Synthesis, antifungal and haemolytic activity of a series of bis(pyridinium)alkanes

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 10, 2007, Pages 3422-3429

  Ng, Clarissa K L ^a   Singhal, Vatsala ^a,b   Widmer, Fred ^b   Wright, Lesley C ^b   Sorrell, Tania C ^b   Jolliffe, Katrina A ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b WESTMEAD HOSPITAL   (Australia)

Author keywords

Antifungal activity; Bispyridinium; Fungal phospholipase B1; Haemolytic activity

Indexed keywords

1,10 BIS(4 AMINOPYRIDINIUM)DECANE DIBROMIDE; 1,10 BIS(PYRIDINIUM)DECANE DIBROMIDE; 1,10 BIS(QUINOLINIUM)DECANE DIBROMIDE; 1,12 BIS(2 AMINOPYRIDINIUM)DODECANE DIBROMIDE; 1,12 BIS(4 AMINOPYRIDINIUM)DODECANE DIBROMIDE; 1,12 BIS(4 AMINOQUINALDINIUM)DODECANE DICHLORIDE; 1,12 BIS(4 N METHYLAMINOPYRIDINIUM)DODECANE DIBROMIDE; 1,12 BIS(4 N,N DIMETHYLAMINOPYRIDINIUM)DODECANE DIBROMIDE; 1,12 BIS(PYRIDINIUM)DODECANE DIBROMIDE; 1,12 BIS(QUINOLINIUM)DODECANE DICHLORIDE; 1,16 BIS(4 AMINOPYRIDINIUM)HEXADECANE DIBROMIDE; 1,6 BIS(PYRIDINIUM)HEXANE DIBROMIDE; 1,8 BIS(4 AMINOQUINALDINIUM)OCTANE DIBROMIDE; 1,8 BIS(PYRIDINIUM)OCTANE DIBROMIDE; AMPHOTERICIN B; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; DEQUALINIUM; FUNGAL ENZYME; OCTENIDINE; PHOSPHOLIPASE B1; PYRIDINIUM DERIVATIVE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; ASPERGILLUS FLAVUS; ASPERGILLUS FUMIGATUS; ASPERGILLUS TERREUS; CANDIDA ALBICANS; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; DRUG SYNTHESIS; ENZYME INHIBITION; FUSARIUM SOLANI; HEMOLYSIS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; SCEDOSPORIUM; SCEDOSPORIUM APIOSPERMUM; STATISTICAL SIGNIFICANCE;

ALKANES; AMPHOTERICIN B; ANTI-INFECTIVE AGENTS, LOCAL; ANTIBIOTICS, ANTIFUNGAL; ANTIFUNGAL AGENTS; CANDIDA ALBICANS; CRYPTOCOCCUS NEOFORMANS; DEQUALINIUM; ENZYME INHIBITORS; FUNGI; HEMOLYTIC AGENTS; HUMANS; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; MYCOSES; PHOSPHOLIPASES; PYRIDINES; PYRIDINIUM COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34047254850     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.03.018     Document Type: Article

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