From preconditioning to postconditioning: Novel interventions in the armory of salvage of the ischemic heart

Hellenic Journal of Cardiology

Volumn 47, Issue 6, 2006, Pages 321-323

  Iliodromitis, Efstathios K ^a,b   Kremastinos, Dimitrios T ^a  

^a IASO GENERAL HOSPITAL   (Greece)

^b NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

Author keywords

Infarction; Myocardial ischemia; Postconditioning; Preconditioning

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE;

EDITORIAL; HEART ARRHYTHMIA; HEART INFARCTION; HEART MUSCLE NECROSIS; HUMAN; ISCHEMIC HEART DISEASE; NONHUMAN; REPERFUSION; ST SEGMENT ELEVATION; THORAX PAIN; ANIMAL; HEART INFARCTION PREVENTION; METHODOLOGY; REPERFUSION INJURY;

ANIMALS; HUMANS; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MYOCARDIAL REPERFUSION INJURY;

EID: 34247146012     PISSN: 10117970     EISSN: 10117970     Source Type: Journal    
DOI: None     Document Type: Editorial

References (23)

1. Murry CE, Jennings RB, Reimer KA: Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 1986; 74: 1124-1136.
2. Przyklenk K, Kloner R: Ischemic preconditioning: exploring the paradox. Prog Cardiovas Dis 1998; 40: 517-547.
3. Kyriakides ZS, Psychari S, Iliodromitis EK, et al: Hyperlipidemia prevents the expected reduction of myocardial ischemia on repeated balloon inflations during angioplasty. Chest 2002; 121: 1211-1215.
4. Yellon DM, Downey JM: Preconditioning the myocardium: from cellular physiology to clinical cardiology. Physiol Rev 2003: 83: 1113-1151.
5. Zhao ZQ, Corvera JS, Halkos ME, et al: Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning. Am J Physiol 2003; 285: H579-H588.
6. Kloner RA, Jennings RB: Consequences of brief ischemia: Stunning, preconditioning and their clinical implications (Part I). Circulation 2001; 104: 2981-2989.
7. Przyklenk K, Kloner RA: Calcium antagonists and the stunned myocardium. J Cardiovasc Pharmacol 1991; 18 (Suppl 10): S93-S101.
8. Vinten-Johansen J, Yellon DM, Opie LH: Postconditioning: a simple, clinically applicable procedure to improve revascularization in acute myocardial infarction. Circulation 2005; 112: 2085-2088.
9. Paraskevaidis IA, Iliodromitis EK, Kremastinos DT, et al: Deferoxamine infusion during coronary artery bypass grafting ameliorates lipid peroxidation and protects myocardium against reperfusion injury: immediate and long term results. Eur Heart J 2005; 26: 263-270.
10. Argaud L, Gateau-Roesch O, Raisky O, et al: Postconditioning inhibits mitochondrial permability transition. Circulation 2005; 111: 194-197.
11. Tsang A, Hausenloy DJ, Mocanu MM, et al: Postconditioning: a form of "modified reperfusion" protects the myocardium by activating the phosphatidylinositol 3-kinase-Akt pathway. Circ Res 2004; 95: 230-232.
12. Yang XM, Philipp S, Downey JM, et al: Postconditioning's protection is not dependent on circulating blood factors or cells but involves adenosine receptors and requires PI3-kinase and guanylyl cyclase activation. Basic Res Cardiol 2005: 100; 57-63.
13. Yang XM, Proctor JB, Cui L, et al: Multiple, brief coronary occlusions during early reperfusion protect rabbit hearts by targeting cell signalling pathways. J Am Coll Cardiol 2004; 44: 1103-1110.
14. Philipp S, Downey JM, Cohen M:. Postconditioning must be initiated in less than 1 minute following reperfusion and is dependent on adenosine receptors and PI3-kinase [Abstract]. Circulation 2004; 110(Suppl III): 111-168.
15. Staat P, Rioufol G, Piot C, et al: Postconditioning the human heart. Circulation 2005; 112: 2143-2148.
16. Loukogeorgakis SP, Panagiotidou AT, Yellon DM, et al: Postconditioning protects against endothelial ischemia-reperfusion injury in the human forearm. Circulation 2006; 113: 1015-1019.
17. Cohen MV, Yang X-M, Downey JM: Conscious rabbits become tolerant to multiple episodes of ischemic preconditioning. Circ Res 1994; 74: 998-1004.
18. Iliodromitis EK, Kremastinos DT, Katritsis DG, et al: Mutliple cycles of preconditioning cause loss of protection in open-chest rabbits. J Mol Cell Cardiol 1997; 29: 915-920.
19. Iliodromitis EK, Zoga A, Vrettou A, et al: The effectiveness of postconditioning and preconditioning on infarct size in hypercholesterolemic and normal anesthetized rabbits. Atherosclerosis 2006; 188: 356-362.
20. Schwartz LM, Lagranha CJ: Ischemic postconditioning during reperfusion activates Akt and ERK without protecting against lethal myocardial ischemia-reperfusion injury in pigs. Am J Physiol Heart Circ Physiol 2006; 290: H1011-H1018.
21. Iliodromitis EK, Georgiadis M, Cohen MV, et al: Protection from postconditioning depends on the number of short ischemic insults in anesthetized pigs. Basic Res Cardiol 2006; 101: 502-507.
22. Iliodromitis EK, Papadopoulos CC, Markianos M, et al: Alterations in circulating c-GMP during short and long ischemia in preconditioning. Basic Res Cardiol 1996; 91: 234-239.
23. Heusch G: Postconditioning. Old wine in a new bottle? J Am Coll Cardiol 2004; 44: 1111-1112.