Positron Emission Tomography-Guided, Focal-Dose Escalation Using Intensity-Modulated Radiotherapy for Head and Neck Cancer

International Journal of Radiation Oncology Biology Physics

Volumn 68, Issue 1, 2007, Pages 126-135

  Madani, Indira ^a   Duthoy, Wim ^a   Derie, Cristina ^a   De Gersem, Werner ^a   Boterberg, Tom ^a   Saerens, Micky ^a   Jacobs, Filip ^a   Grégoire, Vincent ^b   Lonneux, Max ^b   Vakaet, Luc ^a   Vanderstraeten, Barbara ^a,c   Bauters, Wouter ^a   Bonte, Katrien ^a   Thierens, Hubert ^c   De Neve, Wilfried ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^c GHENT UNIVERSITY   (Belgium)

Author keywords

18F FDG PET; Focal dose escalation; Head and neck cancer; Intensity modulated radiotherapy

Indexed keywords

DOSIMETRY; GLUCOSE; POSITRON EMISSION TOMOGRAPHY; RADIOTHERAPY; TOXICITY; TUMORS;

FOCAL-DOSE ESCALATION; HEAD AND NECK CANCER; INTENSITY-MODULATED RADIOTHERAPY;

ONCOLOGY;

CISPLATIN; FLUORODEOXYGLUCOSE F 18;

ADULT; ARTICLE; CANCER GROWTH; CANCER SURVIVAL; CLINICAL ARTICLE; CLINICAL TRIAL; DIAGNOSTIC IMAGING; DYSPHAGIA; FEASIBILITY STUDY; FEMALE; FOLLOW UP; GASTROSTOMY; HEAD AND NECK CANCER; HUMAN; INTENSITY MODULATED RADIATION THERAPY; MALE; MAXIMUM TOLERATED DOSE; MORTALITY; MUCOSA INFLAMMATION; OUTCOME ASSESSMENT; PHASE 1 CLINICAL TRIAL; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIATION DOSE; RELAPSE; SIDE EFFECT; SKIN TOXICITY; STRIDOR; SURVIVAL RATE; TRACHEOTOMY; TREATMENT FAILURE; TREATMENT OUTCOME; TREATMENT RESPONSE; TUMOR VOLUME; WEIGHT REDUCTION;

ADULT; AGED; DISEASE-FREE SURVIVAL; FEASIBILITY STUDIES; FEMALE; FLUORODEOXYGLUCOSE F18; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MAXIMUM TOLERATED DOSE; MIDDLE AGED; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; RADIOTHERAPY DOSAGE; RADIOTHERAPY, INTENSITY-MODULATED; TREATMENT FAILURE;

EID: 34247126954     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2006.12.070     Document Type: Article

References (33)

1. Dawson L.A., Anzai Y., Marsh L., et al. Patterns of local-regional recurrence following parotid-sparing conformal and segmental intensity-modulated radiotherapy for head and neck cancer. Int J Radiat Oncol Biol Phys 46 (2000) 1117-1126
2. Chao K.S., Ozyigit G., Tran B.N., et al. Patterns of failure in patients receiving definitive and postoperative IMRT for head-and-neck cancer. Int J Radiat Oncol Biol Phys 55 (2003) 312-321
3. Eisbruch A., Marsh L.H., Dawson L.A., et al. Recurrences near base of skull after IMRT for head-and-neck cancer: implications for target delineation in high neck and for parotid gland sparing. Int J Radiat Oncol Biol Phys 59 (2004) 28-42
4. Lauve A., Morris M., Schmidt-Ullrich R., et al. Simultaneous integrated boost intensity-modulated radiotherapy for locally advanced head-and-neck squamous cell carcinomas: II-clinical results. Int J Radiat Oncol Biol Phys 60 (2004) 374-387
5. Clavo A.C., Brown R.S., and Wahl R.L. Fluorodeoxyglucose uptake in human cancer cell lines is increased by hypoxia. J Nucl Med 36 (1995) 1625-1632
6. Clavo A.C., and Wahl R.L. Effects of hypoxia on the uptake of tritiated thymidine, l-leucine, l-methionine, and FDG in cultured cancer cells. J Nucl Med 37 (1996) 502-506
7. Burgman P., Odonoghue J.A., Humm J.L., et al. Hypoxia-induced increase in FDG uptake in MCF7 cells. J Nucl Med 42 (2001) 170-175
8. Dearling J.L., Flynn A.A., Sutcliffe-Goulden J., et al. Analysis of the regional uptake of radiolabeled deoxyglucose analogs in human tumor xenografts. J Nucl Med 45 (2004) 101-107
9. Pugachev A., Ruan S., Carlin S., et al. Dependence of FDG uptake on tumor microenvironment. Int J Radiat Oncol Biol Phys 62 (2005) 545-553
10. Rajendran J.G., Mankoff D.A., O'Sullivan F., et al. Hypoxia and glucose metabolism in malignant tumors. Evaluation by [18F]fluoromisonidazole and [18F]fluorodeoxyglucose positron emission tomography imaging. Clin Cancer Res 10 (2004) 2245-2252
11. Minn H., Clavo A.C., and Wahl R.L. Influence of hypoxia on tracer accumulation in squamous-cell carcinoma: in vitro evaluation for PET imaging. Nucl Med Biol 23 (1996) 941-946
12. Zhao S., Kuge Y., Mochizuki T., et al. Biologic correlates of intratumoral heterogeneity in 18F-FDG distribution with regional expression of glucose transporters and hexokinase-II in experimental tumor. J Nucl Med 46 (2005) 675-682
13. Daisne J.F., Duprez T., Weynand B., et al. Tumor volume in pharyngolaryngeal squamous cell carcinoma: comparison at CT, MR imaging, and FDG PET and validation with surgical specimen. Radiology 233 (2004) 93-100
14. Nishioka T., Shiga T., Shirato H., et al. Image fusion between 18FDG-PET and MRI/CT for radiotherapy planning of oropharyngeal and nasopharyngeal carcinomas. Int J Radiat Oncol Biol Phys 53 (2002) 1051-1057
15. Paulino A.C., Koshy M., Howell R., et al. Comparison of CT- and FDG-PET-defined gross tumor volume in intensity-modulated radiotherapy for head-and-neck cancer. Int J Radiat Oncol Biol Phys 61 (2005) 1385-1392
16. Schwartz D.L., Ford E.C., Rajendran J., et al. FDG-PET/CT-guided intensity modulated head and neck radiotherapy: a pilot investigation. Head Neck 27 (2005) 478-487
17. Geets X., Daisne J.F., Tomsej M., et al. Impact of the type of imaging modality on target volumes delineation and dose distribution in pharyngo-laryngeal squamous cell carcinoma: comparison between pre- and per-treatment studies. Radiother Oncol 78 (2006) 291-297
18. Mohan R., Wu Q., Manning M., et al. Radiobiological considerations in the design of fractionation strategies for intensity-modulated radiation therapy of head and neck cancers. Int J Radiat Oncol Biol Phys 46 (2000) 619-630
19. Tate D.J., Adler J.R., Chang S.D., et al. Stereotactic radiosurgical boost following radiotherapy in primary nasopharyngeal carcinoma: impact on local control. Int J Radiat Oncol Biol Phys 45 (1999) 915-921
20. De Nittis A.S., Liu L., Rosenthal D.I., et al. Nasopharyngeal carcinoma treated with external radiotherapy, brachytherapy, and concurrent/adjuvant chemotherapy. Am J Clin Oncol 25 (2002) 93-95
21. Rudoltz M.S., Perkins R.S., Luthmann R.W., et al. High-dose-rate brachytherapy for primary carcinomas of the oral cavity and oropharynx. Laryngoscope 109 (1999) 1967-1973
22. Daisne J.F., Sibomana M., Bol A., et al. Tri-dimensional automatic segmentation of PET volumes based on measured source-to-background ratios: influence of reconstruction algorithms. Radiother Oncol 69 (2003) 247-250
23. Grégoire V., Coche E., Cosnard G., et al. Selection and delineation of lymph node target volumes in head and neck conformal radiotherapy. Proposal for standardizing terminology and procedure based on the surgical experience. Radiother Oncol 56 (2000) 135-150
24. Sherouse G.W., Thorn J., Novins K., et al. A portable 3D radiotherapy design system. [Abstract]. Med Phys 16 (1989) 466
25. De Gersem W., Claus F., De Wagter C., et al. An anatomy-based beam segmentation tool for intensity-modulated radiation therapy and its application to head-and-neck cancer. Int J Radiat Oncol Biol Phys 51 (2001) 849-859
26. De Gersem W., Claus F., De Wagter C., et al. Leaf position optimization for step-and-shoot IMRT. Int J Radiat Oncol Biol Phys 51 (2001) 1371-1388
27. De Neve W., De Gersem W., De Meerleer G., et al. In response to Drs. Vaarkamp and Krasin. Int J Radiat Oncol Biol Phys 49 (2001) 1519-1520
28. De Neve W., De Gersem W., Derycke S., et al. Clinical delivery of intensity modulated conformal radiotherapy for relapsed or second-primary head and neck cancer using a multileaf collimator with dynamic control. Radiother Oncol 50 (1999) 301-314
29. National Cancer Institute. The revised common toxicity criteria, version 2. CTEP website: http://ctep.info.nih.gov/reporting/ctc.html.
30. Therasse P., Arbuck S.G., Eisenhauer E.A., et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 92 (2000) 205-216
31. LENT SOMA scales for all anatomic sites. Int J Radiat Oncol Biol Phys 31 (1995) 1049-1091
32. De Neve W., Wu Y., and Ezzel G. Practical IMRT planning. In: Bortfeld T., Schmidt-Ulrich R., De Neve W., and Wazer D. (Eds). Image-guided IMRT (2006), Springer-Verlag, Berlin 47-59
33. Lee S.P., Leu M.Y., Smathers J.B., et al. Biologically effective dose distribution based on the linear quadratic model and its clinical relevance. Int J Radiat Oncol Biol Phys 33 (1995) 375-389