메뉴 건너뛰기




Volumn 40, Issue 2, 2007, Pages 163-171

Structurally conserved aromaticity of Tyr249 and Phe 264 in helix 7 is important for toxicity of the Bacillus thuringiensis Cry4Ba toxin

Author keywords

Bacillus thuringiensis; Conserved aromaticity; Larvicidal activity; Site directed mutagenesis; endotoxin

Indexed keywords

AEDES AEGYPTI; BACILLUS THURINGIENSIS; ESCHERICHIA COLI;

EID: 34047153317     PISSN: 12258687     EISSN: 02191024     Source Type: Journal    
DOI: 10.5483/bmbrep.2007.40.2.163     Document Type: Article
Times cited : (9)

References (41)
  • 1
    • 0035957098 scopus 로고    scopus 로고
    • Role of a-helix 7 of Bacillus thuringiensis Cry1Ab δ-endotoxin in membrane insertion, structural stability, and ion channel activity
    • Alcantara, E. P., Alzate, O., Lee, M. K., Curtiss, A. and Dean, D. H. (2001) Role of a-helix 7 of Bacillus thuringiensis Cry1Ab δ-endotoxin in membrane insertion, structural stability, and ion channel activity. Biochemistry 40, 2540-2547.
    • (2001) Biochemistry , vol.40 , pp. 2540-2547
    • Alcantara, E.P.1    Alzate, O.2    Lee, M.K.3    Curtiss, A.4    Dean, D.H.5
  • 4
    • 0034702838 scopus 로고    scopus 로고
    • Membrane binding of peptides containing both basic and aromatic residues: Experimental studies with peptides corresponding to the scaffolding region of caveolin and the effector region of MARCKS
    • Arbuzova, A., Wang, L., Wang, J., Hangyás-Mihályne, G., Murray, D., Honig, B. and Mclaughlin, S. (2000) Membrane binding of peptides containing both basic and aromatic residues: experimental studies with peptides corresponding to the scaffolding region of caveolin and the effector region of MARCKS. Biochemistry 39, 10330-10339.
    • (2000) Biochemistry , vol.39 , pp. 10330-10339
    • Arbuzova, A.1    Wang, L.2    Wang, J.3    Hangyás-Mihályne, G.4    Murray, D.5    Honig, B.6    Mclaughlin, S.7
  • 5
    • 34047106159 scopus 로고    scopus 로고
    • Becker, N. and Margalit, J. (1993) Use of Bacillus thuringiensis subsp. israelensis against mosquitoes and blackflies; in Bacillus thuringiensis, an Environmental Biopesticide: Theory and Practice, Entwistle, P. F., Cory, J. S., Bailey, M. J. and Higgs, S. (eds.), pp. 147-170, John Wiley and Sons, New York, USA.
    • Becker, N. and Margalit, J. (1993) Use of Bacillus thuringiensis subsp. israelensis against mosquitoes and blackflies; in Bacillus thuringiensis, an Environmental Biopesticide: Theory and Practice, Entwistle, P. F., Cory, J. S., Bailey, M. J. and Higgs, S. (eds.), pp. 147-170, John Wiley and Sons, New York, USA.
  • 6
    • 33645510751 scopus 로고    scopus 로고
    • Assessing the role of aromatic residues in the amyloid aggregation of human muscle acylphosphatase
    • Bemporad, F., Taddei, N., Stefani, M. and Chiti, F. (2006) Assessing the role of aromatic residues in the amyloid aggregation of human muscle acylphosphatase. Protein Sci. 15, 862-870.
    • (2006) Protein Sci , vol.15 , pp. 862-870
    • Bemporad, F.1    Taddei, N.2    Stefani, M.3    Chiti, F.4
  • 7
    • 16244392435 scopus 로고    scopus 로고
    • Crystal structure of the mosquito-larvicidal toxin Cry4Ba and its biological implications
    • Boonserm, P., Davis, P., Ellar, D. J. and Li, J. (2005) Crystal structure of the mosquito-larvicidal toxin Cry4Ba and its biological implications. J. Mol. Biol. 348, 363-382.
    • (2005) J. Mol. Biol , vol.348 , pp. 363-382
    • Boonserm, P.1    Davis, P.2    Ellar, D.J.3    Li, J.4
  • 8
    • 33646257356 scopus 로고    scopus 로고
    • Structure of the functional form of the mosquitolarvicidal Cry4Aa toxin from Bacillus thuringiensis at a 2.8-angstorm resolution
    • Boonserm, P., Min, M., Angsuthanasombat, C. and Lescar, J. (2006) Structure of the functional form of the mosquitolarvicidal Cry4Aa toxin from Bacillus thuringiensis at a 2.8-angstorm resolution. J. Bacteriol. 188, 3391-3401.
    • (2006) J. Bacteriol , vol.188 , pp. 3391-3401
    • Boonserm, P.1    Min, M.2    Angsuthanasombat, C.3    Lescar, J.4
  • 9
    • 0033609498 scopus 로고    scopus 로고
    • The aromatic residues Trp and Phe have different effects on the positioning of a transmembrane helix in the microsomal membrane
    • Braun, P. and Von Heijne, G. (1999) The aromatic residues Trp and Phe have different effects on the positioning of a transmembrane helix in the microsomal membrane. Biochemistry 38, 9778-9782.
    • (1999) Biochemistry , vol.38 , pp. 9778-9782
    • Braun, P.1    Von Heijne, G.2
  • 10
    • 0032861219 scopus 로고    scopus 로고
    • Amino acid substitution in α-helix 7 of Cry1Ac delta-endotoxin of Bacillus thuringiensis leads to enhanced toxicity to Helicoverpa armigera Hubner
    • Chandra, A., Ghosh, P., Mandaokar, A. D., Bera, A. K., Sharma, R. P., Das, S. and Kumar, P. A. (1999) Amino acid substitution in α-helix 7 of Cry1Ac delta-endotoxin of Bacillus thuringiensis leads to enhanced toxicity to Helicoverpa armigera Hubner. FEBS Lett. 458, 175-179.
    • (1999) FEBS Lett , vol.458 , pp. 175-179
    • Chandra, A.1    Ghosh, P.2    Mandaokar, A.D.3    Bera, A.K.4    Sharma, R.P.5    Das, S.6    Kumar, P.A.7
  • 11
    • 0035313205 scopus 로고    scopus 로고
    • How Bacillus thuringiensis has evolved specific toxins to colonize the insect world
    • De Maagd, R. A., Bravo, A. and Crickmore, N. (2001) How Bacillus thuringiensis has evolved specific toxins to colonize the insect world. Trends Genet. 17, 193-199.
    • (2001) Trends Genet , vol.17 , pp. 193-199
    • De Maagd, R.A.1    Bravo, A.2    Crickmore, N.3
  • 12
    • 0035214724 scopus 로고    scopus 로고
    • Crystallization of the Bacillus thuringiensis toxin Cry1Ac and its complex with the receptor ligand N-acetyl-D-galactosamine
    • Derbyshire, D. J., Ellar, D. J. and Li, J. (2001) Crystallization of the Bacillus thuringiensis toxin Cry1Ac and its complex with the receptor ligand N-acetyl-D-galactosamine. Acta Crystallogr. 57, 1938-1944.
    • (2001) Acta Crystallogr , vol.57 , pp. 1938-1944
    • Derbyshire, D.J.1    Ellar, D.J.2    Li, J.3
  • 13
    • 32344442117 scopus 로고    scopus 로고
    • Drechsler, A., Potrich, C., Sabo, J. K., Frisanco, M., Guella., Della Serra, M., Anderluh, G., Separovic, F. and Norton, R. S. (2006) Structure and activity of the N-terminal region of the eukaryotic cytolysin equinatoxin II. Biochemistry 45, 1818-1828.
    • Drechsler, A., Potrich, C., Sabo, J. K., Frisanco, M., Guella., Della Serra, M., Anderluh, G., Separovic, F. and Norton, R. S. (2006) Structure and activity of the N-terminal region of the eukaryotic cytolysin equinatoxin II. Biochemistry 45, 1818-1828.
  • 14
    • 0032514753 scopus 로고    scopus 로고
    • The structure and organization within the membrane of the helices composing the pore-forming domain of Bacillus thuringiensis delta-endotoxin are consistent with an "umbrella-like" structure of the pore
    • Gazit, E., La Rocca, P., Samson, M. S. and Shai, Y. (1998) The structure and organization within the membrane of the helices composing the pore-forming domain of Bacillus thuringiensis delta-endotoxin are consistent with an "umbrella-like" structure of the pore. Proc. Natl. Acad. Sci. USA 95, 12289-12294.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 12289-12294
    • Gazit, E.1    La Rocca, P.2    Samson, M.S.3    Shai, Y.4
  • 15
    • 0004168208 scopus 로고    scopus 로고
    • Testing the difference between two means of independent samples
    • Glover, T. and Mitchell, K, eds, pp, McGraw-Hill Higher Education, New York
    • Glover, T. and Mitchell, K. (2002). Testing the difference between two means of independent samples; in An Introduction to Biostatistics Glover, T. and Mitchell, K. (eds.), pp. 163-168, McGraw-Hill Higher Education, New York.
    • (2002) An Introduction to Biostatistics , pp. 163-168
    • Glover, T.1    Mitchell, K.2
  • 16
    • 0037181168 scopus 로고    scopus 로고
    • Cadherin-like receptor binding facilitates proteolytic clevage of helix α-1 in domain I and oligomer prepore formation of Bacillus thuringiensis Cry1Ab toxin
    • Gómez, I., Sánchez, J., Miranda, R., Bravo, A., Gill, S. and Soberon, M. (2002) Cadherin-like receptor binding facilitates proteolytic clevage of helix α-1 in domain I and oligomer prepore formation of Bacillus thuringiensis Cry1Ab toxin. FEBS Lett. 513, 242-246.
    • (2002) FEBS Lett , vol.513 , pp. 242-246
    • Gómez, I.1    Sánchez, J.2    Miranda, R.3    Bravo, A.4    Gill, S.5    Soberon, M.6
  • 18
    • 1342283143 scopus 로고    scopus 로고
    • Effects of essential carbohydrate/aromatic stacking interaction with Tyr100 and Phe259 on substrate binding of cyclodextrin glycosyltransferase from alkalophilic Bacillus sp. 1011
    • Haga, K., Kanai, R., Sakamoto, O., Aoyagi, M., Harata, K. and Yamane, K. (2003) Effects of essential carbohydrate/aromatic stacking interaction with Tyr100 and Phe259 on substrate binding of cyclodextrin glycosyltransferase from alkalophilic Bacillus sp. 1011. J. Biochem. 134, 881-891.
    • (2003) J. Biochem , vol.134 , pp. 881-891
    • Haga, K.1    Kanai, R.2    Sakamoto, O.3    Aoyagi, M.4    Harata, K.5    Yamane, K.6
  • 19
    • 0037952941 scopus 로고    scopus 로고
    • Specific mutations within the α4-α5 loop of the Bacillus thuringiensis Cry4B toxin reveal a crucial role of Asn-166 and Tyr-170
    • Kanintronkul, Y., Sramala, I., Katzenmeier, G., Panyim, S. and Angsuthanasombat, C. (2003) Specific mutations within the α4-α5 loop of the Bacillus thuringiensis Cry4B toxin reveal a crucial role of Asn-166 and Tyr-170. Mol. Biotechnol. 24, 11-19.
    • (2003) Mol. Biotechnol , vol.24 , pp. 11-19
    • Kanintronkul, Y.1    Sramala, I.2    Katzenmeier, G.3    Panyim, S.4    Angsuthanasombat, C.5
  • 20
    • 26844482932 scopus 로고    scopus 로고
    • Insertion behavior of the Bacillus thuringiensis Cry4Ba insecticidal protein into lipid monolayers
    • Kanintronkul, Y., Srikhirin, T., Angsuthanasombat, C. and Kerdcharoen, T. (2005) Insertion behavior of the Bacillus thuringiensis Cry4Ba insecticidal protein into lipid monolayers. Arch. Biochem. Biophys. 442, 180-186.
    • (2005) Arch. Biochem. Biophys , vol.442 , pp. 180-186
    • Kanintronkul, Y.1    Srikhirin, T.2    Angsuthanasombat, C.3    Kerdcharoen, T.4
  • 21
    • 0028002221 scopus 로고
    • Mechanism of action of Bacillus thuringiensis insecticidal delta-endotoxins
    • Knowles, B. H. (1994) Mechanism of action of Bacillus thuringiensis insecticidal delta-endotoxins. Adv. Insect Physiol. 24, 275-308.
    • (1994) Adv. Insect Physiol , vol.24 , pp. 275-308
    • Knowles, B.H.1
  • 22
    • 33744948449 scopus 로고    scopus 로고
    • Novel preparation and characterisation of the α4-loop-α5 membrane perturbing peptide from the Bacillus thuringiensis Cry4Ba toxin
    • Leetachewa, S., Katzenmeier, G. and Angsuthanasombat, C. (2006) Novel preparation and characterisation of the α4-loop-α5 membrane perturbing peptide from the Bacillus thuringiensis Cry4Ba toxin. J. Biochem. Mol. Biol. 39, 270-277.
    • (2006) J. Biochem. Mol. Biol , vol.39 , pp. 270-277
    • Leetachewa, S.1    Katzenmeier, G.2    Angsuthanasombat, C.3
  • 23
    • 0026050639 scopus 로고
    • Crystal structure of insecticidal δ-endotoxin from Bacillus thuringiensis at 2.5Å resolution
    • Li, J. D., Carroll, J. and Ellar, D. J. (1991) Crystal structure of insecticidal δ-endotoxin from Bacillus thuringiensis at 2.5Å resolution. Nature 353, 815-821.
    • (1991) Nature , vol.353 , pp. 815-821
    • Li, J.D.1    Carroll, J.2    Ellar, D.J.3
  • 24
    • 29244443658 scopus 로고    scopus 로고
    • Asn183 in α5 is essential for oligomerisation and toxicity of the Bacillus thuringiensis Cry4Ba toxin
    • Likitvivatanavong, S., Katzenmeier, G. and Angsuthanasombat, C. (2006) Asn183 in α5 is essential for oligomerisation and toxicity of the Bacillus thuringiensis Cry4Ba toxin. Arch. Biochem. Biophys. 445, 46-55.
    • (2006) Arch. Biochem. Biophys , vol.445 , pp. 46-55
    • Likitvivatanavong, S.1    Katzenmeier, G.2    Angsuthanasombat, C.3
  • 25
    • 0038604282 scopus 로고    scopus 로고
    • A novel mechanism of pore formation: Membrane penetration by the N-terminal amphipathic region of equinatoxin
    • Malovrh, P., Viero, G., Serra, M. D., Podlesek, Z., Lakey, J. H., Macek, P., Menestrina, G. and Anderluh, G. (2003) A novel mechanism of pore formation: membrane penetration by the N-terminal amphipathic region of equinatoxin. J. Biol. Chem. 278, 22678-22685.
    • (2003) J. Biol. Chem , vol.278 , pp. 22678-22685
    • Malovrh, P.1    Viero, G.2    Serra, M.D.3    Podlesek, Z.4    Lakey, J.H.5    Macek, P.6    Menestrina, G.7    Anderluh, G.8
  • 26
    • 0033527563 scopus 로고    scopus 로고
    • Helix 4 of the Bacillus thuringiensis Cry1Aa toxin lines the lumen of the ion channel
    • Masson, L., Tabashnik, B. E., Liu, Y. B., Brousseau, R. and Schwartz, J. L. (1999) Helix 4 of the Bacillus thuringiensis Cry1Aa toxin lines the lumen of the ion channel. J. Biol. Chem. 274, 31996-32000.
    • (1999) J. Biol. Chem , vol.274 , pp. 31996-32000
    • Masson, L.1    Tabashnik, B.E.2    Liu, Y.B.3    Brousseau, R.4    Schwartz, J.L.5
  • 27
    • 0034980642 scopus 로고    scopus 로고
    • Structure of Cry2Aa suggests an unexpected receptor binding epitope
    • Morse, R. J., Yamamoto, T. and Stroud, R. M. (2001) Structure of Cry2Aa suggests an unexpected receptor binding epitope. Structure 9, 409-417.
    • (2001) Structure , vol.9 , pp. 409-417
    • Morse, R.J.1    Yamamoto, T.2    Stroud, R.M.3
  • 28
    • 0035831331 scopus 로고    scopus 로고
    • Structural and functional studies of alpha-helix 5 region from Bacillus thuringiensis Cry1Ab delta-endotoxin
    • Nunez-Valdez, M., Sánchez, J., Lina, L., Güereca, L. and Bravo, A. (2001) Structural and functional studies of alpha-helix 5 region from Bacillus thuringiensis Cry1Ab delta-endotoxin. Biochim. Biophys. Acta 1546, 122-131.
    • (2001) Biochim. Biophys. Acta , vol.1546 , pp. 122-131
    • Nunez-Valdez, M.1    Sánchez, J.2    Lina, L.3    Güereca, L.4    Bravo, A.5
  • 30
    • 16544374775 scopus 로고    scopus 로고
    • Effect of specific mutations in helix α7 of domain I on the stability and crystallization
    • Park, H. W. and Federici, B. A. (2004) Effect of specific mutations in helix α7 of domain I on the stability and crystallization. Mol. Biotechnol. 27, 89-100.
    • (2004) Mol. Biotechnol , vol.27 , pp. 89-100
    • Park, H.W.1    Federici, B.A.2
  • 31
    • 3142734918 scopus 로고    scopus 로고
    • Aromaticity of Tyr-202 in the α4-α5 loop is essential for toxicity of the Bacillus thuringiensis Cry4A toxin
    • Pornwiroon, W., Katzenmeier, G., Panyim, S. and Angsuthanasombat, C. (2004) Aromaticity of Tyr-202 in the α4-α5 loop is essential for toxicity of the Bacillus thuringiensis Cry4A toxin. J. Biochem. Mol. Biol. 37, 292-297.
    • (2004) J. Biochem. Mol. Biol , vol.37 , pp. 292-297
    • Pornwiroon, W.1    Katzenmeier, G.2    Panyim, S.3    Angsuthanasombat, C.4
  • 32
    • 1642501561 scopus 로고    scopus 로고
    • Ion channels formed in planar lipid bilayers by the diptheran-specific Cry4Ba Bacillus thuringiensis and its α1-α5 fragment
    • Puntheeranurak, T., Uawithya, P., Potvin, L., Angsuthanasombat, C. and Schwartz, J. L. (2004) Ion channels formed in planar lipid bilayers by the diptheran-specific Cry4Ba Bacillus thuringiensis and its α1-α5 fragment. Mol. Membr. Biol. 21, 67-74.
    • (2004) Mol. Membr. Biol , vol.21 , pp. 67-74
    • Puntheeranurak, T.1    Uawithya, P.2    Potvin, L.3    Angsuthanasombat, C.4    Schwartz, J.L.5
  • 33
    • 11244299331 scopus 로고    scopus 로고
    • Unfolding events in the water-soluble monomeric Cry1Ab toxin during transition to oligomeric pre-pore and membrane-inserted pore channel
    • Rausell, C., Pardo-López, L., Sánchez, J., Muñoz-Garay, C., Morera, C., Soberón, M. and Bravo, A. (2004) Unfolding events in the water-soluble monomeric Cry1Ab toxin during transition to oligomeric pre-pore and membrane-inserted pore channel. J. Biol. Chem. 279, 55168-55175.
    • (2004) J. Biol. Chem , vol.279 , pp. 55168-55175
    • Rausell, C.1    Pardo-López, L.2    Sánchez, J.3    Muñoz-Garay, C.4    Morera, C.5    Soberón, M.6    Bravo, A.7
  • 35
    • 0030785699 scopus 로고    scopus 로고
    • Restriction of intramolecular movements within the Cry1Aa toxin molecule of Bacillus thuringiensis through disulfide bond engineering
    • Schwartz, J. L., Juteau, M., Grochulski, P., Cygler, M., Prefontaine, G., Brousseau, R. and Masson, L. (1997) Restriction of intramolecular movements within the Cry1Aa toxin molecule of Bacillus thuringiensis through disulfide bond engineering. FEBS Lett. 410, 397-402.
    • (1997) FEBS Lett , vol.410 , pp. 397-402
    • Schwartz, J.L.1    Juteau, M.2    Grochulski, P.3    Cygler, M.4    Prefontaine, G.5    Brousseau, R.6    Masson, L.7
  • 36
    • 0035761118 scopus 로고    scopus 로고
    • Charged residues screening in helix 4 of the Bacillus thuringiensis Cry4B toxin reveals one critical residue for larvicidal activity
    • Sramala, I., Leetachewa, S., Krittanai, C., Katzenmeier, G., Panyim, S. and Angsuthanasombat, C. (2001) Charged residues screening in helix 4 of the Bacillus thuringiensis Cry4B toxin reveals one critical residue for larvicidal activity. J. Biochem. Mol. Biol. Biophys. 5, 219-225.
    • (2001) J. Biochem. Mol. Biol. Biophys , vol.5 , pp. 219-225
    • Sramala, I.1    Leetachewa, S.2    Krittanai, C.3    Katzenmeier, G.4    Panyim, S.5    Angsuthanasombat, C.6
  • 39
    • 15744376728 scopus 로고    scopus 로고
    • Structural requirements of the unique disulphide bond and the proline-rich motif within the α4-α5 loop for larvicidal activity of the Bacillus thuringiensis Cry4Aa δ-endotoxin
    • Tapaneeyakorn, S., Pornwiroon, W., Katzenmeier, G. and Angsuthanasombat, C. (2005) Structural requirements of the unique disulphide bond and the proline-rich motif within the α4-α5 loop for larvicidal activity of the Bacillus thuringiensis Cry4Aa δ-endotoxin. Biochem. Biophys. Res. Commun. 330, 519-525.
    • (2005) Biochem. Biophys. Res. Commun , vol.330 , pp. 519-525
    • Tapaneeyakorn, S.1    Pornwiroon, W.2    Katzenmeier, G.3    Angsuthanasombat, C.4
  • 40
    • 0031923098 scopus 로고    scopus 로고
    • Effects on larvicidal activity of single proline substitutions in alpha 3 or alpha 4 of the Bacillus thuringiensis Cry4B toxin
    • Uawithya, P., Tuntitippawan, T., Katzenmeier, G., Panyim, S. and Angsuthanasombat, C. (1998) Effects on larvicidal activity of single proline substitutions in alpha 3 or alpha 4 of the Bacillus thuringiensis Cry4B toxin. Biochem. Mol. Biol. Int. 44, 825-832.
    • (1998) Biochem. Mol. Biol. Int , vol.44 , pp. 825-832
    • Uawithya, P.1    Tuntitippawan, T.2    Katzenmeier, G.3    Panyim, S.4    Angsuthanasombat, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.