Effect of YM218, a nonpeptide vasopressin V1A receptor-selective antagonist, on rat mesangial cell hyperplasia and hypertrophy

Vascular Pharmacology

Volumn 46, Issue 6, 2007, Pages 463-469

  Tahara, Atsuo ^a   Tsukada, Junko ^a   Tomura, Yuichi ^a   Suzuki, Takeshi ^a   Yatsu, Takeyuki ^a   Shibasaki, Masayuki ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Mesangial cells; V1A receptors; Vasopressin receptor antagonist; YM218

Indexed keywords

ENDOTHELIN 1; ENDOTHELIN A RECEPTOR ANTAGONIST; N TERT BUTYL 4 [5' ETHOXY 4 (2 MORPHOLINOETHOXY) 2' OXOSPIRO[CYCLOHEXANE 1,3' INDOLE] 1' SULFONYL] 3 METHOXYBENZAMIDE; RELCOVAPTAN; UNCLASSIFIED DRUG; VASOPRESSIN; VASOPRESSIN 1A RECEPTOR ANTAGONIST; VASOPRESSIN RECEPTOR ANTAGONIST; YM 218; YM 598;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL GROWTH; CELL HYPERPLASIA; CONTROLLED STUDY; DNA SYNTHESIS; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG SELECTIVITY; GROWTH INHIBITION; HYPERTROPHY; MALE; MESANGIUM CELL; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN SYNTHESIS; RAT;

ANIMALS; ARGININE VASOPRESSIN; BENZAZEPINES; CELL PROLIFERATION; CELL SIZE; CELLS, CULTURED; DNA REPLICATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIN-1; HYPERPLASIA; MALE; MESANGIAL CELLS; PIPERIDINES; PROTEIN BIOSYNTHESIS; PYRIMIDINES; RATS; RATS, WISTAR; RECEPTOR, ENDOTHELIN A; RECEPTORS, VASOPRESSIN; SULFONAMIDES;

EID: 34047274950     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vph.2007.02.001     Document Type: Article

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