Intravenous injection of phagocytes transfected ex vivo with FGF4 DNA/ biodegradable gelatin complex promotes angiogenesis in a rat myocardial ischemia/reperfusion injury model

Basic Research in Cardiology

Volumn 102, Issue 3, 2007, Pages 209-216

  Fukuyama, Naoto ^a   Tanaka, Etsuro ^b   Tabata, Yasuhiko ^c   Fujikura, Hisanori ^a   Hagihara, Masao ^a   Sakamoto, Hiromi ^d   Ando, Kiyoshi ^a   Nakazawa, Hiroe ^a   Mori, Hidezo ^e  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOKYO UNIVERSITY OF AGRICULTURE   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^e NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Angiogenesis; Cells; Gene therapy; Growth substances; Ischemia

Indexed keywords

FIBROBLAST GROWTH FACTOR 4; GELATIN; NAKED DNA; SODIUM CHLORIDE;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIODEGRADABILITY; BLOOD FLOW; CELL ISOLATION; CONTROLLED STUDY; DRUG MECHANISM; EX VIVO STUDY; GENETIC TRANSFECTION; HEART MUSCLE ISCHEMIA; HINDLIMB; HISTOLOGY; LIMB ISCHEMIA; MACROPHAGE; MALE; MONOCYTE; NONHUMAN; NONVIRAL GENE THERAPY; PHAGOCYTE; RAT; REPERFUSION INJURY;

ANIMALS; CORONARY CIRCULATION; DISEASE MODELS, ANIMAL; FEASIBILITY STUDIES; FIBROBLAST GROWTH FACTOR 4; GELATIN; GENE THERAPY; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MICE; MYOCARDIAL REPERFUSION INJURY; NEOVASCULARIZATION, PHYSIOLOGIC; PHAGOCYTES; RATS; RATS, INBRED F344; REGIONAL BLOOD FLOW; TRANSFECTION;

EID: 34147153440     PISSN: 03008428     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00395-006-0629-9     Document Type: Article

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