Role of Gts1p in regulation of energy-metabolism oscillation in continuous cultures of the yeast Saccharomyces cerevisiae

Yeast

Volumn 24, Issue 3, 2007, Pages 161-170

  Xu, Zhaojun ^a   Tsurugi, Kunio ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

Continuous culture; Energy metabolism oscillation; GTS1; Storage carbohydrates

Indexed keywords

ALCOHOL; FUNGAL PROTEIN; GLYCOGEN; GTS 1P PROTEIN; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; TREHALOSE; UNCLASSIFIED DRUG;

AREA UNDER THE CURVE; ARTICLE; CARBOHYDRATE SYNTHESIS; CELL POPULATION; CONTINUOUS CULTURE; ENERGY METABOLISM; ENZYME REGULATION; FEEDBACK SYSTEM; FUNGUS CULTURE; GENE DELETION; GLYCOLYSIS; METABOLIC INHIBITION; NONHUMAN; OSCILLATION; OXIDATION REDUCTION REACTION; OXIDATION REDUCTION STATE; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STABILITY; SACCHAROMYCES CEREVISIAE;

AEROBIOSIS; BIOLOGICAL CLOCKS; CARBOHYDRATE METABOLISM; ENERGY METABOLISM; ETHANOL; GENE DELETION; GLYCOGEN; GLYCOLYSIS; GLYCOSYLTRANSFERASES; NAD; OXYGEN; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION FACTORS; TREHALOSE;

SACCHAROMYCES CEREVISIAE;

EID: 34047224016     PISSN: 0749503X     EISSN: 10970061     Source Type: Journal    
DOI: 10.1002/yea.1468     Document Type: Article

References (35)

1. Albina JE, Mastrofrancesco B, Reichner JS. 1999. Acyl phosphatase activity of NO-inhibited glyceraldehyde-3-phosphate dehydrogenase (GAPDH): a potential mechanism for uncoupling glycolysis from ATP generation in NO-producing cells. Biochem J 341: 5-9.
2. Aon MA, Cortassa S, Westerhoff HV, van Dam K. 1992. Synchrony and mutual stimulation of yeast cells during fast glycolytic oscillations. J Gen Microbiol 138: 2219-2227.
3. Arutyunov DY, Muronetz VI. 2003. The activation of glycolysis performed by the nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase in the model system. Biochem Biophys Res Commun 300: 149-154.
4. Farkas I, Hardy TA, Goebl MG, Roach PJ. 1991. Two glycogen synthase isoforms in Saccharomyces cerevisiae are coded by distinct genes that are differentially controlled. J Biol Chem 266: 15602-15607.
5. Fiske CH, Subbarow Y. 1925. The colorimetric determination of phosphorus. J Biol Chem 66: 375-400.
6. Gonzalez MI, Stucka R, Blazquez MA, Feldmann H, Gancedo C. 1992. Molecular cloning of CIF1, a yeast gene necessary for growth on glucose. Yeast 8: 183-192.
7. Hwang PK, Tugendreich S, Fletterick RJ. 1989. Molecular analysis of GPH1, the gene encoding glycogen phosphorylase in Saccharomyces cerevisiae. Mol Cell Biol 9: 1659-1666.
8. Ito T, Chiba T, Ozawa R, et al. 2001. A comprehensive two-hybrid analysis to explore the yeast protein interactome. Proc Natl Acad Sci USA 98: 4569-4574.
9. Jules M, Francois J, Parrou JL. 2005. Autonomous oscillations in Saccharomyces cerevisiae during batch cultures on trehalose. FEBS J 272: 1490-1500.
10. King DP, Zhao Y, Sangoram AM, et al. 1997. Positional cloning of the mouse circadian clock gene. Cell 89: 641-653.
11. Martegani E, Porro D, Ranzi BM, Alberghina L. 1990. Involvement of a cell size control mechanism in the induction and maintenance of oscillations in continuous cultures of budding yeast. Biotech Bioeng 36: 453-459.
12. Mitsui K, Yaguchi S, Tsurugi K. 1994. The GTS1 gene, which contains a Gly-Thr repeat, affects the timing of budding and cell size of the yeast Saccharomyces cerevisiae. Mol Cell Biol 14: 5569-5578.
13. Murray DB, Klevecz RR, Lloyd D. 2003. Generation and maintenance of synchrony in Saccharomyces cerevisiae continuous culture. Exp Cell Res 287: 10-15.
14. Parrou JL, Teste MA, Francois J. 1997. Effects of various types of stress on the metabolism of reserve carbohydrates in Saccharomyces cerevisiae: genetic evidence for a stress-induced recycling of glycogen and trehalose. Microbiology 143: 1891-1900.
15. Parulekar SJ, Semones GB, Rolf M, Lievense JC, Lim HC. 1986. Induction and elimination of oscillations in continuous cultures of Saccharomyces cerevisiae. Biotechnol Bioeng 28: 700-710.
16. Porro D, Martegani E, Ranzi BM, Alberghina L. 1988. Oscillations in continuous cultures of budding yeast: a segregated parameter analysis. Biotechnol Bioeng 32: 411-417.
17. Postma E, Verduyn C, Scheffers WA, van Dijken JP. 1989. Enzymic analysis of the Crabtree effect in glucose-limited chemostat cultures of Saccharomyces cerevisiae. Appl Environ Microbiol 55: 468-477.
18. Richard P, Bakker BM, Teusink B, Van Dam K, Westerhoff HV. 1996. Acetaldehyde mediates the synchronization of sustained glycolytic oscillations in populations of yeast cells. Eur J Biochem 235: 238-241.
19. Richard P. 2003. The rhythm of yeast. FEMS Microbiol Rev 27: 547-557.
20. Saleem Q, Anand A, Jain S, Brahmachari SK. 2001. The polyglutamine motif is highly conserved at the Clock locus in various organisms and is not polymorphic in humans. Hum Genet 109: 136-142.
21. Schmalhausen EV, Nagradova NK, Boschi-Muller S, Branlant G, Muronetz VI. 1999. Mildly oxidized GAPDH: the coupling of the dehydrogenase and acyl phosphatase activities. FEBS Lett 452: 219-222.
22. Taguchi H, Humphrey AE. 1966. Dynamic measurement of the volmetric oxygen transfer coefficient in fermentation systems. Ferment Technol 44: 881-889.
23. Thevelein JM, Hohmann S. 1995. Trehalose synthase: guard to the gate of glycolysis in yeast? Trends Biol Sci 20: 3-10.
24. Tonozuka H, Wang J, Mitsui K, et al. 2001. Analysis of the upstream regulatory region of the GTS1 gene required for its oscillatory expression. J Biochem 130: 589-595.
25. Uetz P, Giot L, Cagney G, et al. 2000. A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 403: 623-627.
26. Uno T, Wang J, Mitsui K, et al. 2002. Ultradian rhythm of trehalose levels coupled to heat resistance in continuous cultures of the yeast Saccharomyces cerevisiae. Chronobiol Int 19: 361-375.
27. Wang J, Liu W, Mitsui K, Tsurugi K. 2001. Evidence of the involvement of the GTS1 gene product in the regulation of biological rhythms in the continuous culture of the yeast Saccharomyces cerevisiae. FEBS Lett 489: 81-86.
28. Wang J, Liu W, Uno T, et al. 2000. Cellular stress responses oscillate in synchronization with the ultradian oscillation of energy metabolism in the yeast Saccharomyces cerevisiae. FEMS Microbiol Lett 189: 9-13.
29. Wang J, Mitsui K, Tsurugi K. 1998. The GTS1 gene product influences the ultradian oscillation of glycolysis in cell suspension of the yeast Saccharomyces cerevisiae. Biochem Biophys Res Commun 244: 239-242.
30. Xiao H, Jeang KT. 1998. Glutamine-rich domains activate transcription in yeast Saccharomyces cerevisiae. J Biol Chem 273: 22873-22876.
31. Xu Z, Tsurugi K. 2006. A potential mechanism of energy-metabolism oscillation in an aerobic chemostat culture of the yeast Saccharomyces cerevisiae. FEBS J 273: 1696-1709.
32. Xu Z, Yaguchi S, Tsurugi K. 2004. Gts1p stabilizes oscillations in energy metabolism by activating the transcription of TPS1 encoding trehalose-6-phosphate synthase 1 in the yeast Saccharomyces cerevisiae. Biochem J 383: 171-178.
33. Yaguchi S, Mitsui K, Kawabata K, Xu Z, Tsurugi K. 1996. The pleiotropic effect of the GTS1 gene product on heat tolerance, sporulation and the life span of Saccharomyces cerevisiae. Biochem Biophys Res Commun 218: 234-237.
34. Yaguchi S, Mitsui K, Tsurugi K. 1997. Reexamination of the nucleotide sequence of GTS1, a candidate clock-related gene of Saccharomyces cerevisiae. Biochem Arch 13: 97-105.
35. Yaguchi S, Tsurugi K. 2003. Gts1p activates SNF1-dependent derepression of HSP104 and TPS1 in the stationary phase of yeast growth. J Biol Chem 278: 29760-29768.