Particle design using a 4-fluid-nozzle spray-drying technique for sustained release of acetaminophen

Chemical and Pharmaceutical Bulletin

Volumn 54, Issue 7, 2006, Pages 948-953

  Chen, Richer ^a   Okamoto, Hirokazu ^b   Danjo, Kazumi ^b  

^a Mintai Chemical Co Ltd   (Taiwan)

^b MEIJO UNIVERSITY   (Japan)

Author keywords

Acetaminophen; Chitosan; Solid dispersion; Spray drying; Sustained release

Indexed keywords

AMINO ACID; CARBONYL DERIVATIVE; CHITOSAN; PARACETAMOL;

ALKALINITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL ANALYSIS; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DISSOLUTION; DRUG DELIVERY SYSTEM; DRUG INTERACTION; DRUG RELEASE; HEATING; HYDROGEN BOND; INFRARED SPECTROSCOPY; MORPHOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH; SCANNING ELECTRON MICROSCOPY; SOLID STATE; SPRAY DRYING; SUSTAINED DRUG RELEASE; X RAY DIFFRACTION;

ACETAMINOPHEN; CHITOSAN; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; TECHNOLOGY, PHARMACEUTICAL;

EID: 33745685692     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.54.948     Document Type: Article

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