Morphometric and topographical studies of small neurons in sporadic amyotrophic lateral sclerosis spinal gray matter

Neuropathology

Volumn 27, Issue 2, 2007, Pages 121-126

  Hayashi, Shintaro ^a,c   Amari, Masakuni ^b   Takatama, Masamitsu ^b   Okamoto, Koichi ^a  

^a GUNMA UNIVERSITY   (Japan)

^b Geriatrics Research Institute and Hospital   (Japan)

^c GUNMA UNIVERSITY   (Japan)

Author keywords

Amyotrophic lateral sclerosis; Morphometry; Myelin; Pathology; Spinal cord

Indexed keywords

MYELIN;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CELL COUNT; CELL LOSS; CELL SIZE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GRAY MATTER; HUMAN; HUMAN TISSUE; MALE; MORPHOMETRICS; NERVE CELL; NERVE DEGENERATION; NEUROPATHOLOGY; PALLOR; PRIORITY JOURNAL; PYRAMIDAL TRACT; QUANTITATIVE ANALYSIS; SPINAL CORD; TOPOGRAPHY;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; HUMANS; MIDDLE AGED; NERVE DEGENERATION; NEURONS; SPINAL CORD;

EID: 34147183356     PISSN: 09196544     EISSN: 14401789     Source Type: Journal    
DOI: 10.1111/j.1440-1789.2007.00754.x     Document Type: Article

References (37)

1. Tsukagoshi H, Yanagisawa N, Oguchi K et al. Morphometric quantification of the cervical limb motor cells in various neuromuscular disease. J Neurol Sci 1979; 41: 287-297.
2. Oyanagi K, Makifuchi T, Ikuta F. A topographic and quantitative study in human spinal gray matter, with special reference to their changes in amyotrophic lateral sclerosis. Biomed Res 1983; 42: 211-224.
3. Oyanagi K, Ikuta F, Horikawa Y. Evidence for sequential degeneration of the intermediate zone of the spinal cord in amyotrophic lateral sclerosis: A topographic and quantitative investigation. Acta Neuropathol (Berl) 1989; 77: 343-349.
4. Swash M, Leader M, Brown A et al. Focal loss of anterior horn cells in the cervical cord in motor neuron disease. Brain 1986; 109: 939-952.
5. Mizusawa H, Hirano A, Shintaku M. Involvement of small-sized neurons in anterior horn of the spinal cord in amyotrophic lateral sclerosis. Neurol Med (Tokyo) 1987; 27: 331-336.
6. Terao S, Sobue G, Hashizume Y et al. Disease specific patterns of neuronal loss in the spinal ventral horn in amyotrophic lateral sclerosis, multiple system atrophy and X-linked recessive bulbospinal neuropathy, with special reference to the loss of small neurons in the intermediate zone. J Neurol 1994; 241: 196-203.
7. Hayashi S, Sakurai A, Amari M et al. Pathological study of the diffuse myelin pallor in the anterolateral columns of the spinal cord in amyotrophic lateral sclerosis. J Neurol Sci 2001; 188: 3-7.
8. Nathan PW, Smith MC. Fasciculi proprii of the spinal cord in man. Brain 1959; 82: 610-668.
9. Jankowska E, Lindstrom S. Morphological identification of Renshaw cells. Acta Physiol Scand 1971; 81: 428-430.
10. Kawamura Y, Peter JD. Permanent axotomy by amputation results in loss of motor neurons in man. J Neuropathol Exp Neurol 1981; 40: 658-666.
11. Stephens B, Guiloff RJ, Roberto N et al. Widespread loss of neuronal populations in the spinal ventral horn in sporadic motor neuron disease. A morphometric study. J Neurol Sci 2006; 244: 41-58.
12. Tomlinson BE, Irving D, Rebeiz IJ. Total numbers of limb motor neurons in the human lumbosacral cord and an analysis of the accuracy of various sampling procedures. J Neurol Sci 1973; 20: 313-327.
13. Kawamura Y, Peter O, Okazaki H et al. Lumbar motor neurons of man II: The number and diameter distribution of large- and intermediate diameter cytons in motor neuron columns of spinal cord of man. J Neuropathol Exp Neurol 1977; 36: 861-870.
14. Holmes G. The pathology of amyotrophic lateral sclerosis. Rev Neurol Psychiatry 1909; 7: 693-725.
15. Takahashi H, Oyanagi K, Ohama E et al. Clarke's column in sporadic amyotrophic lateral sclerosis. Acta Neuropathol (Berl) 1992; 84: 465-470.
16. Paul A, Paul C. Regular involvement of Clarke's nucleus in sporadic amyotrophic lateral sclerosis. Arch Neurol 1982; 39: 155-156.
17. Takahashi H, Oyanagi K, Ikuta F. The intermediolateral nucleus in sporadic amyotrophic lateral sclerosis. Acta Neuropathol (Berl) 1993; 86: 190-192.
18. Stephens B, Navarrete R, Guiloff RJ. Ubiquitin immunoreactivity in presumed spinal interneurons in motor neurone disease. Neuropathol Appl Neurobiol 2001; 27: 352-361.
19. Rexed B. A cytoarchitechtonic atlas of the spinal cord in the cat. J Comp Neurol 1954; 100: 297-379.
20. Oyanagi K, Kawakami E, Morita T et al. Pursuit of the origin of the large myelinated fibers of the anterolateral funiculus in the spinal cord in humans in relation to the pathomechanism in amyotrophic lateral sclerosis. Acta Neuropathol (Berl) 1999; 98: 635-640.
21. Oyanagi K, Makifuchi T, Ikuta F. The anterolateral funiculus in the spinal cord in amyotrophic lateral sclerosis. Acta Neuropathol (Berl) 1995; 90: 221-227.
22. Ikuta F, Makifuchi T, Ohama E et al. Tract degeneration of the human spinal cord: Some observation on ALS and hemispherectomized humans. Shinkei Kenkyu no Shinpo 1982; 26: 710-736.
23. Hirayama K. Some problems of clinico-pathological study of motor neuron disease. Psychiatr Neurol Jpn 1962; 64: 112-126.
24. Sharon MC, Lim RJ, Guiloff RN. Interneuronal survival and calbindin-D28K expression following motor neuron degeneration. J Neurol Sci 2000; 180: 46-51.
25. Bruijn LI, Becher MW, Lee MK et al. ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions. Neuron 1997; 18: 327-338.
26. Chiu AY, Zhai P, Dal Canto MC et al. Age-dependent penetrance of disease in a transgenic mouse model of familial amyotrophic lateral sclerosis. Mol Cell Neurosci 1995; 6: 349-362.
27. Morrison BM, Janssen WG, Jon WG et al. Time course of neuropathology in the spinal cord of G86R super-oxide dismutase transgenic mice. J Comp Neurol 1998; 391: 64-77.
28. Swash M, Fox KP. The pathology of the muscle spindle: Effect of denervation. J Neurol Sci 1974; 22: 1-24.
29. Swash M, Schwartz MS. A longitudinal study of changes in motor units in motor neuron disease. J Neurol Sci 1982; 56: 185-197.
30. Eccles JC, Eccles RM, Lundberg A. Types of neurone in and around the intermediate nucleus of the lumbosacral cord. J Physiol 1960; 154: 89-114.
31. Ellaway PH. Recurrent inhibition of fusimotor neurons exhibiting background discharge in the decerebrate and the spinal cat. J Physiol (Lond) 1971; 216: 419-439.
32. Hultborn H, Illert M, Santini M. Convergence on interneurones mediating the reciprocal Ia inhibition of motorneurones: I. Disynaptic Ia inhibition of Ia inhibitory interneurones. Acta Physiol Scand 1976; 96: 193-201.
33. Harrison PJ, Jankowska E, Zytnocki D. Lamina VIII interneurones interposed in crossed reflex pathways in the cat. J Physiol 1986; 371: 147-166.
34. Fyffe RE. Spatial distribution of recurrent inhibitory synapses on spinal motorneurones in the cat. J Neurophysiol 1991; 65: 1134-1149.
35. Brooks BR, Lewis D, Rawling J. et al. The natural history of amyotrophic lateral sclerosis. In: Williams AC (ed.). Motor Neuron Disease. London: Chapman & Hall, 1994; 131-169.
36. Jankowska E. Interneuronal relay in spinal pathways from proprioceptors. Prog Neurobiol 1992; 38: 335-378.
37. Conradi S, Ronnevi LO. Selective vulnerability of alpha motor neurons in ALS: Relation to autoantibodies to acetylcholinesterase (AchE) in ALS patients. Brain Res Bull 1993; 30: 369-371.