Differential regulation of membrane associated-growth hormone binding protein (MA-GHBP) and growth hormone receptor (GHR) expression by growth hormone (GH) in mouse liver

Growth Hormone and IGF Research

Volumn 17, Issue 2, 2007, Pages 104-112

  Gonzalez L ^a   Curto, L M ^a   Miquet, J G ^a   Bartke, A ^b   Turyn, D ^a   Sotelo, A I ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b Section of Colorectal Surgery   (United States)

Author keywords

GH receptor (GHR); GH regulation; GH binding protein (GHBP); Growth hormone (GH); Membrane associated GHBP

Indexed keywords

GROWTH HORMONE; GROWTH HORMONE BINDING PROTEIN; GROWTH HORMONE RECEPTOR; MESSENGER RNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL FRACTIONATION; CELL MEMBRANE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; FEMALE; GENE INSERTION; GROWTH HORMONE DEFICIENCY; HORMONE ACTION; HORMONE BINDING; LIVER MICROSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; RABBIT; RADIOIMMUNOASSAY; RECEPTOR BINDING; RNA PROCESSING; RODENT; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; UPREGULATION; WESTERN BLOTTING;

ANIMALS; CARRIER PROTEINS; CATTLE; CELL MEMBRANE; FEMALE; GROWTH HORMONE; LIVER; MICE; MICE, TRANSGENIC; RECEPTORS, SOMATOTROPIN; UP-REGULATION;

EID: 34047167898     PISSN: 10966374     EISSN: 15322238     Source Type: Journal    
DOI: 10.1016/j.ghir.2006.12.002     Document Type: Article

References (53)

1. Ross R.J., Leung K.C., Maamra M., Bennett W., Doyle N., Waters M.J., and Ho K.K. Binding and functional studies with the growth hormone receptor antagonist, B2036-PEG (pegvisomant), reveal effects of pegylation and evidence that it binds to a receptor dimmer. J. Clin. Endocrinol. Metab. 86 (2001) 1716-1723
2. Gent J., van Kerkhof P., Roza M., Bu G., and Strous G.J. Ligand-independent growth hormone receptor dimerization occurs in the endoplasmic reticulum and is required for ubiquitin system-dependent endocytosis. Proc. Natl. Acad. Sci. USA 99 (2002) 9858-9863
3. Brown R.J., Adams J.J., Pelekanos R.A., et al. Model for growth hormone receptor activation based on subunit rotation within a receptor dimmer. Nat. Struct. Mol. Biol. 12 (2005) 814-821
4. Waters M.J., Hoang H.N., Fairlie D.P., Pelekanos R.A., and Brown R.J. New insights into growth hormone action. J. Mol. Endocrinol. 36 (2006) 1-7
5. Bernat S., Pal G., Sun M., and Kossiakoff A.A. Determination of the energetics governing the regulatory step in growth hormone-induced receptor homodimerization. Proc. Natl. Acad. Sci. USA 100 (2003) 952-957
6. Waxman D.J., and Frank S.J. Growth hormone action. In: Conn P.M., and Means A.R. (Eds). Principles of Molecular Regulation (2000), Humana Press Inc., Totowa, NJ 55-83
7. Herrington J., and Carter-Su C. Signaling pathways activated by the growth hormone receptor. Trends Endocrinol. Metab. 12 (2001) 252-257
8. Heaney M.L., and Golde D.W. Soluble hormone receptors. Blood 82 (1993) 2088-2095
9. Rose-John S., and Heinrich P.C. Soluble receptors for cytokines and growth factors: generation and biological function. Biochem. J. 300 (1994) 281-290
10. Baumann G. Growth hormone binding protein. J. Pediatr. Endocrinol. & Metab. 14 (2001) 355-375
11. Fisker S. Physiology and pathophysiology of growth hormone-binding protein: methodological and clinical aspects. Growth Horm. IGF Res. 16 (2006) 1-28
12. Hansen T.K., Fisker S., Hansen B., Sorensen H.H., Christiansen J.S., Jorgensen J.O., and Orskov H. Impact of GHBP interference on estimates of GH and GH pharmacokinetics. Clin. Endocrinol. (Oxford) 57 (2002) 779-786
13. Baumann G., and Frank S.J. Metalloproteinases and the modulation of GH signaling. J. Endocrinol. 174 (2002) 361-364
14. Zhang Y., Jiang J., Black R.A., Baumann G., and Frank S.J. Tumor necrosis factor-alpha converting enzyme (TACE) is a growth hormone binding protein (GHBP) sheddase: the metalloprotease TACE/ADAM-17 is critical for (PMA-induced) GH receptor proteolysis and GHBP generation. Endocrinology 141 (2000) 4342-4348
15. Wang X., He K., Gerhart M., Huang Y., Jiang J., Paxton R.J., Yang S., Lu C., Menon R.K., Black R.A., Baumann G., and Frank S.J. Metalloprotease-mediated GH receptor proteolysis and GHBP shedding. Determination of extracellular domain stem region cleavage site. J. Biol. Chem. 277 (2002) 50510-50519
16. Schantl J.A., Roza M., van Kerkhof P., and Strous G.J. The growth hormone receptor interacts with its sheddase, the tumor necrosis factor-alpha-converting enzyme (TACE). Biochem. J. 377 (2004) 379-384
17. Ross R.J., Esposito N., Shen X.Y., Von Laue S., Chew S.L., Dobson P.R., Postel Vinay M.C., and Finidori J. A short isoform of the human growth hormone receptor functions as a dominant negative inhibitor of the full-length receptor and generates large amounts of binding protein. Mol. Endocrinol. 11 (1997) 265-273
18. Dastot F., Sobrier M.L., Duquesnoy P., Duriez B., Goossens M., and Amselem S. Alternatively spliced forms in the cytoplasmic domain of the human growth hormone (GH) receptor regulate its ability to generate a soluble GH-binding protein. Proc. Natl. Acad. Sci. USA 93 (1996) 10723-10728
19. Dastot F., Duquesnoy P., Sobrier M.L., Goossens M., and Amselem S. Evolutionary divergence of the truncated growth hormone receptor isoform in its ability to generate a soluble growth hormone binding protein. Mol. Cell. Endocrinol. 137 (1998) 79-84
20. Iida K., Takahashi Y., Kaji H., et al. Diverse regulation of full-length and truncated growth hormone receptor expression in 3T3-L1 adipocytes. Mol. Cell. Endocrinol. 210 (2003) 21-29
21. Leung D.W., Spencer S.A., Cachianes G., et al. Growth hormone receptor and serum binding protein: purification, cloning and expression. Nature 330 (1987) 537-543
22. Frick G.P., and Goodman H.M. Characterization of the short isoform of the growth hormone receptor synthesized by rat adipocytes. Endocrinology 131 (1992) 3083-3090
23. Frick G.P., Tai L.R., and Goodman H.M. Subcellular distribution of the long and short isoforms of the GH receptor in rat adipocytes. Endocrinology 134 (1994) 307-314
24. Camarillo I.G., Thordarson G., Ilkbahar Y.N., and Talamantes F. Development of a homologous radioimmunoassay for mouse growth hormone receptor. Endocrinology 139 (1998) 3585-3589
25. González L., Sotelo A.I., Bartke A., and Turyn D. Growth hormone (GH) and 17β-estradiol regulation of membrane-associated GH binding protein and GH receptors. GH & IGF-1 Res. 11 (2001) 34-40
26. Cerio R.J., Xing F., Fatula R.J., Keith D.E., Yang X., Talamantes F., and Southard J.N. Structurally distinct membrane-associated and soluble forms of GH-binding protein in the mouse. J. Endocrinol. 172 (2002) 321-331
27. Iida K., Takahashi Y., Kaji H., et al. Functional characterization of truncated growth hormone (GH) receptor-(1-277) causing partial GH insensitivity syndrome with high GH-binding protein. J. Clin. Endocrinol. Metab. 84 (1999) 1011-1016
28. Perrot-Applanat M., Gualillo O., Pezet A., Vincent V., Edery M., and Kelly P.A. Dominant negative and cooperative effects of mutant forms of prolactin receptor. Mol. Endocrinol. 11 (1997) 1020-1032
29. Bartke A. Histology of the anterior hypophysis, thyroid and gonads of two types of dwarf mice. Anatom. Rec. 149 (1964) 225-236
30. Sornson M.W., Wu W., Dasen J.S., Flynn S.E., Norman D.J., O'Connell S.M., Gukovsky I., Carriere C., Ryan A.K., Miller A.P., Zuo L., Gleiberman A.S., Andersen B., Beamer W.G., and Rosenfeld M.G. Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism. Nature 384 (1996) 327-333
31. Wagner T.E., Hoppe P.C., Jollick J.D., Scholl D.R., Hodinka R.L., and Gault J.B. Microinjection of a rabbit beta-globin gene into zygotes and its subsequent expression in adult mice and their offspring. Proc. Natl. Acad. Sci. USA 78 (1981) 6376-6380
32. McGrane M.M., de Vente J., Yun J.S., Bloom J., Park E., Wynshaw A., Wagner T.E., Rottman F.M., and Hanson R.W. Tissue specific expression and dietary regulation of chimeric phosphoenolpiruvate carboxykinase/bovine growth hormone gene in transgenic mice. J. Biol. Chem. 263 (1988) 11443-11451
33. Milton S., Cecim M., Li Y.S., Yun J.S., Wagner T.E., and Bartke A. Transgenic female mice with high human growth hormone levels are fertile and capable of normal lactation without having been pregnant. Endocrinology 131 (1992) 536-538
34. Chen W.Y., Wight D.C., Mehta B.V., Wagner T.E., and Kopchick J.J. Glycine 119 of bovine growth hormone is critical for growth-promoting activity. Mol. Endocrinol. 5 (1991) 1845-1852
35. Hammer R.E., Brinster R.L., Rosenfeld M.G., Evans R.M., and Mayo K.E. Expression of human growth hormone-releasing factor in transgenic mice results in increased somatic growth. Nature 315 (1985) 413-419
36. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
37. Aronson Jr. N.N., and Touster O. Isolation of rat liver plasma membrane fragments in isotonic sucrose. Meth. Enzymol. 31 (1974) 90-102
38. Sotelo A.I., Bartke A., Kopchick J.J., Knapp J.R., and Turyn D. Growth hormone (GH) receptors, binding proteins and IGF-1 concentrations in the serum of transgenic mice expressing bovine GH agonist and antagonist. J. Endocrinol. 158 (1998) 53-59
39. Cramer S.D., Barnard R., Engbers C., Thordarson G., and Talamantes F. A mouse growth hormone binding protein RIA: concentrations in maternal serum during pregnancy. Endocrinology 130 (1992) 1074-1076
40. Sotelo A.I., Dominici F.P., Engbers C., Bartke A., Talamantes F., and Turyn D. Growth hormone-binding protein in normal mice and in transgenic mice expressing bovine growth hormone gene. Am. J. Physiol. 268 (1995) E745-E751
41. Sotelo A.I., Bartke A., and Turyn D. Effects of bovine growth hormone (GH) expression in transgenic mice on serum and pituitary immunoreactive mouse GH levels and pituitary GH releasing factor binding sites. Acta Endocrinologica 129 (1993) 446-452
42. González L., Sotelo A.I., Bartke A., and Turyn D. Up-regulation of growth hormone (GH) binding protein by mouse GH in transgenic mice over-expressing GH releasing hormone. J. Endocrinol. 163 (1999) 299-307
43. Frick G.P., Tai L.R., Baumbach W.R., and Goodman H.M. Tissue distribution, turnover, and glycosylation of the long and short isoforms in rat tissues. Endocrinology 139 (1998) 2824-2830
44. González L., Miquet J.G., Sotelo A.I., Bartke A., and Turyn D. Cytokine-inducible SH2 protein up-regulation is associated with desensitization of GH signaling in GHRH-transgenic mice. Endocrinology 143 (2002) 386-394
45. Miquet J.G., Sotelo A.I., Bartke A., and Turyn D. Suppression of growth hormone (GH) Janus tyrosine kinase 2/signal transducer and activator of transcription 5 signaling pathway in transgenic mice overexpressing bovine GH. Endocrinology 145 (2004) 2824-2832
46. Miquet J.G., Sotelo A.I., Dominici F.P., Bonkowski M.S., Bartke A., and Turyn D. Increased sensitivity to GH in liver of Ames dwarf (Prop1df/Prop1df) mice related to diminished CIS abundance. J. Endocrinol. 187 (2005) 387-397
47. Landsman T., and Waxman D.J. Role of the cytokine-induced SH2 domain-containing protein CIS in growth hormone receptor internalization. J. Biol. Chem. 280 (2005) 37471-37480
48. Baxter R.C., Zaltsman Z., and Turtle J.R. Induction of somatogenic receptors in livers of hypersomatotropic rats. Endocrinology. 111 (1982) 1020-1022
49. Carmignac D.F., Wells T., Carlsson L.M., Clark R.G., and Robinson I.C. Growth hormone (GH)-binding protein in normal and deficient dwarf rats. J. Endocrinol. 135 (1992) 447-457
50. Carmignac D.F., Robinson I.C., Enberg B., and Norstedt G. Growth hormone receptor regulation in deficient dwarf rats. J. Endocrinol. 138 (1993) 447-457
51. Sánchez-Jiménez F., Fielder P.J., Martinez R.R., Smith W.C., and Talamantes F. Hypophysectomy eliminates and growth hormone (GH) maintains the mispregnancy elevation in GH receptor and serum binding protein in the mouse. Endocrinology 126 (1990) 1270-1275
52. Barnard P., and Waters M.J. The serum growth hormone binding protein: pregnant with possibilities. J. Endocrinol. 153 (1997) 1-14
53. Aguilar R.C., Fernández H.N., Dellacha J.M., et al. Somatotropic andb lactotropic receptors in transgenic mice expressing human and bovine growth hormone. Transgenic Res. 1 (1992) 221-227