Role of ATP-binding cassette drug transporters in the intestinal absorption of tanshinone IIB, one of the major active diterpenoids from the root of Salvia miltiorrhiza

Xenobiotica

Volumn 37, Issue 4, 2007, Pages 375-415

  Yu, X Y ^a   Zhou, Z W ^b   Lin, S G ^a   Chen, X ^c   Yu, X Q ^c   Liang, J ^d   Duan, W ^e   Wen, J Y ^f   Li, X T ^g   Zhou, S F ^d,h  

^a GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^b NANCHANG UNIVERSITY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

^d Australian Institute of Chinese Medicine   (Australia)

^e DEAKIN UNIVERSITY   (Australia)

^f UNIVERSITY OF AUCKLAND   (New Zealand)

^g FUDAN UNIVERSITY   (China)

^h QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

Author keywords

Intestinal absorption; Multidrug resistance associated protein 1; P glycoprotein; Tanshinone IIB

Indexed keywords

2,4 DINITROPHENOL; ABC TRANSPORTER; ADENOSINE TRIPHOSPHATASE; BUTHIONINE SULFOXIMINE; CELECOXIB; DIGOXIN; DITERPENOID; ETOPOSIDE; GLYCOPROTEIN P; INDOMETACIN; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; MULTIDRUG RESISTANCE PROTEIN 5; NIFEDIPINE; PROBENECID; PROTEIN INHIBITOR; QUINIDINE; SODIUM AZIDE; SULFINPYRAZONE; TANSHINONE; VERAPAMIL; VERLUKAST; VINBLASTINE;

ARTICLE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG PENETRATION; DRUG UPTAKE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INTESTINE PERFUSION; MALE; MESENTERIC VEIN; NONHUMAN; PLANT ROOT; PLASMA CONCENTRATION-TIME CURVE; RAT; SALVIA MILTIORRHIZA; VENOUS BLOOD;

ANIMALS; ANTICOAGULANTS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; DITERPENES; HUMANS; INTESTINAL ABSORPTION; INTESTINES; MALE; MICE; MICE, KNOCKOUT; PHENANTHRENES; RATS; RATS, SPRAGUE-DAWLEY; SALVIA MILTIORRHIZA;

ANGINA; MUS; RATTUS; SALVIA MILTIORRHIZA;

EID: 34147092656     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.1080/00498250701230559     Document Type: Article

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