Effect of ammonia production on intracellular pH: Consequent effect on adenovirus vector production

Journal of Biotechnology

Volumn 129, Issue 3, 2007, Pages 433-438

  Ferreira, T B ^a,b   Carrondo, M J T ^a,b,c   Alves, P M ^a,b  

^a INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLÓGICA   (Portugal)

^b INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^c UNIVERSIDADE NOVA DE LISBOA   (Portugal)

Author keywords

Adenovirus; Ammonia; Cell density effect; Intracellular pH; Non ammoniagenic medium

Indexed keywords

BIOSYNTHESIS; CELL DEATH; CELL GROWTH; GENE EXPRESSION; PH EFFECTS; VIRUSES;

AMMONIAGENIC MEDIA; CELL DENSITY EFFECTS; GENE THERAPY; RECOMBINANT ADENOVIRAL VECTORS (ADV); VACCINATION;

AMMONIA;

ADENOVIRUS VECTOR; GLUTAMINE; VIRUS DNA;

ACIDITY; ADAPTATION; ADENOVIRUS; ALKALINITY; AMMONIA FORMATION; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DENSITY; CELL PH; CELL STRAIN HEK293; CELL VIABILITY; CULTURE MEDIUM; ENCAPSULATION; NONHUMAN; PRIORITY JOURNAL; REACTION ANALYSIS; REACTION TIME;

ADENOVIRIDAE; AMMONIA; BIOTECHNOLOGY; CELL COUNT; CELL CULTURE TECHNIQUES; CELL LINE; ENDODEOXYRIBONUCLEASES; FLOW CYTOMETRY; GENETIC VECTORS; HUMANS; HYDROGEN-ION CONCENTRATION; VIRUS CULTIVATION;

ADENOVIRIDAE;

EID: 34147097055     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2007.01.010     Document Type: Article

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