Novel morpholin-3-one derivatives induced apoptosis and elevated the level of P53 and Fas in A549 lung cancer cells

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 11, 2007, Pages 3889-3895

  He, Qiuxia ^a,b   Zhu, Xingshang ^a,b   Shi, Mei ^a,b   Zhao, Baoxiang ^a   Zhao, Jing ^a,b   Zhang, Shangli ^a,b   Miao, Junying ^a,b  

^a SHANDONG UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

A549 lung cancer cell; Apoptosis; Fas; Morpholin 3 one derivate; P53

Indexed keywords

4 (4 CHLOROPHENYL) 6 [(4 NITROPHENOXY)METHYL]MORPHOLIN 3 ONE; 6 (4 CHLOROPHENOXY) 4 (4 METHOXYPHENYL)MORPHOLIN 3 ONE; 6 [(4 NITROPHENOXY)METHYL] 4 PHENYLMORPHOLIN 3 ONE; ANTINEOPLASTIC AGENT; FAS ANTIGEN; MORPHOLINE DERIVATIVE; PROTEIN P53; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER GROWTH; CELL CYCLE G1 PHASE; CELL CYCLE REGULATION; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LUNG CANCER;

ANTIGENS, CD95; APOPTOSIS; G1 PHASE; HUMANS; LUNG NEOPLASMS; MORPHOLINES; NITRO COMPOUNDS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 34247335043     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.03.008     Document Type: Article

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