Control of human herpes virus type 8 - Associated diseases by NK cells

Annals of the New York Academy of Sciences

Volumn 1096, Issue , 2007, Pages 37-43

  Sirianni, Maria C ^a   Campagna, Massimo ^a   Scaramuzzi, Donato ^a   Carbonari, Maurizio ^a   Toschi, Elena ^b   Bacigalupo, Ilaria ^b   Monini, Paolo ^b   Ensoli, Barbara ^b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

Human herpes virus type 8; MHC I; NK cells; Oncogenic virus; Receptors

Indexed keywords

GRANZYME A; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PERFORIN; HLA ANTIGEN CLASS 1;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; AIDS RELATED EFFUSION LYMPHOMA; ANTIGEN EXPRESSION; CELL COUNT; CONFERENCE PAPER; CYTOLYSIS; CYTOTOXICITY; DISEASE SEVERITY; DOWN REGULATION; HUMAN HERPESVIRUS 8; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; KAPOSI SARCOMA; LYMPHOMA; MAJOR HISTOCOMPATIBILITY COMPLEX; NATURAL KILLER CELL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; T LYMPHOCYTE; ARTICLE; CYTOTOXIC T LYMPHOCYTE; GENE EXPRESSION REGULATION; HERPES VIRUS INFECTION; HUMAN; IMMUNE SYSTEM; IMMUNOLOGY; METABOLISM; MONONUCLEAR CELL; SIGNAL TRANSDUCTION; VIROLOGY;

HUMAN HERPESVIRUS 8; HUMAN IMMUNODEFICIENCY VIRUS; SIMPLEXVIRUS;

CYTOTOXICITY, IMMUNOLOGIC; GENE EXPRESSION REGULATION; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 8, HUMAN; HISTOCOMPATIBILITY ANTIGENS CLASS I; HIV INFECTIONS; HUMANS; IMMUNE SYSTEM; KILLER CELLS, NATURAL; LEUKOCYTES, MONONUCLEAR; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; T-LYMPHOCYTES, CYTOTOXIC;

EID: 34247227599     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1397.068     Document Type: Conference Paper

References (14)

1. MORETTA, L., C. BOTTINO, D. PENDE, et al. 2002. Human natural killer cells: their origin, receptors and function. Eur. J. Immunol. 32: 1205-1211.
2. CHANG, Y., E. CESARMAN, M.S. PESSIN, et al. 1994. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 266: 1865-1869.
3. NADOR, R.G., E. CESARMAN, D.M. KNOWLES & J.W. SAID. 1995. Herpes-like DNA sequences in a body-cavity-based lymphoma in an HIV-negative patient. N. Engl. J. Med. 333: 943-943.
4. ENSOLI, B., C. SGADARI, G. BACILLARI, et al. 2001. Biology of Kaposi's sarcoma. Eur. J. Cancer 37: 1251-1269.
5. FAUCI, A.S., D. MAVILIO & S. KOTTILIL. 2005. NK cells in HIV infection: paradigm for protection or targets for ambush. Nat. Rev. Immunol. 5: 835-843.
6. SIRIANNI, M.C., F. ENSOLI, C. ALARIO, et al. 2001. Distribution of the natural killer-related receptor for HLA-C during highly active antiretroviral therapy for human immunodeficiency virus infection. Hum. Immunol. 62: 1328-1334. Erratum in: Hum. Immunol. 2002; 63: 336-336.
7. DUPIN, N., C. FISHER, P. KELLAM, et al. 1999. Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma. Proc. Natl. Acad. Sci. USA 96: 4546-4551.
8. SGADARI, C., G. BARILLARI, E. TOSCHI, et al. 2002. HIV protease inhibitors are potent anti-angiogenic molecules and promote regression of Kaposi sarcoma. Nat. Med. 8: 225-232.
9. LEBBÈ, C., L. BLUM, C. PELLET, et al. 1998. Clinical and biological impact of antiretroviral therapy with protease inhibitors on HIV-related Kaposi's sarcoma. AIDS 12: 45-49.
10. COSCOY, L. & D. GANEM. 2000. Kaposi's sarcoma-associated herpesvirus encodes two proteins that block cell surface display of MHC class I chains by enhancing their endocytosis. Proc. Natl. Acad. Sci. USA 97: 8051-8056. Erratum in Proc. Natl. Acad. Sci. USA 98: 2111-2111.
11. COSCOY, L. & D. GANEM. 2001. A viral protein that selectively downregulates ICAM-1 and B7-2 and modulates T cell costimulation. J. Clin. Invest. 107: 1599-1606.
12. SIRIANNI, M.C., L. VINCENZI, S. TOPINO, et al. 2002. NK cell activity controls human herpesvirus 8 latent infection and is restored upon highly active antiretroviral therapy in AIDS patients with regressing Kaposi's sarcoma. Eur. J. Immunol. 32: 2711-2720.
13. MONINI, P., M.C. SIRIANNI, M. FRANCO, et al. 2001. Clearance of human herpesvirus 8 from blood and regression of leukopenia-associated aggressive classic Kaposi's sarcoma during interferon-alpha therapy: a case report. Clin. Infect. Dis. 33: 1782-1785.
14. SIRIANNI, M.C., F. LIBI, M. CAMPAGNA, et al. 2005. Down-regulation of the major histocompatibility complex class I molecules by human herpesvirus type 8 and impaired natural killer cell activity in primary effusion lymphoma development. Br. J. Haematol. 130: 92-95.