Particle design of indomethacin using a four-fluid-nozzle spray-drying technique

Journal of Drug Delivery Science and Technology

Volumn 17, Issue 2, 2007, Pages 129-135

  Chen, R ^a   Okamoto, H ^b   Danjo, K ^b  

^a Mintai Chemical Co Ltd   (Taiwan)

^b MEIJO UNIVERSITY   (Japan)

Author keywords

Amorphous; HPMC; Indomethacin; Solid dispersion; Solubility; Spray drying

Indexed keywords

DRUG CARRIER; HYDROXYPROPYLMETHYLCELLULOSE; INDOMETACIN;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CRYSTAL STRUCTURE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DESIGN; DRUG MANUFACTURE; DRUG RELEASE; DRUG SOLUBILITY; MELTING POINT; MORPHOLOGY; NEBULIZATION; PARTICLE SIZE; PH MEASUREMENT; POWDER; SCANNING ELECTROCHEMICAL MICROSCOPY; SOLID STATE; SPRAY DRYING; X RAY DIFFRACTION;

EID: 34247115068     PISSN: 17732247     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1773-2247(07)50020-1     Document Type: Article

References (18)

1. Simonelli A.P., Mehta S.C., Higuchi W.I. - Dissolution rates of high energy polyvinylpyrrolidone (PVP)-sulfathiazole coprecipitates. - J. Pharm. Sci., 58, 538-549, 1969.
2. Simonelli A.P., Mehta S.C., Higuchi W.I. - Dissolution rates of high energy sulfathiazole-povidone coprecipitates. II. Characterization of form of drug controlling its dissolution rate via solubility studies. - J. Pharm. Sci., 65, 355-361, 1976.
3. McGinity J.W., Maincent P., Steinfink H. - Crystallinity and dissolution rate of tolbutamide solid dispersions prepared by the melt method. - J. Pharm. Sci., 73, 1441-1444, 1984.
4. Law S.L., Lo W.Y., Lin F.M., Chaing C.H. - Dissolution and absorption of nifedipine in polyethylene glycol solid dispersion containing phosphatidylcholine. - Int. J. Pharm., 84, 161-166, 1992.
5. Mura P., Manderioli A., Bramanti G., Ceccarelli L. - Properties of solid dispersions of naproxen in various polyethylene glycols. - Drug Dev. Ind. Pharm., 22, 909-916, 1996.
6. Kumar S.G.V., Mishrad D.N. - Preparation, characterization and in vitro dissolution studies of solid dispersion of meloxicam with peg 6000. - Yakugaku Zasshi, 126, 657-664, 2006.
7. Sekikawa H., Naganuma T., Fujiwara J., Nakano M., Arita T. - Dissolution behaviors and gastrointestinal absorption of tolbutamide in tolbutamide- polyvinylpyrrolidone coprecipitate. - Chem. Pharm. Bull., 27, 31-37, 1979.
8. Itoh S., Tagaki A., Tanabe K., Yamazaki M. - Improvement of rectal absorption of mefenamic acid using microenvironmental pH-controlled solid dispersion with polyvinylpyrrolidone. - Yakuzaigaku, 54, 180-184, 1994.
9. Lo W.Y., Law S.L. - Dissolution behavior of griseofulvin solid dispersions using polyethylene glycol, talc, and their combination as dispersion carriers. - Drug Develop. Ind. Pharm., 22, 231-236, 1996.
10. Tantishaiyakul V., Kaewnopparat N., Ingkatawornwong S. - Properties of solid dispersions of piroxicam in polyvinylpyrrolidone K-30. - Int. J. Pharm., 143, 59-66, 1996.
11. Ozeki T., Yuasa H., Kanaya Y., Oishi K. - Application of the solid dispersion method to the controlled release of medicine. VII. Release mechanism of a highly water-soluble medicine from solid dispersion with different molecular weights of polymer. - Chem. Pharm. Bull., 43, 660-665, 1995.
12. Corrigan O.I., Holohan E.M. - Amorphous spray-dried hydroflumethiazide- polyvinylpyrrolidone systems: physiochemical properties. - J. Pharm. Pharmacol., 36, 217-221, 1984.
13. Corrigan O.I., Holohan E.M., Reilly M.R. - Physicochemical properties of indomethacin and related compounds co-spray dried with polyvinylpyrrolidone. - Drug Develop. Ind. Pharm., 11, 677-695, 1985.
14. Hirasawa N., Danjo K., Haruna M., Otsuka A. - Physicochemical characterization and drug release studies of naproxen solid dispersions using lactose as a carrier. - Chem. Pharm. Bull., 46, 1027-1030, 1998.
15. Hirasawa N., Okamoto H., Danjo K. - Lactose as a low molecular weight carrier of solid dispersions for carbamazepine and ethenzamide. - Chem. Pharm. Bull., 47, 417-420, 1999.
16. Chen R., Tagawa M., Hoshi N., Ogura T., Okamoto H., Danjo K. - Improved dissolution of an insoluble drug using a 4-fluid nozzle spray-drying technique. - Chem. Pharm. Bull., 52, 1066-1070, 2004.
17. Chen R., Okamoto H., Danjo K. - Particle design using a 4-fluid-nozzle spray-drying technique for sustained release of acetaminophen. - Chem. Pharm. Bull., 54, 948-953, 2006.
18. Taylor L.S., Zografi G. - Spectroscopic characterization of interactions between PVP and indomethacin in amorphous molecular dispersions. - Pharm. Research, 14, 1691-1698, 1997.