The monocyte chemotactic protein-1 gene may contribute to hypertension on Dahl salt-sensitive rats

Hypertension Research

Volumn 30, Issue 2, 2007, Pages 185-193

  Yasui, Naomi ^a   Kajimoto, Kazuaki ^a   Sumiya, Toshiki ^a   Okuda, Tomohiro ^a   Iwai, Naoharu ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Candidate gene; Cc12; Ch10; Salt sensitive hypertension

Indexed keywords

ALBUMIN; MONOCYTE CHEMOTACTIC PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE MONITORING; CHROMOSOME 10; CONTROLLED STUDY; DAHL SALT SENSITIVE RAT; GENE EXPRESSION; GENE LOCATION; GENE SEQUENCE; GENETIC IDENTIFICATION; HIGH SODIUM INTAKE; HYPERTENSION; LEWIS RAT; MALE; MICROARRAY ANALYSIS; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; QUANTITATIVE TRAIT LOCUS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALT SENSITIVE HYPERTENSION; URINALYSIS; URINARY EXCRETION;

ALBUMINURIA; ANIMALS; BLOOD PRESSURE; CHEMOKINE CCL2; GENE EXPRESSION PROFILING; HYPERTENSION; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROMOTER REGIONS (GENETICS); QUANTITATIVE TRAIT LOCI; RATS; RATS, INBRED DAHL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 34047226758     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1291/hypres.30.185     Document Type: Article

References (29)

1. Garrett MR, Dene H, Walder R, et al: Genome scan and congenic strains for blood pressure QTL using Dahl salt-sensitive rats. Genome Res 1998; 8: 711-723.
2. Garrett MR, Joe B, Dene H, Rapp JP: Identification of blood pressure quantitative trait loci that differentiate two hypertensive strains. J Hypertens 2002; 20: 2399-2406.
3. Cicila GT, Rapp JP, Wang JM, St Lezin E, Ng SC, Kurtz TW: Linkage of 11 beta-hydroxylase mutations with altered steroid biosynthesis and blood pressure in the Dahl rat. Nat Genet 1993; 3: 346-353.
4. Iwai N, Yasui N, Naraba H, Tago N, Yamawaki H, Sumiya H: Klk1 as one of the genes contributing to hypertension in Dahl salt-sensitive rat. Hypertension 2005; 45: 947-953.
5. Nagai R, Nagata S: New algorithmic-based digital filter processing system for real-time continuous blood pressure measurement and analysis in conscious rats. Comput Biol Med 1995; 25: 483-494.
6. Manly KF, Cudmore RH Jr, Meer JM: Map Manager QTX, cross-platform software for genetic mapping. Mamm Genome 2001; 12: 930-932.
7. Okuda T, Sumiya T, Mizutani K, et al: Analyses of differential gene expression in genetic hypertensive rats by microarray. Hypertens Res 2002; 25: 249-255.
8. Sambrook J, Russell DW: Molecular Cloning: A Laboratory Manual, 3rd ed. Cold Spring Harbor, Cold Spring Harbor Laboratory, pp 6.4-6.12.
9. Hilgers KF, Hartner A, Porst M, et al: Monocyte chemoattractant protein-1 and macrophage infiltration in hypertensive kidney injury. Kidney Int 2000; 58: 2408-2419.
10. Chow FY, Nikolic-Paterson DJ, Ozols E, Atkins RC, Rollin BJ, Tesch GH: Monocyte chemoattractant protein-1 promotes the development of diabetic renal injury in streptozotocin-treated mice. Kidney Int 2006; 69: 73-80.
11. Furuichi K, Wada T, Iwata Y, et al: CCR2 signaling contributes to ischemia-reperfusion injury in kidney. J Am Soc Nephrol 2003; 14: 2503-2515.
12. Vieira JM Jr, Rodrigues LT, Mantovani E, et al: Statin monotherapy attenuates renal injury in a salt-sensitive hypertension model of renal disease. Nephron Physiol 2005; 101: 82-91.
13. Kikuchi Y, Imakiire T, Yamada M, et al: Mizoribine reduces renal injury and macrophage infiltration in non-insulin-dependent diabetic rats. Nephrol Dial Transplant 2005; 20: 1573-1581.
14. Aoyama I, Shimokata K, Niwa T: An oral adsorbent down-regulates renal expression of genes that promote interstitial inflammation and fibrosis in diabetic rats. Nephron 2002; 92: 635-651.
15. Hermann M, Shaw S, Kiss E, et al: Selective COX-2 inhibitors and renal injury in salt-sensitive hypertension. Hypertension 2005; 45: 193-197.
16. Johnson RJ, Herrera-Acosta J, Schreiner GF, Rodriguez-Iturbe B: Subtle acquired renal injury as a mechanism of salt-sensitive hypertension. N Engl J Med 2002; 346: 913-923.
17. Kumai Y, Ooboshi H, Takada J, et al: Anti-monocyte chemoattractant protein-1 gene therapy protects against focal brain ischemia in hypertensive rats. J Cereb Blood Flow Metab 2004; 24: 1359-1368.
18. Shimizu H, Maruyama S, Yuzawa Y, et al: Anti-monocyte chemoattractant protein-1 gene therapy attenuates renal injury induced by protein-overload proteinuria. J Am Soc Nephrol 2003; 14: 1496-1505.
19. Wada T, Furuichi K, Sakai N, et al: Gene therapy via blockade of monocyte chemoattractant protein-1 for renal fibrosis. J Am Soc Nephrol 2004; 15: 940-948.
20. Shimizu S, Nakashima H, Masutani K, et al: Anti-monocyte chemoattractant protein-1 gene therapy attenuates nephritis in MRL/lpr mice. Rheumatology 2004; 43: 1121-1128.
21. Tesch GH, Schwarting A, Kinoshita K, Lan HY, Rollins BJ, Kelley VR: Monocyte chemoattractant protein-1 promotes macrophage-mediated tubular injury, but not glomerular injury, in nephrotoxic serum nephritis. J Clin Invest 1999; 103: 73-80.
22. Deng AY, Rapp JP: Locus for the inducible, but not a constitutive, nitric oxide synthase cosegregates with blood pressure in the Dahl salt-sensitive rat. J Clin Invest 1995; 95: 2170-2177.
23. Sivo Z, Malo B, Dutil J, Deng AY: Accelerated congenics for mapping two blood pressure quantitative trait loci on chromosome 10 of Dahl rats. J Hypertens 2002; 20: 45-53.
24. Palijan A, Lambert R, Dutil J, Sivo Z, Deng AY: Comprehensive congenic coverage revealing multiple blood pressure quantitative trait loci on Dahl rat chromosome 10. Hypertension 2003; 42: 515-522.
25. Charron S, Duong C, Menard A, et al: Epistasis, not numbers, regulates functions of clustered Dahl rat quantitative trait loci applicable to human hypertension. Hypertension 2005; 46: 1300-1308.
26. Ishizawa K, Yoshizumi M, Tsuchiya K, et al: Dual effects of endothelin-1 (1-31): induction of mesangial cell migration and facilitation of monocyte recruitment through monocyte chemoattractant protein-1 production by mesangial cells. Hypertens Res 2005; 27: 433-440.
27. Naraba H, Iwai N: Assessment of the microRNA system in salt-sensitive hypertension. Hypertens Res 2005; 28; 819-826.
28. Katayama S, Tomaru Y, Kasukawa T, et al: Antisense transcription in the mammalian transcriptome. Science 2005; 309: 1564-1566.
29. Caminci P, Kasukawa T, Katayama S, et al: The transcriptional landscape of the mammalian genome. Science 2005; 309: 1559-1563.