Interferon regulatory factor-1 regulates reconstituted extracellular matrix (rECM)-mediated apoptosis in human mammary epithelial cells

Oncogene

Volumn 26, Issue 14, 2007, Pages 2017-2026

  Bowie, M L ^a   Troch, M M ^a   Delrow, J ^b   Dietze, E C ^a   Bean, G R ^a   Ibarra, C ^a   Pandiyan, G ^a   Seewaldt, V L ^a,c  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

^c DUKE UNIVERSITY   (United States)

Author keywords

Apoptosis; Extracellular matrix; IRF 1; Mammary epithelial cells; Tamoxifen

Indexed keywords

CASPASE 3; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEIN P53; SMALL INTERFERING RNA; TAMOXIFEN;

APOPTOSIS; ARTICLE; BREAST CANCER; BREAST CELL; BREAST EPITHELIUM; CANCER CELL CULTURE; CELL SURFACE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INDUCTION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

ANTINEOPLASTIC AGENTS, HORMONAL; APOPTOSIS; CASPASES; CREB-BINDING PROTEIN; EPITHELIAL CELLS; EXTRACELLULAR MATRIX; HUMANS; INTERFERON REGULATORY FACTOR-1; INTERFERON-STIMULATED GENE FACTOR 3; MAMMARY GLANDS, HUMAN; MITOCHONDRIAL PROTEINS; RESPONSE ELEMENTS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TAMOXIFEN; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC;

HUMAN PAPILLOMAVIRUS TYPE 16;

EID: 34047158128     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210013     Document Type: Article

References (36)

1. Aberdam D, Virolle T, Simon-Assmann P. (2000). Transcriptional regulation of laminin gene expression. Microsc Res Tech 51: 228-237.
2. Bouker KB, Skaar TC, Fernandez DR, O'Brien KA, Riggins RB, Cao DH et al. (2004). Interferon regulatory factor-1 mediates the proapoptotic but not cell cycle arrest effects of the steroidal antiestrogen ICI 182,780 (faslodex, fulvestrant). Cancer Res 64: 4030-4039.
3. Bouker KB, Skaar TC, Riggins RB, Harburger DS, Fernandez DR, Zwart A et al. (2005). Interferon regulatory factor-1 (IRF-1) exhibits tumor suppressor activities in breast cancer associated with caspase activation and induction of apoptosis. Carcinogenesis 26: 1527-1535.
4. Bowie ML, Dietze EC, Delrow J, Bean GR, Troch MM, Marjoram RJ et al. (2004). Interferon-regulatory factor-1 is critical for tamoxifen-mediated apoptosis in human mammary epithelial cells. Oncogene 23: 8743-8755.
5. D'Ardenne AJ, Richman PI, Horton MA, McAulay AE, Jordan S. (1991). Co-ordinate expression of the alpha-6 integrin laminin receptor sub-unit and laminin in breast cancer. J Pathol 165: 213-220.
6. Dietze EC, Bowie ML, Mrózek K, Caldwell LE, Neal C, Marjoram RJ et al. (2005). CREB-binding protein regulates apoptosis and growth of HMECs grown in reconstituted ECM via laminin-5. J Cell Sci 118(Part 21): 5005-5022.
7. Dietze EC, Caldwell LE, Grupin SL, Mancini M, Seewaldt VL. (2001). Tamoxifen but not 4-hydroxytamoxifen initiates apoptosis in p53(-) normal human mammary epithelial cells by inducing mitochondrial depolarization. J Biol Chem 276: 5384-5394.
8. Dietze EC, Troch MM, Bean GR, Heffner JB, Bowie ML, Rosenberg P et al. (2004). Tamoxifen and tamoxifen ethyl bromide induce apoptosis in acutely damaged mammary epithelial cells through modulation of AKT activity. Oncogene 23: 3851-3862.
9. Farrelly N, Lee YJ, Oliver J, Dive C, Streuli CH. (1999). Extracellular matrix regulates apoptosis in mammary epithelium through a control on insulin signaling. J Cell Biol 144: 1337-1348.
10. Folkman J, Moscona A. (1978). Role of cell shape in growth control. Nature 273: 345-349.
11. Goodman RH, Smolik S. (2000). CBP/p300 in cell growth, transformation, and development. Genes Dev 14: 1553-1577.
12. Gu Z, Lee RY, Skaar TC, Bouker KB, Welch JN, Lu J et al. (2002). Association of interferon regulatory factor-1, nucleophosmin, nuclear factor-kappaB, and cyclic AMP response element binding with acquired resistance to Faslodex (ICI 182,780). Cancer Res 62: 3428-3437.
13. Henderson YC, Chou M, Deisseroth AB. (1997). Interferon regulatory factor 1 induces the expression of the interferon-stimulated genes. Br J Haematol 96: 566-575.
14. Imam AM, Ackrill AM, Dale TC, Kerr IM, Stark GR. (1990). Transcription factors induced by interferons alpha and gamma. Nucleic Acids Res 18: 6573-6580.
15. Kelly JM, Porter AC, Chernajovsky Y, Gilbert CS, Stark GR, Kerr IM. (1986). Characterization of a human gene inducible by alpha- and beta-interferons and its expression in mouse cells. EMBO J 5: 1601-1606.
16. Kelly MJ, Levin ER. (2001). Rapid actions of plasma membrane estrogen receptors. Trends Endocrinol Metab 12: 152-156.
17. Kessler DS, Levy DE, Darnell Jr JE. (1988). Two interferon-induced nuclear factors bind a single promoter element in interferon-stimulated genes. Proc Natl Acad Sci USA 85: 8521-8525.
18. Kim PK, Armstrong M, Liu Y, Yan P, Bucher B, Zuckerbraun BS et al. (2004). IRF-1 expression induces apoptosis and inhibits tumor growth in mouse mammary cancer cells in vitro and in vivo. Oncogene 23: 1125-1135.
19. Levy DE, Kessler DS, Pine R, Reich N, Darnell Jr JE. (1988). Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control. Genes Dev 2: 383-393.
20. Marquez DC, Pietras RJ. (2001). Membrane-associated binding sites for estrogen contribute to growth regulation of human breast cancer cells. Oncogene 20: 5420-5430.
21. Miyamoto M, Fujita T, Kimura Y, Maruyama M, Harada H, Sudo Y et al. (1988). Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-beta gene regulatory elements. Cell 54: 903-913.
22. Ossina NK, Cannas A, Powers VC, Fitzpatrick PA, Knight JD, Gilbert JR et al. (1997). Interferon-gamma modulates a p53-independent apoptotic pathway and apoptosis-related gene expression. J Biol Chem 272: 16351-16357.
23. Parrington J, Rogers NC, Gewert DR, Pine R, Veals SA, Levy DE et al. (1993). The interferon-stimulable response elements of two human genes detect overlapping sets of transcription factors. Eur J Biochem 214: 617-626.
24. Petersen OW, Ronnov-Jensen L, Howlett AR, Bissell MJ. (1992). Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells. Proc Natl Acad Sci USA 89: 9064-9068.
25. Pizzoferrato E, Liu Y, Gambotto A, Armstrong MJ, Stang MT, Gooding WE et al. (2004). Ectopic expression of interferon regulatory factor-1 promotes human breast cancer cell death and results in reduced expression of survivin. Cancer Res 64: 8381-8388.
26. Porta C, Hadj-Slimane R, Nejmeddine M, Pampin M, Tovey MG, Espert L et al. (2005). Interferons alpha and gamma induce p53-dependent and p53-independent apoptosis, respectively. Oncogene 24: 605-615.
27. Robyr D, Wolffe AP, Wahli W. (2000). Nuclear hormone receptor coregulators in action: diversity for shared tasks. Mol Endocrinol 14: 329-347.
28. Romeo G, Fiorucci G, Chiantore MV, Percario ZA, Vannucchi S, Affabris E. (2002). IRF-1 as a negative regulator of cell proliferation. J Interferon Cytokine Res 22: 39-47.
29. Seewaldt VL, Kim JH, Caldwell LE, Johnson BS, Swisshelm K, Collins SJ. (1997). All-trans-retinoic acid mediates G1 arrest but not apoptosis of normal human mammary epithelial cells. Cell Growth Differ 8: 631-641.
30. Seewaldt VL, Mrozek K, Sigle R, Dietze EC, Heine K, Hockenberry DM et al. (2001). Suppression of p53 function in normal human mammary epithelial cells increases sensitivity to extracellular matrix-induced apoptosis. J Cell Biol 155: 471-486.
31. Stupack DG, Cheresh DA. (2002). Get a ligand, get a life: integrins, signaling and cell survival. J Cell Sci 115(Part 19): 3729-3738.
32. Tamura T, Ishihara M, Lamphier MS, Tanaka N, Oishi I, Aizawa S et al. (1995). An IRF-1 dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes. Nature 376: 596-599.
33. Tanaka N, Ishihara M, Lamphier MS, Nozawa H, Matsuyama T, Mak TW et al. (1996). Cooperation of the tumour suppressors IRF-1 and p53 in response to DNA damage. Nature 382: 816-818.
34. Veals SA, Schindler C, Leonard D, Fu XY, Aebersold R, Darnell Jr JE et al. (1992). Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins. Mol Cell Biol 12: 3315-3324.
35. Vo N, Goodman RH. (2001). CREB-binding protein and p300 in transcriptional regulation. J Biol Chem 276: 13505-13508.
36. Yokota S, Okabayashi T, Yokosawa N, Fujii N. (2004). Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 contributes to inhibition of the interferon signaling pathway. J Virol 78: 4591-4598.