Quantitative LC/MS/MS method and in vivo pharmacokinetic studies of vitexin rhamnoside, a bioactive constituent on cardiovascular system from hawthorn

Biomedical Chromatography

Volumn 21, Issue 4, 2007, Pages 422-429

  Liang, Mingjin ^a   Xu, Wen ^a   Zhang, Weidong ^a,b   Zhang, Chuan ^a   Liu, Runhui ^a   Shen, Yunheng ^a   Li, Huiliang ^a   Wang, Xiaolin ^c   Wang, Xiangwei ^c   Pan, Qiongqun ^c   Chen, Chunlin ^c  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c Shanghai Medicilon Inc   (China)

Author keywords

Bioavailability; LC MS MS; Pharmacokinetics; Vitexin rhamnoside

Indexed keywords

BIOCHEMISTRY; CARDIOVASCULAR SYSTEM; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NEGATIVE IONS; RATS;

BIOACTIVES; BIOAVAILABILITY; IN-VIVO; INTRAVENOUS ADMINISTRATION; LC-MS-MS; LC.MS/MS; ORAL ADMINISTRATION; PHARMACOKINETIC STUDIES; VITEXIN RHAMNOSIDE; VIVO PHARMACOKINETICS;

PHARMACOKINETICS;

FLAVONOID; METHANOL; UNCLASSIFIED DRUG; VITEXIN; VITEXIN GLUCOSIDE; VITEXIN RHAMNOSIDE;

ACCURACY; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; CARDIOVASCULAR SYSTEM; CHEMICAL REACTION; CONTROLLED STUDY; CRATAEGUS; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG METABOLISM; DRUG STRUCTURE; ELUTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PILOT STUDY; PRECIPITATION; QUANTITATIVE ANALYSIS; RAT; SEPARATION TECHNIQUE; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

CRATAEGUS; RATTUS;

EID: 34147200277     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.777     Document Type: Article

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