Effects of chronic opioid exposure on guinea pig mu opioid receptor in Chinese hamster ovary cells: Comparison with human and rat receptor

Biochemical Pharmacology

Volumn 73, Issue 11, 2007, Pages 1818-1828

  Wallisch, Michael ^a   Nelson, Cole S ^a   Mulvaney, Julia M ^a   Hernandez, Heather S ^a   Smith, Sue Ann ^b   Olsen, George D ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Desensitization; Down regulation; G protein coupled receptor; GTP S binding; Methadone; Morphine

Indexed keywords

ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); METHADONE; MORPHINE; MU OPIATE RECEPTOR; OPIATE;

AGONIST; ANIMAL CELL; ARTICLE; CHO CELL; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DESENSITIZATION; DRUG EFFICACY; DRUG EXPOSURE; DRUG POTENCY; DRUG RECEPTOR BINDING; GUINEA PIG; HUMAN; HUMAN VERSUS ANIMAL COMPARISON; LIGAND BINDING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; RECEPTOR INTRINSIC ACTIVITY; SPECIES DIFFERENCE;

ANALGESICS, OPIOID; ANIMALS; BINDING, COMPETITIVE; CHO CELLS; CRICETINAE; CRICETULUS; FEMALE; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); GUINEA PIGS; HUMANS; MORPHINE; RATS; RECEPTORS, OPIOID, MU; SPECIES SPECIFICITY; TRANSFECTION;

EID: 34247144649     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.02.001     Document Type: Article

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