In Pursuit of the Ultimate: The Initial Ahmedabad Journey Toward Transplantation Tolerance

Transplantation Proceedings

Volumn 39, Issue 3, 2007, Pages 653-657

  Trivedi, H L ^a   Vanikar, A V ^b   Modi, P R ^a   Shah, P R ^a   Shah, V R ^a   Trivedi, V B ^b  

^a Gulabben Rasiklal Doshi and Kamlaben Mafatlal Mehta Institute   (India)

^b Transfusion Services and Immunohematology ^*  (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIBODY; AZATHIOPRINE; CREATININE; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISOLONE; T LYMPHOCYTE ANTIBODY; TACROLIMUS;

ADD ON THERAPY; ADOLESCENT; ADULT; AGED; ARTICLE; BONE MARROW; CD34 SELECTION; CELL COUNT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DESENSITIZATION; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLOW UP; GRAFT RECIPIENT; GRAFT REJECTION; GRAFT VERSUS HOST REACTION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; INFUSION; IRRADIATION; KIDNEY TRANSPLANTATION; LEUKOCYTE; LIVER; LIVING DONOR; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; NONMYELOABLATIVE CONDITIONING; PERIPHERAL BLOOD STEM CELL; PRIORITY JOURNAL; SCHOOL CHILD; SURVIVAL; THYMUS; TRANSPLANTATION TOLERANCE;

ADOLESCENT; ADULT; AGED; BONE MARROW CELLS; CHILD; GRAFT SURVIVAL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOCOMPATIBILITY TESTING; HUMANS; IMMUNOSUPPRESSION; INDIA; MIDDLE AGED; TISSUE DONORS; TRANSPLANTATION CHIMERA; TRANSPLANTATION TOLERANCE;

EID: 34247094145     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2007.01.064     Document Type: Article

References (20)

1. Tomita Y., Yoshikawa M., Zhang Q.W., et al. Induction of permanent mixed chimerism and skin allograft tolerance across fully MHC mismatched barriers by the additional myelosuppressive treatments in mice primed with allogeneic spleen cells followed by cyclophosphamide. J Immunol 164 (2000) 34
2. Van Pel M., van Breugel D.W.J.G., Vos W., et al. Towards a myeloablative regime with clinical potential: I. Treosulfan conditioning and bone marrow transplantation allow induction of donor-specific tolerance for skin grafts across full MHC barriers. Bone Marrow Transplant 32 (2003) 15
3. Gorczynski R., Chen Z., Zeng H., et al. Specificity for in-vivo graft prolongation in gamma delta T-cell receptor hybridoma derived from mice given portal vein donor-specific pre-immunization and skin allografts. J Immunol 159 (1997) 3698
4. Racusen L.C., Solez K., Colvin R.B., et al. The Banff 97 working classification of renal allograft pathology. Kidney Int 55 (1999) 713
5. Owen R.D. Immunogenetic consequences of vascular anastomoses between bovine twins. Science 102 (1945) 400
6. Anderson D., Billingham R.E., Lampkin G.H., et al. Tolerance of homografts twin diagnosis and the freemartin conditions in cattle. Heredity 6 (1952) 210
7. Billingham R.E., Brent L., and Medawar P.B. "Actively acquired tolerance" of foreign cells. Nature 172 (1953) 603
8. Slavin S., Strober S., Fukes Z., et al. Induction of specific tissue transplantation tolerance using fractionated total lymphoid irradiation in adult mice; long term survival of allogeneic bone marrow and skin grafts. J Exp Med 146 (1977) 34
9. Sykes M., and Spitzer T.R. Protecting the host naturally. Nat Med 11 (2005) 1164
10. Trivedi H.L., Shah V.R., Shah P.R., et al. Mega-dose approach to PBSC infusion induced allograft hypo-responsiveness in living-related renal allograft recipients. Transplant Proc 33 (2001) 71
11. Trivedi H.L., Shah V.R., Vanikar A.V., et al. High dose allogeneic PBSC infusion-a strategy to induce allograft hypo-responsiveness in pediatric renal transplant recipients. Pediatr Transplant 6 (2002) 63
12. Trivedi H.L., Vanikar A.V., Shah V.R., et al. Mega dose unfractionated donor bone marrow derived cell infusion in thymus and periphery-an integrated clinical approach for tolerance in live related renal allograft. Transplant Proc 35 (2003) 203
13. Trivedi H.L., Vanikar A.V., Modi P.R., et al. Allogeneic hematopoietic stem cell transplantation, mixed chimerism and tolerance in living-related donor renal allograft recipients. Transplant Proc 37 (2005) 737
14. Kushida T., Inaba M., Hisha H., et al. Crucial role of donor-derived stromal cells in successful treatment for intractable autoimmune diseases in MRL/lpr mice by BMT via portal vein. Stem Cells 19 (2001) 226
15. Trivedi H.L., Shah V.R., Shah P.R., et al. High dose PBSC associated tolerance in live-related renal allograft recipients. Transplant Proc 32 (2000) 2001
16. Posselt A.M., Barker C.F., Tomaszewski J.E., et al. Induction of donor-specific unresponsiveness by intrathymic islet transplantation. Science 249 (1990) 1293
17. Nakamura K., Inaba M., Sugiura K., et al. Enhancement of allogeneic hematopoietic stem cell engraftment and prevention of GVHD by intra-bone marrow bone marrow transplantation plus donor lymphocyte infusion. Stem Cells 22 (2004) 125
18. Calne R.Y., Friend P.J., Moffatt S., et al. Prope tolerance, perioperative Campath IH, and low dose cyclosporine monotherapyin renal allograft recipients. [letter]. Lancet 351 (1998) 1701
19. Starzl T.E., and Zinkernagel R.M. Antigen localization and migration in immunity and tolerance. N Engl J Med 339 (1998) 1905
20. + T cell repertoire. J Clin Invest 116 (2006) 156