Systemic infections cause exaggerated local inflammation in atherosclerotic coronary arteries: Clues to the triggering effect of acute infections on acute coronary syndromes

Texas Heart Institute Journal

Volumn 34, Issue 1, 2007, Pages 11-18

  Madjid, Mohammad ^a,b,d   Vela, Deborah ^b   Khalili Tabrizi, Hessam ^b   Casscells, S Ward ^a,b   Litovsky, Silvio ^a,c  

^a ST LUKE S EPISCOPAL HOSPITAL   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c University of Alabama at Birmingham   (United States)

^d TEXAS HEART INSTITUTE   (United States)

Author keywords

Arteriosclerosis complications; Cardiovascular diseases diagnosis prevention control; Coronary arteriosclerosis pathology; Coronary disease pathology; Coronary vessels pathology; Inflammation complications etiology pathology

Indexed keywords

EOSIN; HEMATOXYLIN; MARKER;

ADULT; AGED; ARTICLE; ATHEROSCLEROSIS; AUTOPSY; CELL DENSITY; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY OBSTRUCTION; DENDRITIC CELL; DISEASE EXACERBATION; FEMALE; HEART INFARCTION; HUMAN; HUMAN TISSUE; INFECTION; MACROPHAGE; MALE; MYOCARDITIS; PHYSICAL EXAMINATION; STAINING; T LYMPHOCYTE; THROMBOSIS;

ACUTE DISEASE; AGED; ANTIGENS, CD; ANTIGENS, CD3; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; CASE-CONTROL STUDIES; CONNECTIVE TISSUE; CORONARY ARTERIOSCLEROSIS; CORONARY STENOSIS; CORONARY THROMBOSIS; DENDRITIC CELLS; FEMALE; HUMANS; MACROPHAGES; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; RESEARCH DESIGN; RESPIRATORY TRACT INFECTIONS; S100 PROTEINS; SEPSIS; SYNDROME; T-LYMPHOCYTES; TUNICA INTIMA; TUNICA MEDIA; URINARY TRACT INFECTIONS;

EID: 34247164469     PISSN: 07302347     EISSN: 15266702     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med 1999;340:115-26.
2. Virmani R, Kolodgie FD, Burke AP, Farb A, Schwartz SM. Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol 2000;20:1262-75.
3. Libby P, Egan D, Skarlatos S. Roles of infectious agents in atherosclerosis and restenosis: an assessment of the evidence and need for future research. Circulation 1997;96:4095-103.
4. Epstein SE, Zhou YF, Zhu J. Infection and atherosclerosis: emerging mechanistic paradigms. Circulation 1999;100:e20-8.
5. Madjid M, Aboshady I, Awan I, Litovsky S, Casscells SW. Influenza and cardiovascular disease: is there a causal relationship? Tex Heart Inst J 2004;31:4-13.
6. Madjid M, Naghavi M, Litovsky S, Casscells SW. Influenza and cardiovascular disease: a new opportunity for prevention and the need for further studies. Circulation 2003;108:2730-6.
7. Pesonen E, Siitonen O. Acute myocardial infarction precipitated by infectious disease. Am Heart J 1981;101:512-3.
8. Abinader EG, Sharif DS, Omary M. Inferior wall myocardial infarction preceded by acute exudative pharyngitis in young males. Isr J Med Sci 1993;29:764-9.
9. Bourne G, Wedgwood J. Heart-disease and influenza. Lancet 1959;1:1226-8.
10. Penttinen J, Valonen P. The risk of myocardial infarction among Finnish farmers seeking medical care for an infection. Am J Public Health 1996;86:1440-2.
11. Zheng ZJ, Mittleman MA, Tofler GH, Pomeroy C, Dampier C, Wides B, Muller JE. Infections prior to acute myocardial infarction onset [abstract]. J Am Coll Cardiol 1998;31(Suppl A):132A.
12. Meier CR, Jick SS, Derby LE, Vasilakis C, Jick H. Acute respiratory-tract infections and risk of first-time acute myocardial infarction. Lancet 1998;351:1467-71.
13. Spencer FA, Goldberg RJ, Becker RC, Gore JM. Seasonal distribution of acute myocardial infarction in the second National Registry of Myocardial Infarction. J Am Coll Cardiol 1998;31:1226-33.
14. Sheth T, Nair C, Muller J, Yusuf S. Increased winter mortality from acute myocardial infarction and stroke: the effect of age. J Am Coll Cardiol 1999;33:1916-9.
15. Jakovljevic D, Salomaa V, Sivenius J, Tamminen M, Sarti C, Salmi K, et al. Seasonal variation in the occurrence of stroke in a Finnish adult population. The FINMONICA Stroke Register. Finnish Monitoring Trends and Determinants in Cardiovascular Disease. Stroke 1996;27:1774-9.
16. Collins SD. Excess mortality from causes other than influenza and pneumonia during influenza epidemics. Pub Health Rep 1932;47:2159-79.
17. Naghavi M, Barlas Z, Siadaty S, Naguib S, Madjid M, Casscells W. Association of influenza vaccination and reduced risk of recurrent myocardial infarction. Circulation 2000; 102:3039-45.
18. Gurfinkel EP, de la Fuente RL, Mendiz O, Mautner B. Influenza vaccine pilot study in acute coronary syndromes and planned percutaneous coronary interventions: the FLU Vaccination Acute Coronary Syndromes (FLUVACS) Study. Circulation 2002;105:2143-7.
19. Lavallee P, Perchaud V, Gautier-Bertrand M, Grabli D, Amarenco P. Association between influenza vaccination and reduced risk of brain infarction [published erratum appears in Stroke 2002;33:1171]. Stroke 2002;33:513-8.
20. Nichol KL, Nordin J, Mullooly J, Lask R, Fillbrandt K, Iwane M. Influenza vaccination and reduction in hospitalizations for cardiac disease and stroke among the elderly. N Engl J Med 2003;348:1322-32.
21. Siscovick DS, Raghunathan TE, Lin D, Weinmann S, Arbogast P, Lemaitre RN, et al. Influenza vaccination and the risk of primary cardiac arrest. Am J Epidemiol 2000;152:674-7.
22. Peiris JS, Chu CM, Cheng VC, Chan KS, Hung IF, Poon LL, et al. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet 2003;361:1767-72.
23. Kol A, Libby P. Molecular mediators of arterial inflammation: a role for microbial products? Am Heart J 1999;138(5 Pt 2):S450-2.
24. Naghavi M, Wyde P, Litovsky S, Madjid M, Akhtar A, Naguib S, et al. Influenza infection exerts prominent inflammatory and thrombotic effects on the atherosclerotic plaques of apolipoprotein E-deficient mice. Circulation 2003;107:762-8.
25. Li L, Messas E, Batista EL Jr, Levine RA, Amar S. Porphyromonas gingivalis infection accelerates the progression of atherosclerosis in a heterozygous apolipoprotein E-deficient murine model [published erratum appears in Circulation 2002;105:1617]. Circulation 2002;105:861-7.
26. Van Lenten BJ, Wagner AC, Anantharamaiah GM, Garber DW, Fishbein MC, Adhikary L, et al. Influenza infection promotes macrophage traffic into arteries of mice that is prevented by D-4F, an apolipoprotein A-I mimetic peptide. Circulation 2002;106:1127-32.
27. Van Lenten BJ, Wagner AC, Nayak DP, Hama S, Navab M, Fogelman AM. High-density lipoprotein loses its anti-inflammatory properties during acute influenza A infection. Circulation 2001;103:2283-8.
28. Vela D, Buja LM, Madjid M, Burke A, Naghavi M, Willerson JT, et al. The role of periadventitial fat in atherosclerosis: an adipose subset with potential diagnostic and therapeutic implications. Arch Pathol Lab Med. In press.
29. Okamoto E, Couse T, De Leon H, Vinten-Johansen J, Goodman RB, Scott NA, Wilcox JN. Perivascular inflammation after balloon angioplasty of porcine coronary arteries. Circulation 2001;104:2228-35.
30. Hansson GK. Regulation of immune mechanisms in atherosclerosis. Ann N Y Acad Sci 2001;947:157-66.
31. Wick G, Knoflach M, Xu Q. Autoimmune and inflammatory mechanisms in atherosclerosis. Annu Rev Immunol 2004; 22:361-403.
32. Houtkamp MA, de Boer OJ, van der Loos CM, van der Wal AC, Becker AE. Adventitial infiltrates associated with advanced atherosclerotic plaques: structural organization suggests generation of local humoral immune responses. J Pathol 2001;193:263-9.
33. Bobryshev YV, Lord RS, Parsson H. Immunophenotypic analysis of the aortic aneurysm wall suggests that vascular dendritic cells are involved in immune responses. Cardiovasc Surg 1998;6:240-9.
34. Hackam DG, Mamdani M, Li P, Redelmeier DA. Statins and sepsis in patients with cardiovascular disease: a population-based cohort analysis. Lancet 2006;367:413-8.
35. Merx MW, Weber C. Statins: a preventive strike against sepsis in patients with cardiovascular disease? Lancet 2006;367: 372-3.
36. Madjid M, Casscells SW. Of birds and men: cardiologists' role in influenza pandemics. Lancet 2004;364:1309.
37. Madjid M, Miller C, Zarubaev VV, Marinich IG, Kiselev OI, Lobzin YV, et al. Influenza epidemics are associated with a surge in autopsy-confirmed coronary artery disease death: results from eight years of autopsies in 34,892 subjects. Eur Heart J. In press.
38. Buja LM, Willerson JT. Role of inflammation in coronary plaque disruption. Circulation 1994;89:503-5.
39. Sharma S, Kumar A. Septic shock, multiple organ failure, and acute respiratory distress syndrome. Curr Opin Pulm Med 2003;9:199-209.
40. Almog Y, Shefer A, Novack V, Maimon N, Barski L, Eizinger M, et al. Prior statin therapy is associated with a decreased rate of severe sepsis. Circulation 2004;110:880-5.
41. Rutger Persson G, Ohlsson O, Pettersson T, Renvert S. Chronic periodontitis, a significant relationship with acute myocardial infarction. Eur Heart J 2003;24:2108-15.