Chemotactic peptide uptake in acute pancreatitis: Correlation with tissue accumulation of leukocytes

Journal of Applied Physiology

Volumn 87, Issue 2, 1999, Pages 743-749

  Hartwig, Werner ^a   Carter, Edward A ^a   Jimenez, Ramon E ^a   Werner, Jens ^a   Fischman, Alan J ^a   Fernandez Del Castillo, Carlos ^a   Warshaw, Andrew L ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Chemotactic factors; Inflammation; Leukocytes; N formyl methionyl leucyl phenylalanine

Indexed keywords

FORMYLMETHIONYLLEUCYLPHENYLALANINE; MYELOPEROXIDASE; PEPTIDE; TECHNETIUM 99M;

ACUTE PANCREATITIS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; INFLAMMATION; LEUKOCYTE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0032865436     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1999.87.2.743     Document Type: Article

References (26)

1. Abrams, M. J., M. Juweid, C. I. ten Kate, D. A. Schwartz, M. M. Hauser, F. E. Gaul, A. J. Fuccello, R. H. Rubin, H. W. Strauss, and A. J. Fischman. Technetium-99m-human polyclonal IgG radiolabeled via the hydrazino nicotinamide derivative for imaging focal sites of infection in rats. J. Nucl. Med. 31: 2022-2028, 1990.
2. Babich, J. W., H. Solomon, M. C. Pike, D. Kroon, W. Graham, M. J. Abrams, R. G. Tompkins, R. H. Rubin, and A. J. Fischman. Technetium-99m-labeled hydrazino nicotinamide derivatized chemotactic peptide analogs for imaging focal sites of bacterial infection. J. Nucl. Med. 34: 1964-1974, 1993.
3. Babich, J. W., R. G. Tompkins, W. Graham, S. A. Barrow, and A. J. Fischman. Localization of radiolabeled chemotactic peptide at focal sites of Escherichia coli infection in rabbits: evidence for a receptor-specific mechanism. J. Nucl. Med. 38: 1316-1322, 1997.
4. Corstens, F. H., and J. W. van der Meer. Chemotactic peptides: new locomotion for imaging of infection? J. Nucl. Med. 32: 491-494, 1991.
5. Fernandez-del Castillo, C., J. Schmidt, A. L. Warshaw, and D. W. Rattner. Interstitial protease activation is the central event in progression to necrotizing pancreatitis. Surgery 116: 497-504, 1994.
6. 99mTc-labeled chemotactic peptide. J. Trauma 38: 223-227, 1995.
7. Fischman, A. J., M. C. Pike, D. Kroon, A. J. Fucello, D. Rexinger, C. ten Kate, R. Wilkinson, R. H. Rubin, and H. W. Strauss. Imaging focal sites of bacterial infection in rats with indium-111-labeled chemotactic peptide analogs. J. Nucl. Med. 32: 483-491, 1991.
8. Fischman, A. J., D. Rauh, H. Solomon, J. W. Babich, R. G. Tompkins, D. Kroon, H. W. Strauss, and R. H. Rubin. In vivo bioactivity and biodistribution of chemotactic peptide analogs in nonhuman primates. J. Nucl. Med. 34: 2130-2134, 1993.
9. Guice, K. S., K. T. Oldham, K. J. Johnson, R. G. Kunkel, M. L. Morganroth, and P.A. Ward. Pancreatitis-induced acute lung injury. An ARDS model. Ann. Surg. 208: 71-77, 1988.
10. Hartwig, W., J. Werner, R. E. Jimenez, K. Lewandrowski, J. Weimann, A. L. Warshaw, and C. Fernandez-del Castillo. Activation of circulating trypsinogen contributes to pancreatitis-associated lung injury (PALI) (Abstract). Pancreas 17: 439, 1998.
11. Hurley, P. R., A. Cook, A. Jehanli, B. M. Austen, and J. Hermon-Taylor. Development of radioimmunoassays for free tetra-L-aspartyl-L-lysine trypsinogen activation peptides (TAP). J. Immunol. Methods 111: 195-203, 1988.
12. Klar, E., K. Messmer, A. L. Warshaw, and C. Herfarth. Pancreatic ischaemia in experimental acute pancreatitis: mechanism, significance and therapy. Br. J. Surg. 77: 1205-1210, 1990.
13. Klebanoff, S. J., A. M. Waltersdorph, and H. Rosen. Antimicrobial activity of myeloperoxidase. Methods Enzymol. 105: 399-403, 1984.
14. Knoefel, W. T., N. Kollias, A. L. Warshaw, H. Waldner, N. S. Nishioka, and D. W. Rattner. Pancreatic microcirculatory changes in experimental pancreatitis of graded severity in the rat. Surgery 116: 904-913, 1994.
15. Lampel, M., and H. F. Kern. Acute interstitial pancreatitis in the rat induced by excessive doses of a pancreatic secretagogue. Virchows Arch. 373: 97-117, 1977.
16. Merrifield, R. B. Solid-phase peptide synthesis. Adv. Enzymol. Relat. Areas Mol. Biol. 32: 221-296, 1969.
17. Oyen, W. J., O. C. Boerman, C. J. van der Laken, R. A. Claessens, J. W. van der Meer, and F. H. Corstens. The uptake mechanisms of inflammation- and infection-localizing agents. Eur. J. Nucl. Med. 23: 459-465, 1996.
18. 111In-labeled nonspecific immunoglobulin scanning in the detection of focal infection. N. Engl J. Med. 321: 935-940, 1989.
19. Saluja, A., I. Saito, M. Saluja, M. J. Houlihan, R. E. Powers, J. Meldolesi, and M. Steer. In vivo rat pancreatic acinar cell function during supramaximal stimulation with caerulein. Am. J. Physiol. 249 (Gastrointest. Liver Physiol. 12): G702-G710, 1985.
20. 111In-labelled granulocytes. Relationship to labelling techniques. Scand. J. Haematol. 30: 151-160, 1983.
21. Schiffmann, E., B. A. Corcoran, and S. M. Wahl. N-formylmethionyl peptides as chemoattractants for leucocytes. Proc. Natl. Acad. Sci. USA 72: 1059-1062, 1975.
22. Schmidt, J., C. Fernandez-del Castillo, D. W. Rattner, K. Lewandrowski, C. C. Compton, and A. L. Warshaw. Trypsinogen-activation peptides in experimental rat pancreatitis: prognostic implications and histopathologic correlates. Gastroenterology 103: 1009-1016, 1992.
23. Schmidt, J., D. W. Rattner, K. Lewandrowski, C. C. Compton, U. Mandavilli, W. T. Knoefel, and A. L. Warshaw. A better model of acute pancreatitis for evaluating therapy. Ann. Surg. 215: 44-56, 1992.
24. Van der Laken, C. J., O. C. Boerman, W. J. Oyen, M. T. van de Ven, D. S. Edwards, J. A. Barrett, J. W. van der Meer, and F. H. Corstens. Technetium-99m-labeled chemotactic peptides in acute infection and sterile inflammation. J. Nucl. Med. 38: 1310-1315, 1997.
25. Werner, J., S. C. Dragotakes, C. Fernandez-del Castillo, J. A. Rivera, J. Ou, D. W. Rattner, A. J. Fischman, and A. L. Warshaw. Technetium-99m-labeled white blood cells: a new method to define the local and systemic role of leukocytes in acute experimental pancreatitis. Ann. Surg. 227: 86-94, 1998.
26. Williams, L. T., R. Snyderman, M. C. Pike, and R. J. Lefkowitz. Specific receptor sites for chemotactic peptides on human polymorphonuclear leukocytes. Proc. Soc. Exp. Biol. Med. 74: 1204-1208, 1977.