-
1
-
-
27644483064
-
Regulatory networks in embryo-derived pluripotent stem cells
-
Boiani M., and Scholer H.R. Regulatory networks in embryo-derived pluripotent stem cells. Nat Rev Mol Cell Biol 6 (2005) 872-884
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 872-884
-
-
Boiani, M.1
Scholer, H.R.2
-
2
-
-
33748425154
-
Guiding embryonic stem cells towards differentiation: lessons from molecular embryology
-
Spagnoli F.M., and Hemmati-Brivanlou A. Guiding embryonic stem cells towards differentiation: lessons from molecular embryology. Curr Opin Genet Dev 16 (2006) 469-475
-
(2006)
Curr Opin Genet Dev
, vol.16
, pp. 469-475
-
-
Spagnoli, F.M.1
Hemmati-Brivanlou, A.2
-
3
-
-
23944457397
-
Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells
-
Cowan C.A., Atienza J., Melton D.A., and Eggan K. Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells. Science 309 (2005) 1369-1373
-
(2005)
Science
, vol.309
, pp. 1369-1373
-
-
Cowan, C.A.1
Atienza, J.2
Melton, D.A.3
Eggan, K.4
-
4
-
-
0037130207
-
A molecular programme for the specification of germ cell fate in mice
-
Saitou M., Barton S.C., and Surani M.A. A molecular programme for the specification of germ cell fate in mice. Nature 418 (2002) 293-300
-
(2002)
Nature
, vol.418
, pp. 293-300
-
-
Saitou, M.1
Barton, S.C.2
Surani, M.A.3
-
5
-
-
0035499457
-
Reprogramming of genome function through epigenetic inheritance
-
Surani M.A. Reprogramming of genome function through epigenetic inheritance. Nature 414 (2001) 122-128
-
(2001)
Nature
, vol.414
, pp. 122-128
-
-
Surani, M.A.1
-
6
-
-
0019826665
-
MH: Establishment in culture of pluripotential cells from mouse embryos
-
Evans M.K. MH: Establishment in culture of pluripotential cells from mouse embryos. Nature 292 (1981) 154-156
-
(1981)
Nature
, vol.292
, pp. 154-156
-
-
Evans, M.K.1
-
7
-
-
0001007610
-
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
-
Martin G.R. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci USA 78 (1981) 7634-7638
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 7634-7638
-
-
Martin, G.R.1
-
8
-
-
0036709213
-
Signalling, cell cycle and pluripotency in embryonic stem cells
-
Burdon T., Smith A., and Savatier P. Signalling, cell cycle and pluripotency in embryonic stem cells. Trends Cell Biol 12 (2002) 432-438
-
(2002)
Trends Cell Biol
, vol.12
, pp. 432-438
-
-
Burdon, T.1
Smith, A.2
Savatier, P.3
-
9
-
-
18844396119
-
Embryonic stem cell differentiation: emergence of a new era in biology and medicine
-
Keller G. Embryonic stem cell differentiation: emergence of a new era in biology and medicine. Genes Dev 19 (2005) 1129-1155
-
(2005)
Genes Dev
, vol.19
, pp. 1129-1155
-
-
Keller, G.1
-
10
-
-
0033638174
-
Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity
-
Kawasaki H., Mizuseki K., Nishikawa S., Kaneko S., Kuwana Y., Nakanishi S., Nishikawa S.I., and Sasai Y. Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron 28 (2000) 31-40
-
(2000)
Neuron
, vol.28
, pp. 31-40
-
-
Kawasaki, H.1
Mizuseki, K.2
Nishikawa, S.3
Kaneko, S.4
Kuwana, Y.5
Nakanishi, S.6
Nishikawa, S.I.7
Sasai, Y.8
-
11
-
-
33747619377
-
Derivation and characterization of neuronal precursors and dopaminergic neurons from human embryonic stem cells in vitro
-
Carpenter M., Rao M.S., Freed W., and Zeng X. Derivation and characterization of neuronal precursors and dopaminergic neurons from human embryonic stem cells in vitro. Methods Mol Biol 331 (2006) 153-167
-
(2006)
Methods Mol Biol
, vol.331
, pp. 153-167
-
-
Carpenter, M.1
Rao, M.S.2
Freed, W.3
Zeng, X.4
-
12
-
-
0037313844
-
Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture
-
Ying Q.L., Stavridis M., Griffiths D., Li M., and Smith A. Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nat Biotechnol 21 (2003) 183-186
-
(2003)
Nat Biotechnol
, vol.21
, pp. 183-186
-
-
Ying, Q.L.1
Stavridis, M.2
Griffiths, D.3
Li, M.4
Smith, A.5
-
13
-
-
0035025619
-
Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism
-
Tropepe V., Hitoshi S., Sirard C., Mak T.W., Rossant J., and van der Kooy D. Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism. Neuron 30 (2001) 65-78
-
(2001)
Neuron
, vol.30
, pp. 65-78
-
-
Tropepe, V.1
Hitoshi, S.2
Sirard, C.3
Mak, T.W.4
Rossant, J.5
van der Kooy, D.6
-
14
-
-
0037106657
-
Normal timing of oligodendrocyte development from genetically engineered, lineage-selectable mouse ES cells
-
Billon N., Jolicoeur C., Ying Q.L., Smith A., and Raff M. Normal timing of oligodendrocyte development from genetically engineered, lineage-selectable mouse ES cells. J Cell Sci 115 (2002) 3657-3665
-
(2002)
J Cell Sci
, vol.115
, pp. 3657-3665
-
-
Billon, N.1
Jolicoeur, C.2
Ying, Q.L.3
Smith, A.4
Raff, M.5
-
15
-
-
0028907753
-
Embryonic stem cells express neuronal properties in vitro
-
Bain G., Kitchens D., Yao M., Huettner J.E., and Gottlieb D.I. Embryonic stem cells express neuronal properties in vitro. Dev Biol 168 (1995) 342-357
-
(1995)
Dev Biol
, vol.168
, pp. 342-357
-
-
Bain, G.1
Kitchens, D.2
Yao, M.3
Huettner, J.E.4
Gottlieb, D.I.5
-
16
-
-
1842689282
-
Regionalization and fate specification in neurospheres: the role of Olig2 and Pax6
-
Hack M.A., Sugimori M., Lundberg C., Nakafuku M., and Gotz M. Regionalization and fate specification in neurospheres: the role of Olig2 and Pax6. Mol Cell Neurosci 25 (2004) 664-678
-
(2004)
Mol Cell Neurosci
, vol.25
, pp. 664-678
-
-
Hack, M.A.1
Sugimori, M.2
Lundberg, C.3
Nakafuku, M.4
Gotz, M.5
-
17
-
-
0842277732
-
Neuronal differentiation following transplantation of expanded mouse neurosphere cultures derived from different embryonic forebrain regions
-
Eriksson C., Bjorklund A., and Wictorin K. Neuronal differentiation following transplantation of expanded mouse neurosphere cultures derived from different embryonic forebrain regions. Exp Neurol 184 (2003) 615-635
-
(2003)
Exp Neurol
, vol.184
, pp. 615-635
-
-
Eriksson, C.1
Bjorklund, A.2
Wictorin, K.3
-
18
-
-
24944484633
-
Niche-independent symmetrical self-renewal of a mammalian tissue stem cell
-
Paper describing the derivation of clonogenic, self renewing neural stem cells from mouse and human ES cells. These cells can be differentiated into glial and neuronal progeny, making them useful as models for neural differentiation.
-
Conti L., Pollard S.M., Gorba T., Reitano E., Toselli M., Biella G., Sun Y., Sanzone S., Ying Q.L., Cattaneo E., et al. Niche-independent symmetrical self-renewal of a mammalian tissue stem cell. PLoS Biol 3 (2005) e283. Paper describing the derivation of clonogenic, self renewing neural stem cells from mouse and human ES cells. These cells can be differentiated into glial and neuronal progeny, making them useful as models for neural differentiation.
-
(2005)
PLoS Biol
, vol.3
-
-
Conti, L.1
Pollard, S.M.2
Gorba, T.3
Reitano, E.4
Toselli, M.5
Biella, G.6
Sun, Y.7
Sanzone, S.8
Ying, Q.L.9
Cattaneo, E.10
-
19
-
-
0345874402
-
FGF-dependent generation of oligodendrocytes by a hedgehog-independent pathway
-
Chandran S., Kato H., Gerreli D., Compston A., Svendsen C.N., and Allen N.D. FGF-dependent generation of oligodendrocytes by a hedgehog-independent pathway. Development 130 (2003) 6599-6609
-
(2003)
Development
, vol.130
, pp. 6599-6609
-
-
Chandran, S.1
Kato, H.2
Gerreli, D.3
Compston, A.4
Svendsen, C.N.5
Allen, N.D.6
-
20
-
-
0036942868
-
Regional specification of neurosphere cultures derived from subregions of the embryonic telencephalon
-
Parmar M., Skogh C., Bjorklund A., and Campbell K. Regional specification of neurosphere cultures derived from subregions of the embryonic telencephalon. Mol Cell Neurosci 21 (2002) 645-656
-
(2002)
Mol Cell Neurosci
, vol.21
, pp. 645-656
-
-
Parmar, M.1
Skogh, C.2
Bjorklund, A.3
Campbell, K.4
-
21
-
-
33947587879
-
Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures
-
10.1182/blood-2006-09-047704
-
Kennedy M., D'Souza S.L., Lynch-Kattman M., Schwantz S., and Keller G. Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures. Blood (2006) 10.1182/blood-2006-09-047704
-
(2006)
Blood
-
-
Kennedy, M.1
D'Souza, S.L.2
Lynch-Kattman, M.3
Schwantz, S.4
Keller, G.5
-
22
-
-
0041827036
-
Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation
-
Fehling H.J., Lacaud G., Kubo A., Kennedy M., Robertson S., Keller G., and Kouskoff V. Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation. Development 130 (2003) 4217-4227
-
(2003)
Development
, vol.130
, pp. 4217-4227
-
-
Fehling, H.J.1
Lacaud, G.2
Kubo, A.3
Kennedy, M.4
Robertson, S.5
Keller, G.6
Kouskoff, V.7
-
23
-
-
0031833476
-
Progressive lineage analysis by cell sorting and culture identifies FLK1+VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages
-
Nishikawa S.I., Nishikawa S., Hirashima M., Matsuyoshi N., and Kodama H. Progressive lineage analysis by cell sorting and culture identifies FLK1+VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages. Development 125 (1998) 1747-1757
-
(1998)
Development
, vol.125
, pp. 1747-1757
-
-
Nishikawa, S.I.1
Nishikawa, S.2
Hirashima, M.3
Matsuyoshi, N.4
Kodama, H.5
-
24
-
-
33644856140
-
Functions of histone-modifying enzymes in development
-
Lin W., and Dent S.Y. Functions of histone-modifying enzymes in development. Curr Opin Genet Dev 16 (2006) 137-142
-
(2006)
Curr Opin Genet Dev
, vol.16
, pp. 137-142
-
-
Lin, W.1
Dent, S.Y.2
-
26
-
-
8844265508
-
Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins
-
Ringrose L., and Paro R. Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins. Annu Rev Genet 38 (2004) 413-443
-
(2004)
Annu Rev Genet
, vol.38
, pp. 413-443
-
-
Ringrose, L.1
Paro, R.2
-
27
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Genome-wide ChIP analysis of histone modifications in mouse ES cells. The authors provided evidence for the co-existence of repressive H3K27me3 and active H3K4me3 marking developmental regulator genes.
-
Bernstein B.E., Mikkelsen T.S., Xie X., Kamal M., Huebert D.J., Cuff J., Fry B., Meissner A., Wernig M., Plath K., et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125 (2006) 315-326. Genome-wide ChIP analysis of histone modifications in mouse ES cells. The authors provided evidence for the co-existence of repressive H3K27me3 and active H3K4me3 marking developmental regulator genes.
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
Mikkelsen, T.S.2
Xie, X.3
Kamal, M.4
Huebert, D.J.5
Cuff, J.6
Fry, B.7
Meissner, A.8
Wernig, M.9
Plath, K.10
-
28
-
-
33646872978
-
Chromatin signatures of pluripotent cell lines
-
Analysis of the epigenetic features of mouse ES cells in which the authors show that opposing H3K9ac and H3K27me3 modification at the promoters of developmental regulator genes in ES cells maintains genes in poised state.
-
Azuara V., Perry P., Sauer S., Spivakov M., Jorgensen H.F., John R.M., Gouti M., Casanova M., Warnes G., Merkenschlager M., et al. Chromatin signatures of pluripotent cell lines. Nat Cell Biol 8 (2006) 532-538. Analysis of the epigenetic features of mouse ES cells in which the authors show that opposing H3K9ac and H3K27me3 modification at the promoters of developmental regulator genes in ES cells maintains genes in poised state.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 532-538
-
-
Azuara, V.1
Perry, P.2
Sauer, S.3
Spivakov, M.4
Jorgensen, H.F.5
John, R.M.6
Gouti, M.7
Casanova, M.8
Warnes, G.9
Merkenschlager, M.10
-
29
-
-
33746640565
-
Stem cells primed for action: Polycomb repressive complexes restrain the expression of lineage-specific regulators in embryonic stem cells
-
Jorgensen H.F., Giadrossi S., Casanova M., Endoh M., Koseki H., Brockdorff N., and Fisher A.G. Stem cells primed for action: Polycomb repressive complexes restrain the expression of lineage-specific regulators in embryonic stem cells. Cell Cycle 5 (2006) 1411-1414
-
(2006)
Cell Cycle
, vol.5
, pp. 1411-1414
-
-
Jorgensen, H.F.1
Giadrossi, S.2
Casanova, M.3
Endoh, M.4
Koseki, H.5
Brockdorff, N.6
Fisher, A.G.7
-
30
-
-
33646865180
-
Control of developmental regulators by Polycomb in human embryonic stem cells
-
Identification of Polycomb target genes in human ES cells, showing that Suz12, a PRC2 subunit, binds a large number of promoters of regulatory genes important for subsequent development. The authors demonstrate that many of these loci are co-occupied by Oct4, Nanog and Sox2.
-
Lee T.I., Jenner R.G., Boyer L.A., Guenther M.G., Levine S.S., Kumar R.M., Chevalier B., Johnstone S.E., Cole M.F., Isono K., et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 125 (2006) 301-313. Identification of Polycomb target genes in human ES cells, showing that Suz12, a PRC2 subunit, binds a large number of promoters of regulatory genes important for subsequent development. The authors demonstrate that many of these loci are co-occupied by Oct4, Nanog and Sox2.
-
(2006)
Cell
, vol.125
, pp. 301-313
-
-
Lee, T.I.1
Jenner, R.G.2
Boyer, L.A.3
Guenther, M.G.4
Levine, S.S.5
Kumar, R.M.6
Chevalier, B.7
Johnstone, S.E.8
Cole, M.F.9
Isono, K.10
-
31
-
-
33646882068
-
Polycomb complexes repress developmental regulators in murine embryonic stem cells
-
Identification of Polycomb target genes in mouse ES cells, showing that many developmental regulator genes bind PRC2. The authors demonstrate that removal of the PRC2 component Eed results in gene de-repression.
-
Boyer L.A., Plath K., Zeitlinger J., Brambrink T., Medeiros L.A., Lee T.I., Levine S.S., Wernig M., Tajonar A., Ray M.K., et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 441 (2006) 349-353. Identification of Polycomb target genes in mouse ES cells, showing that many developmental regulator genes bind PRC2. The authors demonstrate that removal of the PRC2 component Eed results in gene de-repression.
-
(2006)
Nature
, vol.441
, pp. 349-353
-
-
Boyer, L.A.1
Plath, K.2
Zeitlinger, J.3
Brambrink, T.4
Medeiros, L.A.5
Lee, T.I.6
Levine, S.S.7
Wernig, M.8
Tajonar, A.9
Ray, M.K.10
-
32
-
-
25144525014
-
Core transcriptional regulatory circuitry in human embryonic stem cells
-
Boyer L.A., Lee T.I., Cole M.F., Johnstone S.E., Levine S.S., Zucker J.P., Guenther M.G., Kumar R.M., Murray H.L., Jenner R.G., et al. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122 (2005) 947-956
-
(2005)
Cell
, vol.122
, pp. 947-956
-
-
Boyer, L.A.1
Lee, T.I.2
Cole, M.F.3
Johnstone, S.E.4
Levine, S.S.5
Zucker, J.P.6
Guenther, M.G.7
Kumar, R.M.8
Murray, H.L.9
Jenner, R.G.10
-
33
-
-
33745258986
-
Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster
-
Tolhuis B., de Wit E., Muijrers I., Teunissen H., Talhout W., van Steensel B., and van Lohuizen M. Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster. Nat Genet 38 (2006) 694-699
-
(2006)
Nat Genet
, vol.38
, pp. 694-699
-
-
Tolhuis, B.1
de Wit, E.2
Muijrers, I.3
Teunissen, H.4
Talhout, W.5
van Steensel, B.6
van Lohuizen, M.7
-
34
-
-
33745225872
-
Genome-wide analysis of Polycomb targets in Drosophila melanogaster
-
Schwartz Y.B., Kahn T.G., Nix D.A., Li X.Y., Bourgon R., Biggin M., and Pirrotta V. Genome-wide analysis of Polycomb targets in Drosophila melanogaster. Nat Genet 38 (2006) 700-705
-
(2006)
Nat Genet
, vol.38
, pp. 700-705
-
-
Schwartz, Y.B.1
Kahn, T.G.2
Nix, D.A.3
Li, X.Y.4
Bourgon, R.5
Biggin, M.6
Pirrotta, V.7
-
35
-
-
33746600716
-
Histone trimethylation and the maintenance of transcriptional ON and OFF states by trxG and PcG proteins
-
Papp B., and Muller J. Histone trimethylation and the maintenance of transcriptional ON and OFF states by trxG and PcG proteins. Genes Dev 20 (2006) 2041-2054
-
(2006)
Genes Dev
, vol.20
, pp. 2041-2054
-
-
Papp, B.1
Muller, J.2
-
36
-
-
29744447772
-
Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells
-
Meshorer E., Yellajoshula D., George E., Scambler P.J., Brown D.T., and Misteli T. Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells. Dev Cell 10 (2006) 105-116
-
(2006)
Dev Cell
, vol.10
, pp. 105-116
-
-
Meshorer, E.1
Yellajoshula, D.2
George, E.3
Scambler, P.J.4
Brown, D.T.5
Misteli, T.6
-
37
-
-
26244454608
-
Distinctive nuclear organisation of centromeres and regions involved in pluripotency in human embryonic stem cells
-
Wiblin A.E., Cui W., Clark A.J., and Bickmore W.A. Distinctive nuclear organisation of centromeres and regions involved in pluripotency in human embryonic stem cells. J Cell Sci 118 (2005) 3861-3868
-
(2005)
J Cell Sci
, vol.118
, pp. 3861-3868
-
-
Wiblin, A.E.1
Cui, W.2
Clark, A.J.3
Bickmore, W.A.4
-
38
-
-
31644436473
-
Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus
-
Williams R.R., Azuara V., Perry P., Sauer S., Dvorkina M., Jorgensen H., Roix J., McQueen P., Misteli T., Merkenschlager M., et al. Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus. J Cell Sci 119 (2006) 132-140
-
(2006)
J Cell Sci
, vol.119
, pp. 132-140
-
-
Williams, R.R.1
Azuara, V.2
Perry, P.3
Sauer, S.4
Dvorkina, M.5
Jorgensen, H.6
Roix, J.7
McQueen, P.8
Misteli, T.9
Merkenschlager, M.10
-
39
-
-
20244389575
-
A dynamic switch in the replication timing of key regulator genes in embryonic stem cells upon neural induction
-
Perry P., Sauer S., Billon N., Richardson W.D., Spivakov M., Warnes G., Livesey F.J., Merkenschlager M., Fisher A.G., and Azuara V. A dynamic switch in the replication timing of key regulator genes in embryonic stem cells upon neural induction. Cell Cycle 3 (2004) 1645-1650
-
(2004)
Cell Cycle
, vol.3
, pp. 1645-1650
-
-
Perry, P.1
Sauer, S.2
Billon, N.3
Richardson, W.D.4
Spivakov, M.5
Warnes, G.6
Livesey, F.J.7
Merkenschlager, M.8
Fisher, A.G.9
Azuara, V.10
-
40
-
-
10044228269
-
Differentiation-induced replication-timing changes are restricted to AT-rich/long interspersed nuclear element (LINE)-rich isochors
-
Hiratani I., Leskovar A., and Gilbert D.M. Differentiation-induced replication-timing changes are restricted to AT-rich/long interspersed nuclear element (LINE)-rich isochors. Proc Natl Acad Sci USA 101 (2004) 16861-16866
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 16861-16866
-
-
Hiratani, I.1
Leskovar, A.2
Gilbert, D.M.3
-
41
-
-
2442695407
-
Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription
-
Chambeyron S., and Bickmore W.A. Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription. Genes Dev 18 (2004) 1119-1130
-
(2004)
Genes Dev
, vol.18
, pp. 1119-1130
-
-
Chambeyron, S.1
Bickmore, W.A.2
-
42
-
-
19744379789
-
Nuclear re-organisation of the Hoxb complex during mouse embryonic development
-
Chambeyron S., Da Silva N.R., Lawson K.A., and Bickmore W.A. Nuclear re-organisation of the Hoxb complex during mouse embryonic development. Development 132 (2005) 2215-2223
-
(2005)
Development
, vol.132
, pp. 2215-2223
-
-
Chambeyron, S.1
Da Silva, N.R.2
Lawson, K.A.3
Bickmore, W.A.4
-
43
-
-
4544255977
-
Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei
-
Zink D., Amaral M.D., Englmann A., Lang S., Clarke L.A., Rudolph C., Alt F., Luther K., Braz C., Sadoni N., et al. Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei. J Cell Biol 166 (2004) 815-825
-
(2004)
J Cell Biol
, vol.166
, pp. 815-825
-
-
Zink, D.1
Amaral, M.D.2
Englmann, A.3
Lang, S.4
Clarke, L.A.5
Rudolph, C.6
Alt, F.7
Luther, K.8
Braz, C.9
Sadoni, N.10
-
44
-
-
33646870495
-
Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
-
Bracken A.P., Dietrich N., Pasini D., Hansen K.H., and Helin K. Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev 20 (2006) 1123-1136
-
(2006)
Genes Dev
, vol.20
, pp. 1123-1136
-
-
Bracken, A.P.1
Dietrich, N.2
Pasini, D.3
Hansen, K.H.4
Helin, K.5
-
45
-
-
0037387711
-
Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 Polycomb group complexes
-
Silva J., Mak W., Zvetkova I., Appanah R., Nesterova T.B., Webster Z., Peters A.H., Jenuwein T., Otte A.P., and Brockdorff N. Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 Polycomb group complexes. Dev Cell 4 (2003) 481-495
-
(2003)
Dev Cell
, vol.4
, pp. 481-495
-
-
Silva, J.1
Mak, W.2
Zvetkova, I.3
Appanah, R.4
Nesterova, T.B.5
Webster, Z.6
Peters, A.H.7
Jenuwein, T.8
Otte, A.P.9
Brockdorff, N.10
-
46
-
-
33745549658
-
Epigenetic characterization of the early embryo with a chromatin immunoprecipitation protocol applicable to small cell populations
-
This paper describes a refined ChIP approach that can be used to analyse small numbers of cells - such as those isolated from early-stage embryos.
-
O'Neill L.P., VerMilyea M.D., and Turner B.M. Epigenetic characterization of the early embryo with a chromatin immunoprecipitation protocol applicable to small cell populations. Nat Genet 38 (2006) 835-841. This paper describes a refined ChIP approach that can be used to analyse small numbers of cells - such as those isolated from early-stage embryos.
-
(2006)
Nat Genet
, vol.38
, pp. 835-841
-
-
O'Neill, L.P.1
VerMilyea, M.D.2
Turner, B.M.3
-
47
-
-
0036733675
-
Chromatin modification and epigenetic reprogramming in mammalian development
-
Li E. Chromatin modification and epigenetic reprogramming in mammalian development. Nat Rev Genet 3 (2002) 662-673
-
(2002)
Nat Rev Genet
, vol.3
, pp. 662-673
-
-
Li, E.1
-
48
-
-
15744396813
-
The key to development: interpreting the histone code?
-
Margueron R., Trojer P., and Reinberg D. The key to development: interpreting the histone code?. Curr Opin Genet Dev 15 (2005) 163-176
-
(2005)
Curr Opin Genet Dev
, vol.15
, pp. 163-176
-
-
Margueron, R.1
Trojer, P.2
Reinberg, D.3
-
49
-
-
13844315463
-
Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation
-
Kuzmichev A., Margueron R., Vaquero A., Preissner T.S., Scher M., Kirmizis A., Ouyang X., Brockdorff N., Abate-Shen C., Farnham P., et al. Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation. Proc Natl Acad Sci USA 102 (2005) 1859-1864
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 1859-1864
-
-
Kuzmichev, A.1
Margueron, R.2
Vaquero, A.3
Preissner, T.S.4
Scher, M.5
Kirmizis, A.6
Ouyang, X.7
Brockdorff, N.8
Abate-Shen, C.9
Farnham, P.10
-
50
-
-
0030743612
-
DNA methylation and imprinting: why bother?
-
Jaenisch R. DNA methylation and imprinting: why bother?. Trends Genet 13 (1997) 323-329
-
(1997)
Trends Genet
, vol.13
, pp. 323-329
-
-
Jaenisch, R.1
-
51
-
-
0034598784
-
Demethylation of the zygotic paternal genome
-
Mayer W., Niveleau A., Walter J., Fundele R., and Haaf T. Demethylation of the zygotic paternal genome. Nature 403 (2000) 501-502
-
(2000)
Nature
, vol.403
, pp. 501-502
-
-
Mayer, W.1
Niveleau, A.2
Walter, J.3
Fundele, R.4
Haaf, T.5
-
52
-
-
0035158704
-
Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation
-
Jackson-Grusby L., Beard C., Possemato R., Tudor M., Fambrough D., Csankovszki G., Dausman J., Lee P., Wilson C., Lander E., et al. Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation. Nat Genet 27 (2001) 31-39
-
(2001)
Nat Genet
, vol.27
, pp. 31-39
-
-
Jackson-Grusby, L.1
Beard, C.2
Possemato, R.3
Tudor, M.4
Fambrough, D.5
Csankovszki, G.6
Dausman, J.7
Lee, P.8
Wilson, C.9
Lander, E.10
-
53
-
-
0029956442
-
DNA hypomethylation can activate Xist expression and silence X-linked genes
-
Panning B., and Jaenisch R. DNA hypomethylation can activate Xist expression and silence X-linked genes. Genes Dev 10 (1996) 1991-2002
-
(1996)
Genes Dev
, vol.10
, pp. 1991-2002
-
-
Panning, B.1
Jaenisch, R.2
-
54
-
-
4744372577
-
Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells
-
Jackson M., Krassowska A., Gilbert N., Chevassut T., Forrester L., Ansell J., and Ramsahoye B. Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells. Mol Cell Biol 24 (2004) 8862-8871
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8862-8871
-
-
Jackson, M.1
Krassowska, A.2
Gilbert, N.3
Chevassut, T.4
Forrester, L.5
Ansell, J.6
Ramsahoye, B.7
-
55
-
-
5444243359
-
Active genes dynamically colocalize to shared sites of ongoing transcription
-
Osborne C.S., Chakalova L., Brown K.E., Carter D., Horton A., Debrand E., Goyenechea B., Mitchell J.A., Lopes S., Reik W., et al. Active genes dynamically colocalize to shared sites of ongoing transcription. Nat Genet 36 (2004) 1065-1071
-
(2004)
Nat Genet
, vol.36
, pp. 1065-1071
-
-
Osborne, C.S.1
Chakalova, L.2
Brown, K.E.3
Carter, D.4
Horton, A.5
Debrand, E.6
Goyenechea, B.7
Mitchell, J.A.8
Lopes, S.9
Reik, W.10
-
56
-
-
33745865934
-
Chromatin in pluripotent embryonic stem cells and differentiation
-
Meshorer E., and Misteli T. Chromatin in pluripotent embryonic stem cells and differentiation. Nat Rev Mol Cell Biol 7 (2006) 540-546
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 540-546
-
-
Meshorer, E.1
Misteli, T.2
-
57
-
-
25844496592
-
The role of chromatin structure in regulating the expression of clustered genes
-
Sproul D., Gilbert N., and Bickmore W.A. The role of chromatin structure in regulating the expression of clustered genes. Nat Rev Genet 6 (2005) 775-781
-
(2005)
Nat Rev Genet
, vol.6
, pp. 775-781
-
-
Sproul, D.1
Gilbert, N.2
Bickmore, W.A.3
-
58
-
-
33745436025
-
Active chromatin hub of the mouse alpha-globin locus forms in a transcription factory of clustered housekeeping genes
-
Zhou G.L., Xin L., Song W., Di L.J., Liu G., Wu X.S., Liu D.P., and Liang C.C. Active chromatin hub of the mouse alpha-globin locus forms in a transcription factory of clustered housekeeping genes. Mol Cell Biol 26 (2006) 5096-5105
-
(2006)
Mol Cell Biol
, vol.26
, pp. 5096-5105
-
-
Zhou, G.L.1
Xin, L.2
Song, W.3
Di, L.J.4
Liu, G.5
Wu, X.S.6
Liu, D.P.7
Liang, C.C.8
-
59
-
-
0141730403
-
The beta-globin nuclear compartment in development and erythroid differentiation
-
Palstra R.J., Tolhuis B., Splinter E., Nijmeijer R., Grosveld F., and de Laat W. The beta-globin nuclear compartment in development and erythroid differentiation. Nat Genet 35 (2003) 190-194
-
(2003)
Nat Genet
, vol.35
, pp. 190-194
-
-
Palstra, R.J.1
Tolhuis, B.2
Splinter, E.3
Nijmeijer, R.4
Grosveld, F.5
de Laat, W.6
-
60
-
-
2942657608
-
Multiple interactions between regulatory regions are required to stabilize an active chromatin hub
-
Patrinos G.P., de Krom M., de Boer E., Langeveld A., Imam A.M., Strouboulis J., de Laat W., and Grosveld F.G. Multiple interactions between regulatory regions are required to stabilize an active chromatin hub. Genes Dev 18 (2004) 1495-1509
-
(2004)
Genes Dev
, vol.18
, pp. 1495-1509
-
-
Patrinos, G.P.1
de Krom, M.2
de Boer, E.3
Langeveld, A.4
Imam, A.M.5
Strouboulis, J.6
de Laat, W.7
Grosveld, F.G.8
-
61
-
-
0042880630
-
Spatial organization of gene expression: the active chromatin hub
-
de Laat W., and Grosveld F. Spatial organization of gene expression: the active chromatin hub. Chromosome Res 11 (2003) 447-459
-
(2003)
Chromosome Res
, vol.11
, pp. 447-459
-
-
de Laat, W.1
Grosveld, F.2
-
62
-
-
20444494936
-
Interchromosomal associations between alternatively expressed loci
-
Spilianakis C.G., Lalioti M.D., Town T., Lee G.R., and Flavell R.A. Interchromosomal associations between alternatively expressed loci. Nature 435 (2005) 637-645
-
(2005)
Nature
, vol.435
, pp. 637-645
-
-
Spilianakis, C.G.1
Lalioti, M.D.2
Town, T.3
Lee, G.R.4
Flavell, R.A.5
-
63
-
-
33645814398
-
CTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf1
-
Ling J.Q., Li T., Hu J.F., Vu T.H., Chen H.L., Qiu X.W., Cherry A.M., and Hoffman A.R. CTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf1. Science 312 (2006) 269-272
-
(2006)
Science
, vol.312
, pp. 269-272
-
-
Ling, J.Q.1
Li, T.2
Hu, J.F.3
Vu, T.H.4
Chen, H.L.5
Qiu, X.W.6
Cherry, A.M.7
Hoffman, A.R.8
-
64
-
-
33748259774
-
CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus
-
Splinter E., Heath H., Kooren J., Palstra R.J., Klous P., Grosveld F., Galjart N., and de Laat W. CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus. Genes Dev 20 (2006) 2349-2354
-
(2006)
Genes Dev
, vol.20
, pp. 2349-2354
-
-
Splinter, E.1
Heath, H.2
Kooren, J.3
Palstra, R.J.4
Klous, P.5
Grosveld, F.6
Galjart, N.7
de Laat, W.8
-
65
-
-
33750212321
-
Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C)
-
The authors adapt chromosome conformation capture (3C) for use with genomic microarrays (4C).
-
Simonis M., Klous P., Splinter E., Moshkin Y., Willemsen R., de Wit E., van Steensel B., and de Laat W. Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C). Nat Genet 38 (2006) 1348-1354. The authors adapt chromosome conformation capture (3C) for use with genomic microarrays (4C).
-
(2006)
Nat Genet
, vol.38
, pp. 1348-1354
-
-
Simonis, M.1
Klous, P.2
Splinter, E.3
Moshkin, Y.4
Willemsen, R.5
de Wit, E.6
van Steensel, B.7
de Laat, W.8
-
66
-
-
33750203582
-
Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions
-
Zhao Z., Tavoosidana G., Sjolinder M., Gondor A., Mariano P., Wang S., Kanduri C., Lezcano M., Sandhu K.S., Singh U., et al. Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions. Nat Genet 38 (2006) 1341-1347
-
(2006)
Nat Genet
, vol.38
, pp. 1341-1347
-
-
Zhao, Z.1
Tavoosidana, G.2
Sjolinder, M.3
Gondor, A.4
Mariano, P.5
Wang, S.6
Kanduri, C.7
Lezcano, M.8
Sandhu, K.S.9
Singh, U.10
-
67
-
-
0346220073
-
Defined conditions for neural commitment and differentiation
-
Ying Q.L., and Smith A.G. Defined conditions for neural commitment and differentiation. Methods Enzymol 365 (2003) 327-341
-
(2003)
Methods Enzymol
, vol.365
, pp. 327-341
-
-
Ying, Q.L.1
Smith, A.G.2
-
68
-
-
0030248408
-
Development of neuronal precursor cells and functional postmitotic neurons from embryonic stem cells in vitro
-
Okabe S., Forsberg-Nilsson K., Spiro A.C., Segal M., and McKay R.D. Development of neuronal precursor cells and functional postmitotic neurons from embryonic stem cells in vitro. Mech Dev 59 (1996) 89-102
-
(1996)
Mech Dev
, vol.59
, pp. 89-102
-
-
Okabe, S.1
Forsberg-Nilsson, K.2
Spiro, A.C.3
Segal, M.4
McKay, R.D.5
-
69
-
-
0037047320
-
Directed differentiation of embryonic stem cells into motor neurons
-
Wichterle H., Lieberam I., Porter J.A., and Jessell T.M. Directed differentiation of embryonic stem cells into motor neurons. Cell 110 (2002) 385-397
-
(2002)
Cell
, vol.110
, pp. 385-397
-
-
Wichterle, H.1
Lieberam, I.2
Porter, J.A.3
Jessell, T.M.4
-
70
-
-
10744229091
-
Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice
-
Barberi T., Klivenyi P., Calingasan N.Y., Lee H., Kawamata H., Loonam K., Perrier A.L., Bruses J., Rubio M.E., Topf N., et al. Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice. Nat Biotechnol 21 (2003) 1200-1207
-
(2003)
Nat Biotechnol
, vol.21
, pp. 1200-1207
-
-
Barberi, T.1
Klivenyi, P.2
Calingasan, N.Y.3
Lee, H.4
Kawamata, H.5
Loonam, K.6
Perrier, A.L.7
Bruses, J.8
Rubio, M.E.9
Topf, N.10
-
71
-
-
4344592974
-
Derivation of midbrain dopamine neurons from human embryonic stem cells
-
Perrier A.L., Tabar V., Barberi T., Rubio M.E., Bruses J., Topf N., Harrison N.L., and Studer L. Derivation of midbrain dopamine neurons from human embryonic stem cells. Proc Natl Acad Sci USA 101 (2004) 12543-12548
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 12543-12548
-
-
Perrier, A.L.1
Tabar, V.2
Barberi, T.3
Rubio, M.E.4
Bruses, J.5
Topf, N.6
Harrison, N.L.7
Studer, L.8
-
72
-
-
33748086466
-
Efficient generation of retinal progenitor cells from human embryonic stem cells
-
Lamba D.A., Karl M.O., Ware C.B., and Reh T.A. Efficient generation of retinal progenitor cells from human embryonic stem cells. Proc Natl Acad Sci USA 103 (2006) 12769-12774
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 12769-12774
-
-
Lamba, D.A.1
Karl, M.O.2
Ware, C.B.3
Reh, T.A.4
-
73
-
-
0030579185
-
Differentiation of embryonal stem cells into keratinocytes: comparison of wild-type and beta 1 integrin-deficient cells
-
Bagutti C., Wobus A.M., Fassler R., and Watt F.M. Differentiation of embryonal stem cells into keratinocytes: comparison of wild-type and beta 1 integrin-deficient cells. Dev Biol 179 (1996) 184-196
-
(1996)
Dev Biol
, vol.179
, pp. 184-196
-
-
Bagutti, C.1
Wobus, A.M.2
Fassler, R.3
Watt, F.M.4
-
74
-
-
0033578304
-
Functional characterization of B lymphocytes generated in vitro from embryonic stem cells
-
Cho S.K., Webber T.D., Carlyle J.R., Nakano T., Lewis S.M., and Zuniga-Pflucker J.C. Functional characterization of B lymphocytes generated in vitro from embryonic stem cells. Proc Natl Acad Sci USA 96 (1999) 9797-9802
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 9797-9802
-
-
Cho, S.K.1
Webber, T.D.2
Carlyle, J.R.3
Nakano, T.4
Lewis, S.M.5
Zuniga-Pflucker, J.C.6
-
75
-
-
3042627641
-
Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro
-
Schmitt T.M., de Pooter R.F., Gronski M.A., Cho S.K., Ohashi P.S., and Zuniga-Pflucker J.C. Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro. Nat Immunol 5 (2004) 410-417
-
(2004)
Nat Immunol
, vol.5
, pp. 410-417
-
-
Schmitt, T.M.1
de Pooter, R.F.2
Gronski, M.A.3
Cho, S.K.4
Ohashi, P.S.5
Zuniga-Pflucker, J.C.6
-
76
-
-
1642306055
-
VEGF-A165 augments erythropoietic development from human embryonic stem cells
-
Cerdan C., Rouleau A., and Bhatia M. VEGF-A165 augments erythropoietic development from human embryonic stem cells. Blood 103 (2004) 2504-2512
-
(2004)
Blood
, vol.103
, pp. 2504-2512
-
-
Cerdan, C.1
Rouleau, A.2
Bhatia, M.3
-
77
-
-
0027718107
-
Embryonic stem cells differentiate in vitro into cardiomyocytes representing sinusnodal, atrial and ventricular cell types
-
Maltsev V.A., Rohwedel J., Hescheler J., and Wobus A.M. Embryonic stem cells differentiate in vitro into cardiomyocytes representing sinusnodal, atrial and ventricular cell types. Mech Dev 44 (1993) 41-50
-
(1993)
Mech Dev
, vol.44
, pp. 41-50
-
-
Maltsev, V.A.1
Rohwedel, J.2
Hescheler, J.3
Wobus, A.M.4
-
78
-
-
0030016231
-
Genetically selected cardiomyocytes from differentiating embryonic stem cells form stable intracardiac grafts
-
Klug M.G., Soonpaa M.H., Koh G.Y., and Field L.J. Genetically selected cardiomyocytes from differentiating embryonic stem cells form stable intracardiac grafts. J Clin Invest 98 (1996) 216-224
-
(1996)
J Clin Invest
, vol.98
, pp. 216-224
-
-
Klug, M.G.1
Soonpaa, M.H.2
Koh, G.Y.3
Field, L.J.4
-
79
-
-
28644442419
-
Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells
-
Yasunaga M., Tada S., Torikai-Nishikawa S., Nakano Y., Okada M., Jakt L.M., Nishikawa S., Chiba T., Era T., and Nishikawa S. Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells. Nat Biotechnol 23 (2005) 1542-1550
-
(2005)
Nat Biotechnol
, vol.23
, pp. 1542-1550
-
-
Yasunaga, M.1
Tada, S.2
Torikai-Nishikawa, S.3
Nakano, Y.4
Okada, M.5
Jakt, L.M.6
Nishikawa, S.7
Chiba, T.8
Era, T.9
Nishikawa, S.10
-
80
-
-
1842426937
-
Regulation of human embryonic stem cell differentiation by BMP-2 and its antagonist noggin
-
Pera M.F., Andrade J., Houssami S., Reubinoff B., Trounson A., Stanley E.G., Ward-van Oostwaard D., and Mummery C. Regulation of human embryonic stem cell differentiation by BMP-2 and its antagonist noggin. J Cell Sci 117 (2004) 1269-1280
-
(2004)
J Cell Sci
, vol.117
, pp. 1269-1280
-
-
Pera, M.F.1
Andrade, J.2
Houssami, S.3
Reubinoff, B.4
Trounson, A.5
Stanley, E.G.6
Ward-van Oostwaard, D.7
Mummery, C.8
-
81
-
-
33750882952
-
BMP-4 is required for hepatic specification of mouse embryonic stem cell-derived definitive endoderm
-
Gouon-Evans V., Boussemart L., Gadue P., Nierhoff D., Koehler C.I., Kubo A., Shafritz D.A., and Keller G. BMP-4 is required for hepatic specification of mouse embryonic stem cell-derived definitive endoderm. Nat Biotechnol 24 (2006) 1402-1411
-
(2006)
Nat Biotechnol
, vol.24
, pp. 1402-1411
-
-
Gouon-Evans, V.1
Boussemart, L.2
Gadue, P.3
Nierhoff, D.4
Koehler, C.I.5
Kubo, A.6
Shafritz, D.A.7
Keller, G.8
-
82
-
-
33746804044
-
Derivation of distal lung epithelial progenitors from murine embryonic stem cells using a novel three-step differentiation protocol
-
Rippon H.J., Polak J.M., Qin M., and Bishop A.E. Derivation of distal lung epithelial progenitors from murine embryonic stem cells using a novel three-step differentiation protocol. Stem Cells 24 (2006) 1389-1398
-
(2006)
Stem Cells
, vol.24
, pp. 1389-1398
-
-
Rippon, H.J.1
Polak, J.M.2
Qin, M.3
Bishop, A.E.4
-
83
-
-
28644448149
-
Efficient differentiation of human embryonic stem cells to definitive endoderm
-
D'Amour K.A., Agulnick A.D., Eliazer S., Kelly O.G., Kroon E., and Baetge E.E. Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat Biotechnol 23 (2005) 1534-1541
-
(2005)
Nat Biotechnol
, vol.23
, pp. 1534-1541
-
-
D'Amour, K.A.1
Agulnick, A.D.2
Eliazer, S.3
Kelly, O.G.4
Kroon, E.5
Baetge, E.E.6
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