Secondary palatal closure in rats in association with relative maternofetal levels of folic acid, vitamin B12, and homocysteine

Annals of Anatomy

Volumn 189, Issue 3, 2007, Pages 229-233

  Weingärtner, Jens ^a   Maile, Sergei ^a   Proff, Peter ^a   Reicheneder, Claudia ^a   Bienengräber, Volker ^b   Fanghänel, Jochen ^a   Gedrange, Tomas ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

Folic acid; Homocysteine; Secondary palatal closure; Vitamin B12

Indexed keywords

CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE;

AMINO ACID BLOOD LEVEL; AMNION FLUID LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; FETOPLACENTAL UNIT; FOLIC ACID BLOOD LEVEL; MATERNAL BLOOD; NONHUMAN; PALATE MALFORMATION; PREGNANCY; RAT; RISK FACTOR; SKULL DEVELOPMENT;

ANIMALIA; RATTUS;

EID: 34147192049     PISSN: 09409602     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aanat.2006.10.006     Document Type: Article

References (18)

1. Breitsprecher L., Fanghänel J., Metelmann H.R., Mlynski G., Wurfel F., Freise K., and Knape U. The influence of the muscles of facial expression on the development of the midface and the nose in cleft lip and palate patients. A reflection of functional anatomy, facial ethetics and physiology of the nose. Ann. Anat. 181 (1999) 19-25
2. Breitsprecher L., Fanghänel J., Noe A., Lockett E., and Raab U. The functional anatomy of the muscles of facial expression in humans with and without cleft lip and palate. A contribution to refine muscle reconstruction in primary cheilo- and rhinoplasties in patients with uni- and bilateral complete CLP. Ann. Anat. 184 (2002) 27-34
3. Copp A.J. Prevention of neural tube defects: vitamins, enzymes and genes. Curr. Opin. Neurol. 11 (1998) 97-102
4. Eskes T.K.A.B. Folates and the fetus. Eur. J. Obstet. Gynecol. Reprod. Biol. 71 (1997) 105-111
5. Eskes T.K.A.B. Open or closed. Eur. J. Obstet. Reprod. Biol. 78 (1998) 169-177
6. Fanghänel J., Gedrange T., and Proff P. The face-physiognomic expressiveness and human identity. Ann. Anat. 188 (2006) 261-266
7. Gesch D., and Kirbschus A. Complete cleft lip and palate without bone grafting and its effect on craniofacial morphology in three planes. Ann. Anat. 186 (2004) 531-537
8. Herrmann W., Schorr H., Geisel J., and Riegel W. Homocysteine, cystathionine, methylmalonic acid and B-vitamins in patients with renal diseases. Clin. Chem. Lab. Med. 39 (2001) 739-746
9. Hol F.A., von der Put N.M.J., Geurds M.P.A., Heil S.G., Trijbels F.J.M., Hamel B.C.J., Mariman E.C.M., and Blom H.J. Molecular genetic of the gene encoding in trifunctional enzyme MTHFD (methylenetetrahydrofolate-dehydrogenase, methenyltetrahdrofolyte-cyclohydrolase, formyltetrahydrofolate-synthetase) in patients with neural tube defects. Clin. Genet. 52 (1998) 119-125
10. Mason J.B., and Miller J.W. The effects of vitamin B12, B6, and folate on blood homocysteine levels. Ann. NY Acad. Sci. 30 (1992) 197-203
11. Naurath H.J., Joosten E., Riezler R., Stabler S.P., Allen R.H., and Lindenbaum J. Effects of vitamin B12, folate, and vitamin B6 supplements in elderly people with normal serum vitamin concentrations. Lancet 8 (1995) 85-89
12. Ngyuyen T.T., Hayakawa T., and Tsuge H. Effects of vitamin B6 deficiency on the synthesis and accumulation of S-adenosylhomocysteine and S-adenosylmethionine in rat tissues. J. Nutr. Sci. Vitaminol. 47 (2001) 188-194
13. Niculescu M.D., and Zeisel S.H. Diet, methyl donors and DNA methylation: interactions between dietary folate, methionine and choline. J. Nutr. 132 (2002) 2333-2335
14. Pietrzik K., Prinz-Langenohl R., and Thorand B. Micronutrients in pregnancy. Z. Geburtsh. Neonatol. 201 (1997) 21-24
15. Selhub J. Folate, vitamin B12 and vitamin B6 and one carbon metabolism. J. Nutr. Aging 6 (2002) 39-42
16. Stampfer M.J., and Willett W.C. Homocysteine and marginal vitamin deficiency. The importance of adequate vitamin intake. JAMA 270 (1993) 2726-2727
17. Stanger O., Hermann W., Pietrzik K., Fowler B., Geisel J., Dierkes J., and Weger M. Konsensuspapier der D.A.CH.-Liga Homocystein über den rationellen klinischen Umgang mit Homocystein, Folsäure und B-Vitaminen bei kardiovaskulären und thrombotischen Erkrankungen - Richtlinien und Empfehlungen. J. Kardiol. 10 (2003) 190-199
18. Steegers-Theunissen R.P.M., Smithells R.W., and Eskes T.K. Update of new risk factors and prevention of neural-tube defects. Obstet. Gynecol. Survey 48 (1993) 293-298