Determination of the toxic dose of lidocaine in dogs and its corresponding serum concentration

Veterinary Record

Volumn 160, Issue 11, 2007, Pages 374-375

  Lemo, N ^a   Vnuk, D ^a   Radisic, B ^a   Skender, L ^b   Karacic, V ^b   Brcic, I ^b  

^a UNIVERSITY OF ZAGREB   (Croatia)

^b INSTITUTE FOR MEDICAL RESEARCH AND OCCUPATIONAL HEALTH   (Croatia)

Author keywords

[No Author keywords available]

Indexed keywords

CANIS FAMILIARIS;

EID: 34047134626     PISSN: 00424900     EISSN: None     Source Type: Journal    
DOI: 10.1136/vr.160.11.374     Document Type: Article

References (17)

1. ELIN, R. J., FRIED, M. W., SAMPSON, M., RUDDEL, M., KLEINER, D. E. & DIBISCEGLIE, A. M. (1997) Assessment of monoethylglycinexylidide as measure of liver function for patients with chronic viral hepatitis. Clinical Chemistry 43, 1952-1957
2. HAASIO, J., HEKALI, R. & ROSENBERG, P. H. (1988) Influence of premedication on lignocaine-induced acute toxicity and plasma concentrations of lignocaine. British Journal of Anaesthesia 61, 131-134
3. HALL, L. W., CLARKE, K. W. & TRIM, C. M. (2000a) General principles of local analgesia. In Veterinary Anaesthesia. 10th edn. Eds L. W. Hall, K. W. Clarke, C. M. Trim. London, W. B. Saunders. pp 225-245
4. HALL, L. W., CLARKE, K. W. & TRIM, C. M. (2000b) Anaesthesia of the dog. In Veterinary Anaesthesia. 10th edn. Eds L. W. Hall, K. W. Clarke, C. M. Trim. London, W. B. Saunders. pp 385-439
5. KUSHNER, L. I., FAN, B. & SHOFER, F. S. (2002) Intravenous regional anesthesia in isoflurane anesthetized cats: lidocaine plasma concentrations and cardiovascular effects. Veterinary Anaesthesia and Analgesia 29, 140-147
6. LIU, P., FELDMAN, H., & COVINO, B. M. (1980) Acute cardiovascular toxicity of lidocaine, bupivacaine and etidocaine in anesthetized, ventilated dogs. Anesthesiology 53, 231-234
7. LIU-ALLISON, L. Y., HUI, R. A. & SCHWENZER, K. S. (1997) Analysis of lidocaine on the Cobas INTEGRA. Annals of Clinical and Laboratory Science 27, 105-115
8. LUNNEY, J. & ETTINGER, S. J. (1995) Cardiac arrhythmias. In Textbook of Veterinary Internal Medicine. Vol 1. Eds S. J. Ettinger, E. C. Feldman. Philadelphia, W. B. Saunders. pp 959-995
9. MALONE, E. D., TURNER, T. A. & WILSON, J. H. (1998) Intravenous lidocaine for the treatment of equine ileus. Proceedings of the 6th Equine Colic Research Symposium. Georgia, USA, November 8 to 11, 1998. p 42
10. MANNA, L., BERTOCCHI, P., VALVO, L. & BARDOCCI, A. (2002) Development and validation of a reversed-phase liquid chromatographic method for the assay of lidocaine in aqueous humour samples. Journal of Pharmaceutical and Biomedical Analysis 29, 1121-1126
11. MEYER, G. A., LIN, H. C., HANSON, R. R. & HAYES, T. L. (2001) Effects of intravenous lidocaine overdose on cardiac electrical activity and blood pressure in the horse. Equine Veterinary Journal 33, 434-437
12. NOLAN, A. M. (2000) Pharmacology of analgesic drugs. In Pain Management in Animals. Eds P. A. Flecknell, A. Waterman-Pearson. London, W. B. Saunders. pp 21-52
13. OHSHIMA, T. & TAKAYASU, T. (1999) Simultaneous determination of local anesthetics including ester-type anesthetics in human plasma and urine by gas chromatography-mass spectrometry with solid-phase extraction. Journal of Chromatography B Biomedical Sciences and Applications 726, 185-194
14. SKARDA, R. T. (1998) Local and regional anesthetic and analgesic techniques: dogs. In Veterinary Anesthesia. 3rd edn. Eds J. C. Thurmon, W. J. Tranquilli, G. J. Benson. Baltimore, Williams & Wilkins. pp 426-447
15. STONESTREET, B. S., PATLAUK, C. S., PETTIGREW, K. D., REILLY, C. B. & CSERR, H. F. (1996) Ontogeny of blood-brain barrier function in ovine fetuses, lambs, and adults. American Journal of Physiology 271, R1594-R1601
16. WALLACE, M. S., LAITIN, S., LICHT, D. & YAKSH, T. L. (1997) Concentration-effect relations for intravenous lidocaine infusions in human volunteers: effects on acute sensory thresholds and capsaicin-evoked hyperpathia. Anesthesiology 86, 1262-1272
17. WILCKE, J. R., DAVIS, L. E. & NEFF-DAVIS, C. A. (1983) Determination of lidocaine concentrations producing therapeutic and toxic effects in dogs. Journal of Veterinary Pharmacology and Therapeutics 6, 105-112