Transgenic mice overexpressing cyclophilin A are resistant to cyclosporin A-induced nephrotoxicity via peptidyl-prolyl cis-trans isomerase activity

Biochemical and Biophysical Research Communications

Volumn 316, Issue 4, 2004, Pages 1073-1080

  Hong, Feng ^a   Lee, Jinhwa ^b   Piao, Yu Ji ^a   Jae, Yeong Kwon ^a   Kim, Young Joo ^a   Oh, Changkyu ^c   Seo, Jeong Sun ^c   Yun, Yeon Sook ^d   Yang, Chul Woo ^e   Ha, Joohun ^a   Kim, Sung Soo ^a  

^a Kyung Hee University Hospital   (South Korea)

^b Dongseo University   (South Korea)

^c Seoul National University   (South Korea)

^d Korea Institute of Radiation and Medical Science   (South Korea)

^e The Catholic University of Korea   (South Korea)

Author keywords

Catalase; Cyclophilin A; Cyclosporin A induced nephrotoxicity; PPIase activity

Indexed keywords

CYCLOPHILIN; CYCLOPHILIN A; CYCLOSPORIN A;

ANTIBIOTIC RESISTANCE; ARTICLE; CONTROLLED STUDY; DISEASE EXACERBATION; ENZYME ACTIVITY; GENE OVEREXPRESSION; MOUSE; MUTANT; MYOBLAST; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE; WILD TYPE;

ANIMALS; ANTIOXIDANTS; CYCLOPHILIN A; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; KIDNEY; MICE; MICE, TRANSGENIC; PEPTIDYLPROLYL ISOMERASE; RECOMBINANT PROTEINS; SURVIVAL RATE;

ANIMALIA; MUS MUSCULUS;

EID: 12144288671     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.02.160     Document Type: Article

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