Carry-over of Fusarium toxins (deoxynivalenol and zearalenone) from naturally contaminated wheat to pigs

Food Additives and Contaminants

Volumn 24, Issue 4, 2007, Pages 369-380

  Goyarts, Tanja ^a   Dänicke, Sven ^a   Valenta, Hana ^a   Ueberschär, Karl Heinz ^a  

^a INSTITUTE FOR EPIDEMIOLOGY AND PATHOGEN DIAGNOSTICS   (Germany)

Author keywords

Carry over; Deoxynivalenol; Fusarium; Pigs; Zearalenone

Indexed keywords

VOMITOXIN; ZEARALENONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILE LEVEL; BLOOD LEVEL; BODY FAT; BODY FLUID; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIETARY INTAKE; ENVIRONMENTAL EXPOSURE; FEMALE; FOOD CONTAMINATION; FUSARIUM; KIDNEY PARENCHYMA; LIVER LEVEL; MALE; METABOLITE; MUSCLE LEVEL; NONHUMAN; PRIORITY JOURNAL; RELIABILITY; RISK ASSESSMENT; SWINE; TIME; TISSUE LEVEL; WHEAT;

ADIPOSE TISSUE; ANIMAL FEED; ANIMALS; BILE; FEMALE; FOOD CONTAMINATION; FUSARIUM; KIDNEY; LIVER; MALE; MUSCLES; SWINE; TRICHOTHECENES; TRITICUM; ZEARALENONE;

ANIMALIA; FUSARIUM; SUIDAE; TRITICUM AESTIVUM;

EID: 34047217147     PISSN: 0265203X     EISSN: 14645122     Source Type: Journal    
DOI: 10.1080/02652030600988038     Document Type: Article

References (25)

1. Biehl, ML, Prelusky, DB, Koritz, GD, Hartin, KE, Buck, WB and Trenholm, HL (1993) Biliary excretion and enterohepatic cycling of zearalenone in immature pigs. Toxicology and Applied Pharmacology, 121, pp. 152-159.
2. Dänicke, S., Brüssow, KP, Goyarts, T., Valenta, H., Ueberschar, KH and Tiemann, U. (2006) Food and Chemical Toxicology. On the transfer of the Fusarium toxins deoxynivalenol (DON) and zearalenone (ZON) from the sow to the piglet during the last third of gestation
3. Dänicke, S., Brüssow, KP, Valenta, H., Ueberschar, KH, Tiemann, U. and Schollenberger, M. (2005) On the effects of graded levels of Fusarium toxin contaminated wheat in diets for gilts on feed intake, growth performance and metabolism of deoxynivalenol and zearalenone. Molecular Nutrition Food Research, 49, pp. 932-943.
4. Dänicke, S., Swiech, E., Buraczewska, L. and Ueberschär, KH (2005) Kinetics and metabolism of zearalenone in young female pigs. Journal of Animal Physiology and Animal Nutrition, 89, pp. 268-276.
5. Dänicke, S., Goyarts, T., Valenta, H., Razzazi, E. and Böhm, J. (2004) On the effects of increasing deoxynivalenol (DON) concentrations in pig feed on growth performance, utilization of nutrients and metabolism of DON. Journal of Animal and Feed Sciences, 13, pp. 539-556.
6. Dänicke, S., Ueberschär, KH, Halle, I., Valenta, H. and Flachowsky, G. (2001) Excretion kinetics and metabolism of zearalenone in broilers in dependence on a detoxifying agent. Archive of Animal Nutrition, 55, pp. 299-313.
7. Döll, S., Gericke, S., Dänicke, S., Raila, J., Ueberschär, KH, Valenta, H., Schnurrbusch, U., Schweigert, FJ and Flachowsky, G. (2005) The efficacy of a modified aluminosilicate as a detoxifying agent in Fusarium-toxin contaminated maize containing diets for piglets. Journal of Animal Physiology and Animal Nutrition, 89, pp. 342-358.
8. Döll, S., Dänicke, S., Ueberschär, KH, Valenta, H., Schnurrbusch, U., Ganter, M., Klobasa, F. and Flachowsky, G. (2003) Effects of graded levels of Fusarium toxin-contaminated maize in diets for female weaned piglets. Archives of Animal Nutrition, 57, pp. 311-334.
9. EFSA (2004) Opinion of the Scientific Panel on Contaminants in the Food Chain on a request from the Commission related to deoxynivalenol (DON) as undesirable substance in animal feed. The EFSA Journal, 73, pp. 1-41.
10. EFSA (2004) Opinion of the Scientific Panel on Contaminants in the Food Chain on a request from the Commission related to zearalenone as undesirable substance in animal feed. The EFSA Journal, 89, pp. 1-35.
11. Eriksen, GS, Pettersson, H. and Lindberg, JE (2003) Absorption, metabolism and excretion of 3-acetyl DON in pigs. Archives of Animal Nutrition, 57, pp. 335-345.
12. GfE (1987) Energie- und Nährstoffbedarf landwirtschaftlicher Nutztiere, Nr. 4 Schweine, DLG Verlag, Frankfurt (Main)
13. Goyarts, T. and Dänicke, S. (2006) Bioavailability of the Fusarium toxin deoxynivalenol (DON) from naturally contaminated wheat for the pig. Toxicology Letters, 163, pp. 171-182.
14. Goyarts, T., Dänicke, S., Rothkötter, HJ, Spilke, J., Tiemann, U. and Schollenberger, M. (2005) On the effects of a chronic deoxynivalenol (DON) intoxication on performance, haematological and serum parameters of pigs when diets are offered either for ad libitum consumption or fed restrictively. Journal of Veterinary Medicine A, 52, pp. 305-314.
15. Naumann, C. and Bassler, R. (1997) Die chemische Untersuchung von Futtermitteln, VDLUFA Verlag, Darmstadt
16. Pestka, JJ and Smolinski, AT (2005) Deoxynivalenol: Toxicology and potential effects on humans. Journal of Toxicology and Environmental Health-Part B Critical Reviews, 8, pp. 39-69.
17. Prelusky, DB and Trenholm, HL (1991) Tissue distribution of deoxynivaleol in swine dosed intravenously. Journal of Agricultural and Food Chemistry, 39, pp. 748-751.
18. Prelusky, DB and Trenholm, HL (1992) Nonaccumulation of residues in swine tissue following extended consumption of deoxynivalenol-contaminated diets. Journal of Food Science, 57, pp. 801-802.
19. Prelusky, DB, Hartin, KE, Trenholm, HL and Miller, JD (1988) Pharmacokinetic fate of 14C-labeled deoxynivalenol in swine. Fundamental and Applied Toxicology, 10, pp. 276-286.
20. Rotter, BA, Prelusky, DB and Pestka, JJ (1996) Toxicology of deoxynivalenol (vomitoxin). Journal of Toxicology and Environmental Health, 48, pp. 1-34.
21. Schneeweis, I., Meyer, K., Ritzmann, M., Hoffmann, P., Dempfle, L. and Bauer, J. (2005) Influence of organically or conventionally produced wheat on health, performance and mycotoxin residues in tissues and bile of growing pigs. Archives of Animal Nutrition, 59, pp. 155-163.
22. Schollenberger, M., Lauber, U., Jara, H Terry, Suchy, S., Drochner, W. and Müller, H-M (1998) Determination of eight trichothecenes by gas chromatography-mass spectrometry after sample clean-up by a two-stage solid-phase extraction. Journal of Chromatography, 815, pp. 123-132.
23. Ueberschär, K-H (1999) Einfluß von Zearalenon auf Wachstum und Rückstände in den Geweben von Mastkaninchen. VDLUFA-Kongreßband 1999, Halle/Saale, VDLUFA-Schriftenreihe, 521999, pp. 425-428.
24. Valenta, H., Dänicke, S. and Wolff, J. (2002) Vergleich einer HPLC- und einer ELISA- Methode zur Bestimmung von Deoxynivalenol in Mühlenstäuben, Kleien und Getreide. VDLUFA-Kongreßband 2002, Leipzig: VDLUFA Schriftreihe, 582003, pp. 675-679.
25. Valenta, H., Dänicke, S. and Döll, S. (2003) Analysis of deoxynivalenol and de-epoxy-deoxynivalenol in animal tissues by liquid chromatography after clean-up with an immunoaffinity column. Mycotoxin Research, 19, pp. 51-55.