CCN proteins are distinct from, and should not be considered members of, the insulin-like growth factor-binding protein superfamily [1]

Journal of Clinical Endocrinology and Metabolism

Volumn 86, Issue 2, 2001, Pages 944-945

  Grotendorst, Gary R ^a   Lau, Lester F ^b,e   Perbal, Bernard ^c,d  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ILLINOIS   (United States)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d HÔPITAL SAINT ANTOINE   (France)

^e Department of Molecular Genetics ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; CYSTEINE RICH PROTEIN 61; FIBULIN; INTEGRIN; LIGAND; NERVE GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; PROTEIN CCN; PROTEIN COP 1; PROTEIN CTGF; PROTEIN ELM 1; PROTEIN NOV; PROTEIN WISP 3; PROTIEN MAC25; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN BINDING PROTEIN 1; THROMBOSPONDIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; CELL ADHESION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; EXON; HUMAN; LETTER; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN STRUCTURE;

ULMUS;

EID: 0035097721     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.86.2.7241-1     Document Type: Letter

References (30)

1. Recommendations for nomenclature of the insulin-like growth factor binding protein superfamily
2. The modular architecture of a new family of growth regulators related to connective tissue growth factor
3. Connective tissue growth factor: A mediator of TGF-β action on fibroblasts
4. The CCN family of angiogenic regulators: The integrin connection
5. The connective tissue growth factor/cysteine-rich 61/ nephroblastoma overexpressed (CCN) family
6. Expression of cyr61, a growth factor-inducible immediate early gene
7. Connective tissue growth factor: A cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10
8. Proviral rearrangements and overexpression of a new cellular gene (nov) in myeloblastosis-associated virus type-1 induced nephroblastomas
9. Expression of the Elm1 gene, a novel gene of the CCN (connective tissue growth factor, Cyr61/cefl0, and nephroblastoma overexpressed gene) family, suppresses in vivo tumor growth and metastasis of K-1735 murine melanoma cells
10. Identification of rCOP-1, a new member of the CCN protein family, as a negative regulator for cell transformation
11. WISP genes are members of the connective tissue growth factor family that are up-regulated in Wnt-1 transformed cells and aberrantly expressed in human colon tumors
12. Cyr61, product of a growth factor-inducible immediate-early gene, promotes cell proliferation, migration, and adhesion
13. Cyr61, product of a growth factor-inducible immediate early gene, is associated with the extracellular matrix and the cell surface
14. 3
15. 3 promotes endothelial cell survival, and induces angiogenesis in vivo
16. Activation-dependent adhesion of human platelets to Cyr61 and Fisp12/mouse connective tissue growth factor is mediated through integrin IIbβ
17. The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: A clue for a role of NOVH in cell-adhesion signaling
18. CYR61, a product of a growth factor-inducible immediate early genes, promotes angiogenesis and tumor growth
19. Cyr61, product of a growth factor-inducible immediate early gene, regulates chondrogenesis in mouse limb bud mesenchymal cells
20. Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair
21. Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor
22. TGF-β induces anchorage-independent growth of NRK fibroblasts via the synergistic action of CTGF-dependent and CTGF-independent signaling pathways
23. Inhibition of TGF-β stimulated CTGF gene expression and anchorage independent growth by elevation of intracellular cAMP
24. Connective tissue growth factor mediates transforming growth factor-collagen synthesis: Down-regulation by cAMP
25. Differential expression of novH and CTGF in human glioma cell lines
26. NovH: Differential expression in developing kidney and a marker of heterotypic differentiation in Wilms' tumor
27. Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): Characterization of connective tissue growth factor as a member of the IGFBP superfamily
28. Binding properties and distribution of insulin-like growth factor binding protein-related protein 3 (IGFBP-rP3/NovH), and additional member of the IGFBP super family
29. A follistatin-like gene, mac25, may act as a growth suppressor of osteosarcoma cells