Pancreatic cellular injury after cardiac surgery with cardiopulmonary bypass: Frequency, time course and risk factors

Shock

Volumn 27, Issue 5, 2007, Pages 474-481

  Nys, Monique ^a,b   Venneman, Ingrid ^a   Deby Dupont, Ginette ^a,b   Preiser, Jean Charles ^a,b   Vanbelle, Sophie ^b   Albert, Adelin ^b   Camus, Gérard ^b   Damas, Pierre ^a   Larbuisson, Robert ^a   Lamy, Maurice ^a,b  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Amylase; Bypass; Cardiac surgery; Myeloperoxidase; Pancreas; Trypsin

Indexed keywords

ALPHA 1 ANTITRYPSIN; ALPHA 2 MACROGLOBULIN; AMYLASE; CALCIUM; ISOAMYLASE; MYELOPEROXIDASE; TRIACYLGLYCEROL LIPASE; TRYPSIN;

ADULT; AGED; ARTICLE; CARDIOPULMONARY BYPASS; CELL DAMAGE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HEART SURGERY; HUMAN; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; MULTIPLE REGRESSION; PANCREAS INJURY; PROSPECTIVE STUDY; RISK FACTOR;

AGED; ALPHA-MACROGLOBULINS; AMYLASES; CALCIUM; CARDIOPULMONARY BYPASS; FEMALE; HUMANS; ISOAMYLASE; LIPASE; MALE; MIDDLE AGED; PANCREAS; PANCREATIC DISEASES; PEROXIDASE; POSTOPERATIVE COMPLICATIONS; PROTEASE INHIBITORS; REGRESSION ANALYSIS; RISK FACTORS; TIME FACTORS; TRYPSIN;

EID: 34247202152     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/shk.0b013e31802b65f8     Document Type: Article

References (63)

1. Perryman RG, Hoerr S: Observations on postoperative pancreatitis and postoperative elevation of the serum amylase. Am J Surg 88:417-423, 1954.
2. Manhaffey JH, Howard JM: The incidence of postoperative pancreatitis: study of 131 surgical patients utilizing serum amylase concentration. Arch Surg 70: 348-352, 1955.
3. Tilney NL, Bailey GL, Morgan AP: Sequential system failure after rupture of abdominal aortic aneurysms. Ann Surg 178:117-122, 1973.
4. Warshaw AL, O'Hara PJ: Susceptibility of the pancreas to ischemic injury in shock. Ann Surg 188:197-201, 1978.
5. Jones MS, Dawson H: Studies of the ischemic pancreas in shock. Adv Shock Res 1:197-207, 1979.
6. Gmaz-Nikulin E, Nikulin A, Plamenac P, Hegewald G, Gaon D: Pancreatic lesions in shock and their significance. J Pathol 135:223-236, 1981.
7. Deby-Dupont G, Haas M, Pincemail J, Braun M, Lamy M, Deby C, Franchimont P: Immunoreactive trypsin in adult respiratory distress syndrome. 10:7-12, 1984.
8. Nicod L, Leuenberger C, Seydoux C, Rey F, Van Melle G, Perret C: Evidence for pancreatic injury in adult respiratory distress syndrome. Am Rev Respir Dis 131:696-699, 1985.
9. Weaver DW, Busuito MJ, Bouwman DL, Wilson RF: Interpretation of serumamylase levels in critically ill patients. Crit Care Med 13:532-533, 1985.
10. Feiner H: Pancreatitis after cardiac surgery. Am J Surg 684:131-135, 1976.
11. Haas GS, Warshaw AL, Daggett WM, Aretz HT: Acute pancreatitis after cardiopulmonary bypass. Am J Surg 149:508-515, 1985.
12. Forsyth RP, Hoffbrand BI, Melmon KL: Redistribution of cardiac output during hemorrhage in the unanesthetized monkey. Circ Res 27:311-320, 1970.
13. Göber I: Die Auswirkung des hypovolämischen Shocks auf das Pankreas. Wien Klin Wochenschr 87:2-11, 1975.
14. Ferguson JL, Merrill GF, Miller HI, Spitzer JJ: Regional blood flow redistribution during early burn shock in the guinea pig. Circ Shock 4: 317-326, 1977.
15. Florholmen J, Riepl R, Almdahl SM, Myklebust R, Burhol PG, Giercksky KE, Malm D: Impact of experimental endogenous gram-negative peritonitis on the pancreas of the rat as evaluated by cationic trypsin-like immunoreactivity in peritoneal fluid and serum and by electron microscopy of pancreatic tissue. Scand J Gastroenterol 22:313-320, 1987.
16. Hegewald G, Nikulin A, Gmaz-Nikulin E, Plamenac P, Barenwald G: Ultrastructural changes of the human pancreas in acute shock. Pathol Res Pract 179:610-615, 1985.
17. Endrich B, Klar E, Hammersen F: The microcirculation of the pancreas: state of the art. In: Messmer K, Hammersen F (eds.): Gastrointestinal Microcirculation. Progress in Applied Microcirculation, Vol 17. Basel, Switzerland: Karger AG, pp 144-174, 1990.
18. Gessler P, Pretre R, Hohl V, Rousson V, Fischer J, Dahinden C: CXC-chemokine stimulation of neutrophils correlates with plasma levels of myeloperoxidase and lactoferrin and contributes to clinical outcome after pediatric cardiac surgery. Shock 22:513-520, 2004.
19. Faymonville ME, Pincemail J, Duchateau J, Paulus JM, Adam A, Deby-Dupont G, Deby C, Albert A, Larbuisson R, Limet R, et al.: Myeloperoxidase and elastase as markers of leukocyte activation during cardiopulmonary bypass in humans. J Thorac Cardiovasc Surg 102:309-317, 1991.
20. Hashimoto K, Miyamoto H, Suzuki K, Horikoshi S, Matsui M, Arai T, Kurosawa H: Evidence of organ damage after cardiopulmonary bypass. J Thorac Cardiovasc Surg 104:666-673, 1992.
21. Farah B, Vuillemenot A, Lecompte T, Bara L, Pasquier C, Jebara V, Carpentier A, Fabiani JN: Myocardial neutrophil sequestration and activation related to the reperfusion of human heart during coronary artery surgery. Cardiovasc Res 28:1226-1230, 1994.
22. Kong C-W, Huang C-H, Hsu T-G, Tsai KK, Hsu C-F, huang M-C, Chen L-C: Leukocyte mitochondrial alterations after cardiac surgery involving cardiopulmonary bypass: clinical correlations. Shock 21:315-319, 2004.
23. Halter J, Steinberg J, Fink G, Lutz C, PCIone A, Maybury R, Fedors N, DiRocco J, Lee HM, Nieman G: Evidence of systemic cytokine release in patients undergoing cardiopulmonary bypass. J Extra Corpor Technol 37:272-277, 2005.
24. Raja SG, Dreyfus GD: Modulation of systemic inflammatory response after cardiac surgery. Asian Cardiovasc Thorac Ann 13:382-395, 2005.
25. Granger J, Remick D: Acute pancreatitis: models, markers, and mediators. Shock 24(suppl 1):45-51, 2005.
26. Morrissey R, Berk JE, Fridhandler L, Pelot D: The nature and significance of hyperamylasemia following operation. Ann Surg 178:67-71, 1974.
27. Paajanen H, Nuutinen P, Harmoinen A, Pöyhönen M, PitKänen O, Nordback I, Grönroos J, Nevalainen TJ: Hyperamylasemia after cardiopulmonary bypass: pancreatic cellular injury or impaired renal excretion of amylase? Surgery 123:504-510, 1998.
28. Fernandez-Del Castillo C, Harringer W, Warshaw AL, Vlahakes GJ, Koski G, Zaslavsky AM, Rattner DW: Risk factors for pancreatic cellular injury after cardiopulmonary bypass. N Engl J Med 325:382-387, 1991.
29. Caimi G, Hoffmann E, Montana M, Incalcaterre E, Dispensa F, D'Amico T, Canino B, Lo Presti R: Plasma markers of platelet and polymorphonuclear leukocyte activation in young adults with myocardial infarction. Clin Hemorheol Microcirc 32:67-74, 2005.
30. Gash O, Nys M, Deby-Dupont G, Chapelle J-P, Lamy M, Piérard LA, Legrand V. Acute neutrophil activation in direct stenting: comparison of stable and unstable angina patients. Int J Cardiol 112:59-65, 2005.
31. Lorentz K: α-Amylase assay: current state and future development. J Clin Chem Clin Biochem 17:499-504, 1979.
32. Warshaw AL, Lee KH: Characteristic alterations of serum isoenzymes of amylase in diseases of liver, pancreas, salivary gland, lung, and genitalia. J Surg Res 22:362-369, 1977.
33. Ziegenhorn J, Neumann U, Knitsch KW, Zwez W: Determination of serum lipase. Clin Chem 25:1067, 1979.
34. Malvano R, Marchisio M, Massaglia A, Giacosa PA, Zannino M, Andriulli A, Burlina A: Radioimmunoassay of trypsin-like substance in human serum. Scand J Gastroenterol 15:2-10, 1980.
35. Thomas L: Calcium (Ca)., In: Thomas L (ed.): Clinical Laboratory Diagnostics: Use and Assessment of Clinical Laboratory Results, 3rd ed. Frankfurt, Germany: TH-Books, pp 213-237, 1998.
36. Pincemail J, Deby-Dupont G, Deby C, Thirion A, Torpier G, Faymonville ME, Tomassini M, Lamy M, Franchimont P: Fast double antibody radioimmunoassay of human granulocyte myeloperoxidase and its application to human plasma. J Immunol Methods 137:181-191, 1991.
37. Albert A, Harris EK: Multivariate Interpretation of Clinical Laboratory Data. Statistics: Textbooks and Monographs, Vol. 75. New York: Marcel Dekker, 1987. 328 pp.
38. Panebianco AC, Scott SM, Dart CH, Takaro T, Echegaray HM: Acute pancreatitis following extracorporeal circulation. Ann Thorac Surg 9:562-567, 1970.
39. Svensson LG, Decker GD, Kinsley RB: A prospective study of hyperamylasemia and pancreatitis after cardiopulmonary bypass. Ann Thorac Surg 39:409-411, 1985.
40. Kazmierczak SC, Van Lente F: Incidence and source of hyperamylasemia after cardiac surgery. Clin Chem 34:916-919, 1988.
41. Rattner DW, Gu ZY, Vlahakes GJ, Warshaw A: Hyperamylasemia after cardiac surgery. Ann Surg 209:279-283, 1989.
42. Yadav D, Agarwal N, Pitchumoni CS: A critical evaluation of laboratory tests in acute pancreatitis. Am J Gastroenterol 97:1309-1318, 2002.
43. Kylänpää-Bäck M-L, Kemppainen E, Puolakkainen P: Trysin-based laboratory methods and carboxypeptidase activation peptide in acute pancreatitis. JOP 3:34-48, 2002.
44. Borgström A, Ohlsson K: Studies on the turnover of endogenous cathodal trypsinogen in man. Eur J Clin Invest 8:379-382, 1978.
45. 2- macroglobulin complexes by macrophages. Biochem Biophys Acta 411:295-304, 1975.
46. Frick TW, Fernandez-del Castillo C, Bimmler D, Warshaw AL: Elevated calcium and activation of trypsinogen in rat pancreatic acini. Gut 41:339-343, 1997.
47. Raraty M, Ward J, Erdemli G, Vaillant C, Neoptolemos JP, Sutton R, Petersen OH: Calcium-dependent enzyme activation and vacuole formation in the aPCIal granular region of pancreatic acinar cells. Proc Natl Acad Sci U S A 97:13126-13131, 2000.
48. Hlouschek V, Finkes T, Turi S, Weber IA, Singh J, Domschke W, Schnekenburger J, Kruger B, Lerch MM: Early changes in pancreatic acinar cell calcium signaling after pancreatic duct obstruction. J Biol Chem 278:9361-9369, 2003.
49. Mithofer K, Warshaw AL, Frick TW, Lewandroski KB, Koski G, Rattner DW, Fernandez-Del Castillo C: Calcium administration augments pancreatic injury and ectoPCI trypsinogen activation after temporary systemic hypotension in rats. Anesthesiology 83:1266-1273, 1995.
50. Zhou ZG, Chen YQ, Liu XB, Hu WM, Tian BL, Chen HQ: Changes of cytosolic [Ca2+] i in neutrophils in pancreatic microcirculation of rats with caerulein-induced acute pancreatitis under fluid shear stress. World J Gastroenterol 10:3185-3187, 2004.
51. Biglioli P, Cannata A, Alamanni F, Naliato M, Porqueddu M, Zanobini M, Tremoli E, Parolari A: Biological effects of off-pump vs. on-pump coronary artery surgery: focus on inflammation, hemostasis and oxidative stress. Eur J Cardiothorac Surg 24:260-269, 2003.
52. Chello M, Mastroroberto P, Quirino A, Cuda G, Perticone F, Cirillo F, Covino E: Inhibition of neutrophil apoptosis after coronary bypass operation with cardiopulmonary bypass. Ann Thorac Surg 73:123-130, 2002.
53. Kumle B, Boldt J, Suttner SW, Piper SN, Lehmann A, Blome M: Influence of prolonged cardiopulmonary bypass times on splanchnic perfusion and markers of splanchnic organ function. Ann Thorac Surg 75:1558-1564, 2003.
54. Thorén A, Jakob SM, Pradl R, Elam M, Ricksten SE, Takala J: Jejunal and gastric mucosal perfusion versus splanchnic blood flow and metabolism: an observational study on postcardiac surgical patients. Crit Care Med 28:3649-3654, 2000.
55. Andrasi TB, Bielik H, Blazovics A, Zima E, Vago H, Szabo G, Juhasz-Nagy A: Mesenteric vascular dysfunction after cardiopulmonary bypass with cardiac arrest is aggravated by coexistent heart failure. Shock 23:324-329, 2005.
56. Sakorafas GH, Tsiotos GG, Satt MG: Ischemia/Reperfusion-induced pancreatitis. Dig Surg 17:3-14, 2000.
57. Di Lisa F, Canton M, Menabo R, Dodoni G, Bernardi P: Mitochondria and reperfusion injury. The role of permeability transition. Basic Res Cardiol 98:235-241, 2003.
58. De Coninck B, Meert P, Hanique G, Jadoul M, Dugernier T, el Gariani A, Marion E, Ferrant A, Reynaert M: Scintigraphy with Indium-labelled leukocytes in acute pancreatitis. Acta Gastroenterol Belg 54:176-173, 1991.
59. Hartwig W, Carter EA, Jimenez RE, Werner J, Fischman AJ, Fernandez-Del Castillo C, Warshaw AL: Chemotactic peptide uptake in acute pancreatitis: correlation with tissue accumulation of leucocytes. J Appl Physiol 87:743-749, 1999.
60. Appelros S, Petersson U, Toh S, Johnson C, Borgstrom A: Activation peptide of carboxypeptidase B and anionic trypsinogen as early predictors of the severity of acute pancreatitis. Br J Surg 88:216-221, 2001.
61. Deitch EA, Shi HP, Lu Q, Feketeova E, Xu DZ: Serine proteases are involved in the pathogenesis of trauma-hemorrhagic shock-induced gut and lung injury. Shock 19:452-456, 2003.
62. Waldo SW, Rosario HS, Penn AH, Schmid-Schonbein GW: Pancreatic digestive enzymes are potent generators of mediators for leukocyte activation and mortality. Shock 20:138-143, 2003.
63. Acosta JA, Hoyt DB, Schmid-Schonbein GW, Hugli TE, Anjaria DJ, Frankel DA, Coimbra R: Intraluminal pancreatic serine protease activity, mucosal permeability, and shock: a review. Shock 26:3-9, 2006.