Clearance of human herpesvirus 8 from blood and regression of leukopenia-associated aggressive classic Kaposi's sarcoma during interferon-α therapy: A case report

Clinical Infectious Diseases

Volumn 33, Issue 10, 2001, Pages 1782-1785

  Monini, P ^a   Sirianni, M C ^c   Franco, M ^a   Vincenzi, L ^c   Topino, S ^c   Goletti, D ^e   Leone, P ^a,a   Chiozzini, C ^a   Nicastri, E ^f   Andreoni, M ^f   Borduagni, O ^d   Sgadari, C ^a   Rezza, G ^b   Sturzl M ^g   Ensoli, B ^a  

^a Institute of Virology   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^c Department of Clinical Medicine ^*  (Italy)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

^e Istituto di Ricovero e Cura a Caraterre Scientifico L   (Italy)

^f UNIVERSITY OF ROME TOR VERGATA   (Italy)

^g INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2B INTERFERON; CD3 ANTIGEN; CD4 ANTIGEN;

ARTICLE; CASE REPORT; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HUMAN; HUMAN HERPESVIRUS 8; HUMAN IMMUNODEFICIENCY VIRUS; KAPOSI SARCOMA; LEUKOPENIA; LYMPHOCYTE COUNT; NONHUMAN; PRIORITY JOURNAL; REMISSION; VIREMIA; VIRUS INHIBITION;

ANTIVIRAL AGENTS; DNA, VIRAL; FEMALE; HERPESVIRUS 8, HUMAN; HIV SERONEGATIVITY; HUMANS; INTERFERON ALFA-2B; LEUKOPENIA; SARCOMA, KAPOSI; TREATMENT OUTCOME;

EID: 0035889457     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/323982     Document Type: Article

References (10)

1. Reactivation and persistence of human herpesvirus-8 infection in B cells and monocytes by Th-1 cytokines increased in Kaposi's sarcoma
2. Detection of Kaposi's sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi's sarcoma
3. Kaposi's sarcoma: A result of the interplay among inflammatory cytokines, angiogenic factors and viral agents
4. Clinical and biological impact of antiretroviral therapy with protease inhibitors on HIV-related Kaposi's sarcoma
5. Synergy between basic fibroblast growth factor and human immunodeficiency virus type 1 Tat protein in induction of Kaposi's sarcoma
6. Clearance of human herpesvirus type 8 viraemia in HIV-1-positive patients with Kaposi's sarcoma treated with liposomal doxorubicin
7. Non-AIDS-associated Kaposi's sarcoma (classical and endemic African types): Treatment with low doses of recombinant interferon-α
8. Long-term follow-up of non-HIV Kaposi's sarcoma treated with low-dose recombinant interferon α-2b
9. α-interferon inhibits human herpesvirus 8 (HHV-8) reactivation in primary effusion lymphoma cells and reduces HHV-8 load in cultured peripheral blood mononuclear cells
10. Non-human immunodeficiency virus Kaposi's sarcoma can be effectively treated with low-dose interferon-α despite the persistence of herpesvirus-8