Can loss of apoptosis protect against cancer?

Trends in Genetics

Volumn 23, Issue 5, 2007, Pages 232-237

  Wodarz, Dominik ^a   Komarova, Natalia ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER PREVENTION; CANCER SURVIVAL; CARCINOGENESIS; CELL DEATH; CELL DIVISION; CELL MUTANT; HUMAN; KIDNEY CARCINOMA; MORTALITY; PANCREAS CANCER; PRIORITY JOURNAL; TUMOR VOLUME;

ANIMALS; APOPTOSIS; HUMANS; KINETICS; MODELS, BIOLOGICAL; MUTATION; NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 34247327415     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tig.2007.03.005     Document Type: Article

References (35)

1. Kinzler K.W., and Vogelstein B. The Genetic Basis of Human Cancer (1998), McGraw-Hill
2. Wodarz D. Editorial. Semin. Cancer Biol. 15 (2005) 421-422
3. Boland C.R., and Goel A. Somatic evolution of cancer cells. Semin. Cancer Biol. 15 (2005) 436-450
4. Macleod K. Tumor suppressor genes. Curr. Opin. Genet. Dev. 10 (2000) 81-93
5. Vogelstein B., et al. Surfing the p53 network. Nature 408 (2000) 307-310
6. Jaattela M. Multiple cell death pathways as regulators of tumour initiation and progression. Oncogene 23 (2004) 2746-2756
7. Kroemer G., and Martin S.J. Caspase-independent cell death. Nat. Med. 11 (2005) 725-730
8. Nowell P.C. The clonal evolution of tumor cell populations. Science 194 (1976) 23-28
9. Dewanji A., et al. A generalized Luria-Delbrück model. Math. Biosci. 197 (2005) 140-152
10. Komarova N.L., and Wodarz D. Drug resistance in cancer: principles of emergence and prevention. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 9714-9719
11. Folkman J., and Kalluri R. Cancer without disease. Nature 427 (2004) 787
12. Volpe A., et al. The natural history of incidentally detected small renal masses. Cancer 100 (2004) 738-745
13. Folkman J. Role of angiogenesis in tumor growth and metastasis. Semin. Oncol. 29 (2002) 15-18
14. Kemp C.J., et al. Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors. Cell 74 (1993) 813-822
15. Blagosklonny M.V. p53: an ubiquitous target of anticancer drugs. Int. J. Cancer 98 (2002) 161-166
16. Oren M. Decision making by p53: life, death and cancer. Cell Death Differ. 10 (2003) 431-442
17. Shih I.M., et al. Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis. Cancer Res. 61 (2001) 818-822
18. Komarova N.L., and Wodarz D. The optimal rate of chromosome loss for the inactivation of tumor suppressor genes in cancer. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 7017-7021
19. Motzer R.J., et al. Renal-cell carcinoma. New Engl. J. Med. 335 (1996) 865-875
20. Rathmell W.K., et al. Renal cell carcinoma. Curr. Opin. Oncol. 17 (2005) 261-267
21. Ozono S., et al. Tumor doubling time of renal cell carcinoma measured by CT: collaboration of Japanese Society of Renal Cancer. Jpn. J. Clin. Oncol. 34 (2004) 82-85
22. Bosniak M.A. Observation of small incidentally detected renal masses. Semin. Urol. Oncol. 13 (1995) 267-272
23. Oda T., et al. Growth rates of primary and metastatic lesions of renal cell carcinoma. Int. J. Urol. 8 (2001) 473-477
24. Bardeesy N., and DePinho R.A. Pancreatic cancer biology and genetics. Nat. Rev. Cancer 2 (2002) 897-909
25. Leach S.D. Mouse models of pancreatic cancer: the fur is finally flying!. Cancer Cell 5 (2004) 7-11
26. Rosenberg L. Pancreatic cancer: a review of emerging therapies. Drugs 59 (2000) 1071-1089
27. Hingorani S.R., et al. Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell 4 (2003) 437-450
28. Luria S.E., and Delbrück M. Mutations of bacteria from virus sensitivity to virus resistance. Genetics 28 (1943) 491-511
29. Lea D.E., and Coulson C.A. The distribution of the numbers of mutants in bacterial populations. J. Genet. 49 (1949) 264-285
30. Zheng Q. Progress of a half century in the study of the Luria-Delbrück distribution. Math. Biosci. 162 (1999) 1-32
31. Angerer W.P. An explicit representation of the Luria-Delbrück distribution. J. Math. Biol. 42 (2001) 145-174
32. Stewart F.M., et al. Fluctuation analysis: the probability distribution of the number of mutants under different conditions. Genetics 124 (1990) 175-185
33. Natarajan L., et al. Estimation of spontaneous mutation rates. Biometrics 59 (2003) 555-561
34. Frank S.A. Somatic mosaicism and cancer: inference based on a conditional Luria-Delbrück distribution. J. Theor. Biol. 223 (2003) 405-412
35. Iwasa Y., et al. Evolution of resistance during clonal expansion. Genetics 172 (2006) 2557-2566