Macroscopic and microscopic effects of GaAlAs diode laser and dexamethasone therapies on oral mucositis induced by fluorouracil in rats

Oral Health and Preventive Dentistry

Volumn 5, Issue 1, 2007, Pages 63-71

  Lara, Renata Nemetala ^a   Guerra, Eliete Neves da Silva ^a   de Melo, Nilce Santos ^a  

^a UNIVERSITY OF BRASILIA   (Brazil)

Author keywords

Chemotherapy; Dexamethasone; Low level laser; Mucositis; Rats

Indexed keywords

ALUMINUM; ANTIINFLAMMATORY AGENT; ANTIMETABOLITE; DEXAMETHASONE; FLUOROURACIL; GALLIUM; GLUCOCORTICOID; ORGANOARSENIC DERIVATIVE;

ANIMAL; ARTICLE; BIOFILM; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DRUG EFFECT; GRANULATION TISSUE; LOW LEVEL LASER THERAPY; MALE; METHODOLOGY; MOUTH MUCOSA; MOUTH ULCER; NECROSIS; PATHOLOGY; RADIATION EXPOSURE; RANDOMIZATION; RAT; STOMATITIS; WISTAR RAT; WOUND HEALING;

ALUMINUM; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIMETABOLITES; ARSENICALS; BIOFILMS; DEXAMETHASONE; DISEASE MODELS, ANIMAL; FLUOROURACIL; GALLIUM; GLUCOCORTICOIDS; GRANULATION TISSUE; LASER THERAPY, LOW-LEVEL; MALE; MOUTH MUCOSA; NECROSIS; ORAL ULCER; RANDOM ALLOCATION; RATS; RATS, WISTAR; STOMATITIS; WOUND HEALING;

EID: 34147168545     PISSN: 16021622     EISSN: 17579996     Source Type: Journal    
DOI: 10.3290/j.ohpd.a11960     Document Type: Article

References (19)

1. Bayat M, Vasheghani MM, Razavi N, Taheri S, Rakhshan M. Effect of low-level laser therapy on the healing of second-degree burns in rats: a histological and microbiological study. J Photochem Photobiol B 2005;78:171-177.
2. Bensadoun RJ, Franquin JC, Ciais G, Darcourt V, Schubert MM, Viot M et al. Low-energy He/Ne laser in the prevention of radiation-induced mucositis. A multicenter phase III randomised study in patients with head and neck cancer. Support Care Cancer 1999;7:244-252.
3. Cornelissen AM, Maltha JC, von den HoffHW, Kuijpers-Jagtman AM. Palatal mucoperiosteal wound healing in the rat. Eur J Oral Sci 1999;107:541-547.
4. Cowen D, Tardieu C, Schubert M, Peterson D, Resbeut M, Faucher C, Franquin JC. Low energy Helium-Neon laser in the prevention of oral mucositis in patients undergoing bone marrow transplant: results of a double blind randomized trial. Int J Radiat Oncol Biol Phys 1997;38:697-703.
5. Eisen D, Lynch DP. Selecting topical and systemic agents for recurrent aphthous stomatitis. Cutis 2001;68:201-206.
6. Gabriel DA, Shea T, Olajida O, Serody JS, Comeau T. The effect of oral mucositis on morbidity and mortality in bone marrow transplant. Semin Oncol 2003;30:76-83.
7. Howarth GS, Cool JC, Bourne AJ, Ballard FJ, Read LC. Insulin-like growth factor-I (IGF-I) stimulates regrowth of the damaged intestine in rats, when administered following, but not concurrent with, methotrexate. Growth Factors 1998;15:279-292.
8. Koutná M, Janisch R, Veselská R. Effects of low-power laser irradiation on cell proliferation. Scr Med (Brno) 2003;76:163-172.
9. McBride DR. Management of aphthous ulcers. Am Fam Physician 2000;62:149-154.
10. Peterson DE, Beck SL, Keefe DM. Novel therapies. Semin Oncol Nurs 2004;20:53-58.
11. Raber-Durlacher JE. Current practices for management of oral mucositis in cancer patients. Support Care Cancer 1999;7:71-74.
12. Shirasaki H, Watanabe K, Kanaizumi E, Sato J, Konno N, Narita S, Himi T. Effect of glucocorticosteroids on tumor necrosis factor-a-induced intercellular adhesion molecule-1 expression in cultured primary human nasal epithelial cells. Clin Exp Allergy 2004;34:945-951.
13. Sonis ST. A biological approach to mucositis. J Support Oncol 2004;2:21-36.
14. Sonis ST. Mucositis as a biological process: a new hypothesis for the development of chemotherapy-induced stomatotoxicity. Oral Oncol 1998;34:39-43.
15. Sonis ST. The pathobiology of mucositis. Nat Rev Cancer 2004;4:277-284.
16. Sonis ST, Elting LS, Keefe D, Peterson DE, Schubert M, Hauer-Jensen M et al. Perspectives on cancer therapy-induced mucosal injury: pathogenesis, measurement, epidemiology, and consequences for patients. Cancer 2004;100(suppl 9):1995-2025.
17. Sonis ST, Tracey C, Shklar G, Jenson J, Florine D. An animal model for mucositis induced by cancer chemotherapy. Oral Surg Oral Med Oral Pathol 1990;69:437-443.
18. Spielberger R, StiffP, Bensinger W, Gentile T, Weisdorf D, Kewalramani T et al. Palifermin for oral mucositis after intensive therapy for hematologic cancers. N Engl J Med 2004; 351:2590-2598.
19. von Bultzingslowen I, Jontell M, Hurst P, Nannmark U, Kardos T. 5-Fluorouracil induces autophagic degeneration in rat oral keratinocytes. Oral Oncol 2001;37:537-544.