Calculated cancer risks for conventional and "potentially reduced exposure product" cigarettes

Cancer Epidemiology Biomarkers and Prevention

Volumn 16, Issue 3, 2007, Pages 584-592

  Pankow, James F ^a   Watanabe, Karen H ^a   Toccalino, Patricia L ^a   Luo, Wentai ^a   Austin, Donald F ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 BUTADIENE; 4 BIPHENYLAMINE; ACETALDEHYDE; ACRYLONITRILE; ARSENIC; BENZO[A]PYRENE; CADMIUM; CARCINOGEN; FORMALDEHYDE; LEAD; NITROSONORNICOTINE; QUINOLINE;

ARTICLE; CANCER INCIDENCE; CANCER RISK; CIGARETTE SMOKING; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; HEALTH HAZARD; HUMAN; LUNG CANCER; LUNG CARCINOGENESIS; PRIORITY JOURNAL; SMOKING HABIT;

ACETALDEHYDE; ACRYLONITRILE; BIOLOGICAL MARKERS; BUTADIENES; CARCINOGENS; HUMANS; LUNG; LUNG NEOPLASMS; RISK ASSESSMENT; SMOKING; TARS;

EID: 34147109695     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-06-0762     Document Type: Article

References (57)

1. U.S. Department of Health and Human Services. The health consequences of smoking: a report of the Surgeon General. U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health; 2004.
2. International Agency for Research on Cancer. Tobacco smoke and involuntary smoking. Lyon (France): IARC Press; 2004.
3. Djordjevic MV, Stellman SD, Zang E. Doses of nicotine and lung carcinogens delivered to cigarette smokers. J Natl Cancer Inst 2000;92:106-11.
4. Borgerding MF, Bodnar JA, Wingate DE. The 1999 Massachusetts benchmark study, final report. A research study conducted after consultation with the Massachusetts Department Public Health; 2000 July 24.
5. Gertner J. Incendiary device. New York Times Magazine 2005;154:44-51.
6. Brown and Williamson Tobacco Company. Advance Light Kings insert. 2002. Available from: http://www.fda.gov/ohrms/dockets/dailys/02/ jun02/061802/ 8004859c.pdf. Accessed 2005 Dec 20.
7. R.J. Reynolds Tobacco Co. Available from: http://www.eclipse.rjrt.com. Accessed 2005 Dec 20.
8. Hughes JR, Hecht SS, Carmella SG, Murphy SE, Callas P. Smoking behaviour and toxin exposure during six weeks use of a potential reduced exposure product: Omni. Tobacco Control 2004;13:175-9.
9. Shiftman S, Pillitteri JL, Burton SL, Di Marino ME. Smoker and ex-smoker reactions to cigarettes claiming reduced risk. Tobacco Control 2004;13:78-84.
10. Cummings KM. Tobacco risk perceptions and behavior: implications for tobacco control. Nicotine Tob Res 2004;6 Suppl 3:S285-8.
11. Burns DM, Major JM, Shanks TG, Thun MJ, Samet JM. Smoking lower yield cigarettes and disease risks. In: Shopland DR, Burns DM, Benowitz NL, Amacher RH, editors. Risks associated with smoking cigarettes with low machine-measured yields of tar and nicotine. Bethesda (MD): U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute; 2001. p. 65-158.
12. Final Opinion, United States District Court for the District of Columbia, United States of America (Plaintiff) V. Philip Morris USA, Inc. et al. (Defendants), August 17, 2006.
13. Benowitz NL. Compensatory smoking of low-yield cigarettes. In: Shopland DR, Burns DM, Benowitz NL, Amacher RH, editors. Risks associated with smoking cigarettes with low machine-measured yields of tar and nicotine. Bethesda (MD): U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute; 2001. p. 39-64.
14. Hammond D, Fong GT, Cummings KM, Hyland A. Smoking topography, brand switching, and nicotine delivery: results from an in vivo study. Cancer Epidemiol Biomarkers Prev 2005;14:1370-5.
15. Wartenberg D, Simon R. Comment: integrating epidemiologic data into risk assessment. Am J Public Health 1995;85:491-3.
16. Doll R, Peto R. Cigarette smoking and bronchial carcinoma: dose and time relationships among regular smokers and lifelong non-smokers. J Epidemiol Community Health 1978;32:303-13.
17. Villeneuve PJ, Mao Y. Lifetime probability of developing lung cancer, by smoking status, Canada. Can J Public Health 1994;85:385-8.
18. Holowaty E, Cheong SC, Di Cori S, et al. Tobacco or health in Ontario: tobacco-attributed cancers and deaths over the past 50 years ... and the next 50. Toronto (Ontario): Division of Preventive Oncology, Cancer Care Ontario; 2002.
19. Bach PB, Kattan MW, Thornquist MD, et al. Variations in lung cancer risk among smokers. J Natl Cancer Inst 2003;95:470-8.
20. U.S. Environmental Protection Agency. Risk assessment guidance for Superfund. Volume 1. Human health evaluation manual (part A), interim final. Washington (DC): Office of Emergency and Remedial Response; 1989. Report no. EPA/540/1-89/002.
21. U.S. EPA. Guidelines for the health risk assessment of chemical mixtures. Federal Register 1986;51:34014-25.
22. U.S. EPA. Guidance on cumulative risk assessment of pesticide chemicals that have a common mechanism of toxicity. Washington (DC): Office of Pesticide Programs, U.S. Environmental Protection Agency; 2002.
23. Burkart W, Jung T. Health risks from combined exposures: mechanistic considerations on deviations from additivity. Mutat Res 1998;411:119-28.
24. Preston-Martin S, Pike MC, Ross RK, Henderson BE. Epidemiologic evidence for the increased cell proliferation model of carcinogenesis. Chemically induced cell proliferation: implications for risk assessment. Wilmington (DE): Wiley-Liss; 1991. p. 21-34.
25. Zhou W, Thurston SW, Liu G, et al. The interaction between microsomal epoxide hydrolase polymorphisms and cumulative cigarette smoking in different histological subtypes of lung cancer. Cancer Epidemiol Biomarkers Prev 2001;10:461-6.
26. Thurston SW, Liu G, Miller DP, Christiani DC. Modeling lung cancer risk in case-control studies using a new dose metric of smoking. Cancer Epidemiol Biomarkers Prev 2005;14:2296-302. Erratum in: Cancer Epidemiol Biomarkers Prev 2005;14:3020.
27. Siemiatycki J. Synthesizing the lifetime history of smoking. Cancer Epidemiol Biomarkers Prev 2005;14:2294-5.
28. Vorhees DJ, Dodson RE. Estimating risk to cigarette smokers from smoke constituents in proposed "Testing and Reporting of Constituents of Cigarette Smoke" Regulations. Boston (MA): Menzie-Cura & Associates, Inc.; 1999.
29. Fowles J, Dybing E. Application of toxicological risk assessment principles to the chemical constituents of cigarette smoke. Tobacco Control 2003;12:424-30.
30. Kozlowski LT, O'Connor RJ, Sweeney CT. Cigarette design. In: Shopland DR, Burns DM, Benowitz NL, Amacher RH, editors. Risks associated with smoking cigarettes with low machine-measured yields of tar and nicotine. Bethesda (MD): U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute; 2001. p. 13-38.
31. U.S. Department of Health and Human Services. The health consequences of smoking: nicotine addiction. A report of the Surgeon General. Rockville (MD): U.S. Department of Health and Human Services Publication no. (CDC) 88-8406; 1988.
32. Lee EM, Malson JL, Moolchan ET, Pickworth WB. Quantitative comparisons between a nicotine delivery device (Eclipse) and conventional cigarette smoking. Nicotine Tob Res 2004;6:95-102.
33. Roemer E, Stabbert R, Rustemeier K, et al. Chemical composition, cytotoxicity and mutagenicity of smoke from US commercial and reference cigarettes smoked under two sets of machine smoking conditions. Toxicology 2004;195:31-52.
34. Borgerding MF, Bodnar JA, Chung HL, et al. Chemical and biological studies of a new cigarette that primarily heats tobacco. Part 1. Chemical composition of mainstream smoke. Food Chem Toxicol 1997;36:169-82.
35. Stabbert R, Voneken P, Rustemeier K, et al. Toxicological evaluation of an electrically heated cigarette. Part 2. Chemical composition of mainstream smoke. J Appl Toxicol 2003;23:329-39.
36. R.J. Reynolds Inc. Eclipse. A cigarette that primarily heats, rather than burns, tobacco. Summary of scientific tests: R. J. Reynolds Tobacco Company; 2000 April.
37. Hoffmann D, Hoffmann I. The changing cigarette: chemical studies and bioassays. In: Shopland DR, Burns DM, Benowitz NL, Amacher RH, editors. Risks associated with smoking cigarettes with low machine-measured yields of tar and nicotine. Bethesda (MD): U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute; 2001. p. 159-92.
38. Slade J, Connolly GN, Lymperis D. Eclipse: does it live up to its health claims? Tobacco Control 2002;11:64-70.
39. Byrd GD, Fowler KW, Hicks RD, Lovette ME, Borgerding MF. Isotope dilution gas chromatography-mass spectrometry in the determination of benzene, toluene, styrene and acrylonitrile in mainstream cigarette smoke. J Chromatog 1990;503:359-68.
40. Borgerding MF, Fowler KW, Rogers JC. Chemical characterization of the mainstream smoke from XDU cigarette prototype 2-104 - a summary. Feb 25, 1993. Bates no. 510259737/9765. Available from: http://legacy.library. ucsf.edu/tid/gkh63d00.
41. Anon. Mainstream smoke yields - benzene. Bates no. 510941672. Available from: http://legacy.library.ucsf.edu/tid/pty90d00.
42. Rogers JC, Fowler KW, Parsons SV, Jordan FD. Comparison of mainstream smoke from XDU (DS021492-1, 6239), Premier, and German Reference R1 cigarettes by gas chromatography with mass selective detection. Bates no. 512826632/6642. Available from: http://legacy.library.ucsf.edu/tid/ abz23d00. Accessed 2005 Feb 8. R.J. Reynolds collection; 1993.
43. Rogers JC, Winkler LS, Fowler KW. Comparison of benzene and toluene concentrations in mainstream smoke from XDU 740, Premier, and German Reference R1 cigarettes by gas chromatography with selected ion monitoring detection. Bates no. 510941680/1692. Available from: http://legacy.library.ucsf.edu/tid/ gbp53d00. Accessed 2003 Jan 22.
44. U.S. Environmental Protection Agency. Integrated Risk Information System. In: Office of Research and Development, National Center for Environmental Assessment; 2003.
45. California Environmental Protection Agency. All chronic reference exposure levels adopted by OEHHA as of August 2003. Available from: http:// www.oehha.ca.gov/air/chronic_rels/AllChrels.html. Accessed 2005 Jan 12.
46. California Environmental Protection Agency. September 2004-OEHHA cancer potency list. 2004. Available from: http://www.oehha.ca.gov/risk/ ChemicalDB/index.asp. Accessed 2005 Apr 6.
47. California Environmental Protection Agency. Expedited cancer potency values and no significant risk levels (NSRLs) for six proposition 65 carcinogens: carbazole, MeIQ, MeIQx, methyl carbamate, 4-N-nitrosome- thylamino)-1-(3-pyridyl)-1-butanone, trimethyl phosphate. Sacramento (CA): Reproductive and Cancer Hazard Assessment Section, Office of Environmental Health Hazard Assessment; 2001.
48. Surgeon General. Reducing the health consequences of smoking: 25 years of progress. Washington (DC): U.S. Gov Print Off; 1989.
49. Imperial Tobacco Ltd. Measurement of cigarette smoke components of six Imperial Tobacco cigarette brands sold in British Columbia. As cited in Vorhees and Dodson (28).
50. U.S. Environmental Protection Agency. Air Toxics Risk Assessment Reference Library Volume 1. Technical Resource Manual. Research Triangle Park (NC): Office of Air Quality Planning and Standards; 2004. Report no. EPA-453-K-04-001A.
51. Shopland DR. Tobacco use and its contribution to early cancer mortality with a special emphasis on cigarette smoking. Environ Health Perspect 1995; 103 Suppl 8:131-42.
52. GLOBOCAN 2002, Software and Database Version 2.0, September 2004. Available from: http://www-dep.iarc.fr/. Accessed 2005 Dec 20.
53. Statistics Canada. Available from: http://www40.statcan.ca/. Accessed 2005 Dec 20.
54. Gilmore J. Report on smoking in Canada. Ottawa, Ontario (Canada): Health Statistics Division, Statistics Canada Minister of Industry; 2002.
55. Canadian Council for Tobacco Control, National Clearinghouse on Tobacco and Health. Production of tobacco products. Available from: http:// www.ncth.ca/NCTH_new.nsf. Accessed 2005 Dec 20.
56. Centers for Disease Control, National Center for Chronic Disease Prevention and Health Promotion. Available from: http://www.cdc.gov/tobacco/who/ canada.htm. Accessed 2005 Dec 20.
57. National Cancer Institute. Changes in Cigarette-related disease risks and their implication for prevention, 97-4213. Bethesda (MD): U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health; 1997.