Cyclosporin inhibits nitric oxide production in medullary ascending limb cultured cells

Nephrology Dialysis Transplantation

Volumn 13, Issue 11, 1998, Pages 2814-2820

  Wu, Mai Szu ^a   Yang, Chih Wei ^a   Bens, Marcelle ^b   Yu, Hsiao Mei ^a   Huang, Jeng Yi ^a   Wu, Chin Herng ^a   Huang, Chiu Ching ^a   Vandewalle, Alain ^b  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b INSERM   (France)

Author keywords

Cultured cells; Cyclosporin; Kidney; Nephrotoxicity; Nitric oxide; Thick ascending limbs

Indexed keywords

AMINOGUANIDINE; ARGININE METHYL ESTER; BACTERIUM LIPOPOLYSACCHARIDE; CYCLOSPORIN A; MESSENGER RNA; NITRIC OXIDE; NITRITE; PHORBOL 13 ACETATE 12 MYRISTATE;

ANIMAL CELL; ARTICLE; DISEASE MODEL; KIDNEY CELL CULTURE; KIDNEY MEDULLA; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 0031756772     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.ndt.a027801     Document Type: Article

References (39)

1. Welch GN, Upchurch GR, Loscalzo J. Nitric oxide as a vascular modulator. Blood Reviews 1995; 9: 262 269
2. Moncada S, Higgs EA. Mechanism of disease: The L-arginine nitric oxide pathway. N Engl J Med 1993; 329: 2002 2012
3. Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 1991; 43: 109 142
4. Palmer RMJ, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987; 327: 524 526
5. Farrell AJ, Blake DR. Nitric oxide. Ann Rheum Dis 1996; 55: 7 20
6. Snyder S, Bredt DS. Biological roles of nitric oxide. Scient Amer 1992; 166: 28 35
7. Xie Q, Cho H, Calaycay J, Mumford R, Swiderek K, Lee T, Ding A, Troso T, Nathan, C. Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science 1992; 256: 225-228
8. Vane JR. The endothelium: maestro of the blood circulation. Proc R Soc Lond B 1994; 343: 225 246
9. Romero JC, Lahera V, Salom MG, Biondi ML. Role of endothelium-derived relaxing factor nitric oxide on renal function. J Am Soc Nephrol 1992; 2: 1371 1387
10. Stoos BA, Carretero, OA, Farhy RD, Scicli G, Garvin JL. Endothelium-derived relaxing factor inhibits transport and increases cGMP content in cultured mouse cortical collecting duct cells. J Clin Invest 1992; 89: 761 765
11. Ishii K, Chang B, Kerwin Jr, JF, Wagenaar FL, Huang Z-J, Murad F. Formation of endothelium-derived relaxing factor in porcine kidney epithelial LLC-PK1 cells: an intra- and intercellular messenger for activation of soluble guanylate cyclase. J Pharmocol Exp Ther 1991; 256: 38-43
12. Tojo A, Gross SS, Zhang L, Tisher C, Schmidt HH, Wilcox CS, Madsen KM. Immunocytochemical localization of distinct isoforms of nitric oxide synthase in juxaglomerular apparatus of normal rat kidney. J Am Soc Nephrol 1994; 4: 1438 1447
13. Mohaupt MG, Elzic JL, Ahn KY, Clapp WL, Wilcox CS, Kone BC. Differential expression and induction of mRNAs encoding two inducible nitric oxide synthases in rat kidney. Kidney Int 1994; 46: 653 665
14. Morrissey JJ, McCracken R, Kaneto H, Vehaskari M, Montani D, Klahr S. Localization of an inducible nitric oxide synthase mRNA in the normal kidney. Kidney Int 1994; 45: 998 1005
15. Brezis M, Heymen SN, Dinosur D. Role of nitric oxide in renal medullary oxygenation. J Clin Invest 1991; 88: 390-395
16. Myers BD, Ross J, Newton L, Lustcher J, Perlrath M. Cyclosporin-associated nephropathy. N Engl J Med 1984; 311: 699-705
17. Devarajan P, Kaskel FJ, Albeit LA, Moore LC. Cyclosporine nephrotoxicity: blood volume, sodium conservation, and renal hemodynamics. Am J Physiol 1989; 256: F71-F78
18. McNally PG, Feehally J. Pathophysiology of cyclosporin A nephrotoxicity: experimental and clinical observation. Nephrol Dial Transplant 1992; 7: 791-804
19. Marumo T, Nakaki T, Hishikawa K, Suzuki H, Kato R, Saruta T. Cyclosporin A inhibits nitric oxide synthase induction in vascular smooth muscle cells. Hypertension 1995; 25 [part 2]: 764-768
20. Gallego MJ, Villalón AG, Farre AL, Garcia JL, Garrón MP, Casado S, Hernad S, Caramelo CA. Mechanisms of the endothelial toxicity of cyclosporin A. Circ Res 1994; 74: 477-484
21. Conde M, Andrate J, Bedoya FJ, Maria Santa C, Sorino F. Inhibitory effect of cyclosporin A and FK506 on nitric oxide production by cultured macrophage, evidence of a direct effect on nitric oxide synthase activity. Immunology 1995; 84: 476-481
22. - cotransport by forskolin and vasopressin in mouse kidney cultured thick ascending limb cells. J Membrane Biol 1994; 142: 323-336
23. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidium thiocynat phenol chloroform extraction. Anal Chem 1987; 162: 156-159
24. 15N]nitrate in biological fluid. Anal Biochem 1982; 126: 131 138
25. Hidaka H, Inagaki M, Kawamoto S, Sasaki Y. Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C. Biochemistry 1984; 23: 5036-5041
26. Riches DWH, Stanworth DR. Primary amines selective release of lysosomal enzymes from mouse macrophages. Biochem J 1980; 188: 933-936
27. Lowry OH, Rosebrough NJ, Farr AL, Kandall JR. Protein measurements with the folin phenol reagent. J Biol Chem 1951; 193: 265-275
28. Southan GJ, Szabó C. Selective pharmacological inhibition of distinct nitric oxide synthase isoforms. Biochem Pharmacol 1996; 51: 383-394
29. Schreiber SL, Crabtree GR. The mechanism of action of cyclosporin A and FK506. Immunology Today 1992; 13: 136-142
30. Kone BC, Schwôbel J, Turner P, Mohaupt MG, Cangro CB. Role of NF-κB in the regulation of inducible nitric oxide synthase in an MTAL cell line. Am J Physiol 1995; 269: F718-F729
31. Biondi ML, Dousa T, Vanhoutte P, Remero JC. Evidences for the existence of endothelium-derived relaxing factor in the renal medulla. Am J Hypertens 1990; 3: 876-878
32. Yang S, Silldroff EP, Pallone TL. Effect of norepinephrine and acetylcholine on outer medullary descending vasa recta. Am J Physiol 1995; 269: H710-H716
33. Lau KS, Nakashima O, Aalund GR, Hogarth L, Ujiie K, Yuen J, Star, RA. TNF-α and IFN-γ induce expression of nitric oxide synthase in cultured rat medullary interstitial cells. Am J Physiol 1995; 269: F212-F217
34. +-ATPase by nitric oxide in mouse tubule epithelial cells. J Clin Invest 1995; 95: 2083-2088
35. Stoos BA, Gracia NH, Garvin JL. Nitric oxide inhibits sodium reabsorption in the isolated perfused cortical collecting duct. J Am Soc Nephrol 1996; 6: 89-94
36. Gracia NH, Stoos BA, Carretero OA, Garvin JL. Mechanism of the nitric oxide-induced blockade of collecting duct water permeability. Hypertension 1996; 27 [part 2]: 679-683
37. + channel in basolateral membrane of cortical collecting duct. Am J Physiol 1996; 270: C1336-C1342
38. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEBJ 1992; 6: 3051-3055
39. Kaplan MR, Plotkin MD, Lee WS, Xu ZC, Lytton J, Hebert SC. Apical localization of Na-K-Cl cotransporter, rBSCl, on rat thick ascending limbs. Kidney Int 1996; 49: 40-47