF, Mapstone NP, Clarke AMT, Sobala GM, Jackson P, Morrison L, et al. Cell proliferation in Helicobacter pylori associated gastritis and the effect of eradication therapy. Gut 1995;36:346-50.
8. Bechi P, Balzi M, Becciolini A, Maugeri A, Raggi CC, Amorosi A, et al. Helicobacter pylori and cell proliferation of the gastric mucosa: possible implications for gastric carcinogenesis. Am J Gastroenterol 1996;91:271-6.
9. Fan XG, Kelleher D, Fan XJ, Xia HX, Keeling PWN. Helicobacter pylori increases proliferation of gastric epithelial cells. Gut 1996;38:19-22.
10. Moss SF, Calam J, Agarwal B, Wang S, Holt PR. Induction of gastric epithelial apoptosis by Helicobacter pylori. Gut 1996;38:498-501.
11. Panella C, Ierardi E, Polimeno L, Balzano T, Ingrosso M, Amoruso A, et al. Proliferative activity of gastric epithelium in progressive stages of Helicobacter pylori infection. Dig Dis Sci 1996;41:1132-8.
12. Murakami K, Fujioka T, Kodama R, Kubota T, Tokieda M, Nasu M. Helicobacter pylori infection accelerates human gastric mucosal cell proliferation. J Gastroenterol 1997;2:184-8.
13. + strains and dissociation of gastric epithelial cell proliferation from apoptosis. J Natl Cancer Inst 1997;89:863-8.
14. Wagner S, Beil W, Westermann J, Logan RPH, Bock CT, Trautwein C, et al. Regulation of gastric epithelial cell growth by Helicobacter pylori: evidence for a major role of apoptosis. Gastroenterology 1997;113:1836-47.
15. Rokkas T, Ladas S, Liatsos C, Petridou E, Papatheodorou G, Theocharis S, et al. Relationship of Helicobacter pylori CagA status to gastric cell proliferation and apoptosis. Dig Dis Sci 1999;44:487-93.
16. Jang TJ, Kim JR. Proliferation and apoptosis in gastric antral epithelial cells of patients infected with Helicobacter pylori. J Gastroenterol 2000;35:265-71.
17. Xia HHX, Talley NJ. Apoptosis in gastric epithelium induced by Helicobacter pylori: implications in gastric carcinogenesis. Am J Gastroenterol 2001;96:16-26.
18. Kitsanta P, Triantafyllou K, Chatziargyriou M, Barbatzas C, Ladas SD. Gastric mucosa epithelial cell kinetics are differentiated by anatomic site and Helicobacter pylori infection. Dig Dis Sci 2005;50:1087-91.
19. Normark S, Nilsson C, Normark BH, Hornef MW. Persistent infection with Helicobacter pylori and the development of gastric cancer. Adv Cancer Res 2003;90:63-89.
20. Penta R, De Falco M, Iaquinto G, De Luca A. Helicobacter pylori and gastric epithelial cells: from gastritis to cancer. J Exp Clin Can Res 2005;24:337-45.
21. Nardone G, Staibano S, Rocco A, Mezza E, D'Armiento FPD, Insabato L, et al. Effect of Helicobacter pylori infection and its eradication on cell proliferation, DNA status, and oncogene expression in patients with chronic gastritis. Gut 1999;44:789-99.
22. Leodolter A, Naumann M, Malfertheiner P. Prevention of gastic cancer by Helicobacter pylori eradication. Dig Dis 2004;22:313-9.
23. Peek RM, Jr, Blaser MJ, Mays DJ, Forsyth MH, Cover TL, Song SY, et al. Helicobacter pylori strain-specific genotypes and modulation of the gastric epithelial cell cycle. Cancer Res 1999;59:6124-31.
24. Lynch DA, Mapstone NP, Clarke AM, Jackson P, Moayyedi P, Dixon MF, et al. Correlation between epithelial cell proliferation and histological grading in gastric mucosa. J Clin Pathol 1999;52:367-71.
25. Tsujii M, Kawano S, Tsujii S, Takei Y, Tamura K, Fusamoto H, et al. Mechanism for ammonia-induced promotion of gastric carcinogenesis in rats. Carcinogenesis 1995;16:563-6.
26. Kim H. Oxidative stress in Helicobacter pylori -induced gastric cell injury. Inflammopharmacology 2005;13:63-74.
27. Scotiniotis IA, Rokkas T, Furth EE, Rigas B, Shiff SJ. Altered gastric epithelial cell kinetics in Helicobacter pylori-associated intestinal metaplasia: implications for gastric carcinogenesis. Int J Cancer 2000;85:192-200.
28. Xia HHX, Zhang G-S, Talley NJ, Wong BCY, Yang Y, Henwood C, et al. Topographic association of gastric epithelial expression of Ki-67, Bax and Bcl-2 with antralization in the gastric incisura, body and fundus. Am J Gastroenterol 2002;97:3023-31.
29. Queiroz DMM, Mendes EN, Rocha GA. Indicator medium for isolation of Campylobacter pylori. J Clin Microbiol 1987;25:2378-9.
30. Peek RM, Jr, Miller GG, Tham KT, Pérez-Pérez GI, Cover TL, Atherton JC, et al. Detection of Helicobacter pylori gene expression in human gastric mucosa. J Clin Microbiol 1995;33:28-32.
31. Clayton CL, Kleanthous H, Coates PJ, Morgan DD, Tabaqchali S. Sensitive detection of Helicobacter pylori by using polymerase chain reaction. J Clin Microbiol 1992;30:192-200.
32. Rocha GA, Oliveira AMR, Queiroz DMM, Carvalho AST, Nogueira AMMF. Immunoblot analysis of humoral immune response to Helicobacter pylori in children with and without duodenal ulcer. J Clin Microbiol 2000;38:1777-81.
33. Rocha GA, Queiroz DMM, Mendes EN, Lage AP, Barbosa AJA. Simple carbolfuchsin staining for showing Campylobacter pylori and other spiral bacteria in gastric mucosa. J Clin Pathol 1989;42:1004-5.
34. Dixon MF, Genta RM, Yardley JH, Correa P. Classification and grading of gastritis: the updated Sydney System. Am J Surg Pathol 1996;20:1161-81.
35. Hsu SM, Raine L, Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 1981;29:577-80.
36. Crabtree JE, Kersulyte D, Li SD, Lindley IJ, Berg DE. Modulation of Helicobacter pylori induced interleukin-8 synthesis in gastric epithelial cells mediated by cag PAI encoded VirD4 homologue. J Clin Pathol 1999;52:653-7.
37. Cabral MMDA, Mendes CMC, Castro LPF, Cartelle CT, Guerra J, Queiroz DMM, et al. Apoptosis in Helicobacter pylori gastritis is related to cagA status. Helicobacter 2006;11:469-76.
38. Blaser MJ, Perez-Perez GI, Kleanthous H, Cover TL, Peek RM, Chyou PH, et al. Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res 1995;55:2111-5.