Analysis of inhibition rate enhancement by covalent linkage of antithrombin to heparin as a potential predictor of reaction mechanism

Journal of Biochemistry

Volumn 141, Issue 1, 2007, Pages 25-35

  Patel, Sanjay ^a   Berry, Leslie R ^a,b   Chan, Anthony K C ^a,b,c  

^a HENDERSON RESEARCH CENTRE   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Anticoagulant; Antithrombin; Coagulation factor; Heparin; Mechanism

Indexed keywords

ANTITHROMBIN; BLOOD CLOTTING FACTOR 11A; BLOOD CLOTTING FACTOR 7A; BLOOD CLOTTING FACTOR 9A; CALCIUM ION; HEPARIN; HEPARINOID; LIPID; PROTEINASE; THROMBIN; THROMBOPLASTIN;

ARTICLE; BINDING AFFINITY; CATALYSIS; CONFORMATION; COVALENT BOND; DRUG ACTIVITY; DRUG BINDING; DRUG MECHANISM; DRUG PROTEIN BINDING; ENZYME INHIBITION; REACTION ANALYSIS;

ANTITHROMBINS; BLOOD COAGULATION FACTORS; FACTOR IXA; FACTOR VIIA; FACTOR XIA; HEAT; HEPARIN; KINETICS; THROMBIN; THROMBOPLASTIN;

EID: 34147220888     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/jb/mvm001     Document Type: Article

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