Ciclosporin reduces paracellin-1 expression and magnesium transport in thick ascending limb cells

Nephrology Dialysis Transplantation

Volumn 22, Issue 4, 2007, Pages 1033-1040

  Chang, Chiz Tzung ^a,b   Hung, Cheng Chieh ^b   Tian, Ya Chung ^b   Yang, Chih Wei ^b   Wu, Mai Szu ^b,c  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Ciclosporin; Magnesium transport; Paracellin 1; PCLN 1; Thick ascending limb

Indexed keywords

CLAUDIN; CYCLOSPORIN A; MAGNESIUM ION; MESSENGER RNA; PARACELLIN 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL GROWTH; CELL IMMORTALIZATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FLUORESCENCE ANALYSIS; GENETIC CODE; HYPOMAGNESEMIA; INCUBATION TIME; KIDNEY TUBULE CELL; MALE; MICRODISSECTION; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL TRANSPORT; CELL SURVIVAL; CELLS, CULTURED; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; IMMUNOSUPPRESSIVE AGENTS; LOOP OF HENLE; MAGNESIUM; MALE; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; RNA, MESSENGER;

EID: 34047145486     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfl817     Document Type: Article

References (20)

1. Quamme GA. Renal magnesium handling: New insights in understanding old problems. Kidney Int 1997; 52: 1180-1195
2. Wong V, Goodenough DA. Paracellular channels! Science 1999; 285: 62
3. 2+ resorption. Science 1999; 285: 103-106
4. Clarke H, Ryan MP. Cyclosporine A-induced alterations in magnesium homeostasis in the rat. Life Sci 1999; 64: 1295-1306
5. - co-transport activity in cultured mouse medullary thick ascending limb cells. Kidney Int 2000; 58: 1652-1663
6. Cartier N, Lacave R, Vallet V et al. Establishment of renal proximal tubule cell lines by targeted oncogenesis in transgenic mice using the L-pyruvate kinase-SV40 (T) antigen hybrid gene. J Cell Sci 1993; 104695-704
7. Acharya P, Beckel J, Ruiz WG et al. Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium. Am J Physiol Renal Physiol 2004; 287: F305-F318
8. Raju B, Murphy E, Levy LA, Hall RD, London RE. A fluorescent indicator for measuring cytosolic free magnesium. Am J Physiol 1989; 256: C540-C548
9. 2+ and magnesium depletion in isolated renal thick ascending limb cells. J Clin Invest 1991; 88: 1255-1264
10. 2+ uptake in mouse distal convoluted tubule cells. Biochem Biophys Res Commun 2006; 341: 742-748
11. 2+ transport function of Claudin-16. J Clin Invest 2006; 116: 878-891, Epub 2006, Mar 2009
12. Wu MS, Bens M, Cluzeaud F, Vandewalle A. Role of F-actin in the activation of Na(+)-K(+)-Cl- co-transport by forskolin and vasopressin in mouse kidney cultured thick ascending limb cells. J Membr Biol 1994; 142: 323-336
13. Quamme GA, de Rouffignac C. Epithelial magnesium transport and regulation by the kidney. Frontiers Biosci 2000; 5: D694-711
14. Milionis HJ, Alexandrides GE, Liberopoulos EN et al. Hypomagnesemia and concurrent acid-base and electrolyte abnormalities in patients with congestive heart failure. Eur J Heart Fail 2002; 4: 167-173
15. Ikari A, Hirai N, Shiroma M et al. Association of paracellin-1 with ZO-1 augments paracellular barrier and divalent cation permeability. J Biol Chem 2004; 279: 54826-54832
16. 2+ ions. Nephrol Dial Transplant 2003; 18: 2262-2268
17. Hong F, Lee J, Piao YJ et al. Transgenic mice over-expressing cyclophilin A are resistant to cyclosporin A-induced nephrotoxicity via peptidyl-prolyl cis-trans isomerase activity. Biochem Biophys Res Commun 2004; 316: 1073-1080
18. Wu MS, Yang CW, Bens M et al. Cyclosporin inhibits nitric oxide production in medullary ascending limb cultured cells. Nephrol Dial Transplant 1998; 13: 2814-2820
19. Wu MS, Yang CW, Chang CT, Bens M, Vandewalle A. Cyclosporin increases the density of angiotensin II subtype 1 (AT1) receptors in mouse medullary thick ascending limb cells. Nephrol Dial Transplant 2003; 18: 1458-1465
20. Chang CT, Hung CC, Yang CW, Vandewalle A, Wu MS. Cyclosporine decreases prostaglandin E2 production in mouse medullary thick ascending limb cultured cells. Transpl Int 2005; 18: 871-878