Synthesis and biological evaluation of chiral α-aminoanilides with central antinociceptive activity

Journal of Medicinal Chemistry

Volumn 50, Issue 8, 2007, Pages 1907-1915

  Corbo, Filomena ^a   Franchini, Carlo ^a   Lentini, Giovanni ^a   Muraglia, Marilena ^a   Ghelardini, Carla ^b   Matucci, Rosanna ^b   Galeotti, Nicoletta ^b   Vivoli, Elisa ^b   Tortorella, Vincenzo ^a  

^a UNIVERSITY OF BARI   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYL GROUP; AMIDE; AMINE; ANILIDE; METHYL GROUP; TOCAINIDE;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CHIRALITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG SCREENING; DRUG SYNTHESIS; ENANTIOSELECTIVITY; HOT PLATE TEST; HYDROGEN BOND; IN VIVO STUDY; LICKING; LIPOPHILICITY; MOTOR COORDINATION; MOUSE; NONHUMAN; OPTICAL ROTATION; PAIN THRESHOLD; ROTAROD TEST; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION;

ANALGESICS; ANILIDES; ANIMALS; HYDROGEN BONDING; MALE; MICE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; VALINE;

EID: 34247218073     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm061078e     Document Type: Article

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