Molecular basis for substrate selectivity and specificity by an LPS biosynthetic enzyme

Biochemistry

Volumn 46, Issue 14, 2007, Pages 4294-4304

  Zou, Yaozhong ^a   Li, Chong ^a   Brunzelle, Joseph S ^b   Nair, Satish K ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b ARGONNE NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COCRYSTAL STRUCTURE; LPS BIOSYNTHETIC ENZYMES; PATHOGENESIS; SUBSTRATE SELECTIVITY;

BACTERIA; BIOSYNTHESIS; COMPLEXATION; CRYSTAL STRUCTURE; MOLECULAR DYNAMICS; POLYSACCHARIDES;

ENZYME KINETICS;

BACTERIUM LIPOPOLYSACCHARIDE; CALCIUM ION; FUCOSE; GLUCOSE; GUANOSINE DIPHOSPHATE; GUANOSINE DIPHOSPHATE MANNOSE; GUANOSINE DIPHOSPHATE MANNOSE MANNOSYL HYDROLASE; HISTIDINE; MAGNESIUM ION; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; ENTEROPATHOGENIC ESCHERICHIA COLI; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

AMINO ACID SUBSTITUTION; APOENZYMES; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GUANOSINE DIPHOSPHATE FUCOSE; GUANOSINE DIPHOSPHATE MANNOSE; GUANOSINE DIPHOSPHATE SUGARS; HOLOENZYMES; HYDROGEN BONDING; KINETICS; LEUCINE; LIPOPOLYSACCHARIDES; MODELS, CHEMICAL; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY;

NEGIBACTERIA;

EID: 34147167642     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi061056u     Document Type: Article

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