Pregnancy-associated glycoprotein family (PAG)-As chorionic signaling ligands for gonadotropin receptors of cyclic animals

Animal Reproduction Science

Volumn 99, Issue 3-4, 2007, Pages 269-284

  Szafranska, B ^a   Panasiewicz, G ^a   Majewska, M ^a   Romanowska, A ^a   Dajnowiec, J ^a  

^a UNIVERSITY OF WARMIA AND MAZURY IN OLSZTYN   (Poland)

Author keywords

Chorionic ligands; Cyclic gilts; Gonadal and extragonadal gonadotropin receptors; Trophoblast trophectoderm

Indexed keywords

LIGAND; LUTEINIZING HORMONE RECEPTOR; PLACENTA PROTEIN;

ANIMAL; ARTICLE; BINDING SITE; CATTLE; CHORION; CORPUS LUTEUM; ESTRUS CYCLE; FEMALE; METABOLISM; PHYSIOLOGY; PLACENTA; PREGNANCY; SIGNAL TRANSDUCTION; SWINE; UTERUS;

ANIMALS; BINDING SITES; CATTLE; CHORION; CORPUS LUTEUM; ESTROUS CYCLE; FEMALE; LIGANDS; PLACENTA; PREGNANCY; PREGNANCY PROTEINS; RECEPTORS, LH; SIGNAL TRANSDUCTION; SWINE; UTERUS;

ANIMALIA; BOS; BOVINAE; EUTHERIA; MAMMALIA; SUIDAE; SUS;

EID: 33947652786     PISSN: 03784320     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anireprosci.2006.05.012     Document Type: Article

References (80)

1. Atkinson Y.H., Gogolin-Ewens K.J., Hounsell E.F., Davies M.J., Brandon M.R., and Seamark R.F. Characterization of placentation-specific binucleate cell glycoproteins possessing a novel carbohydrate. J. Biol. Chem. 268 (1993) 26679-26685
2. Austin K.J., King C.P., Vierk J.E., Sasser R.G., and Hansen T.R. Pregnancy-specific protein B induces release of an alpha chemokine in bovine endometrium. Endocrinology 140 (1999) 542-545
3. Bazer F.W., Ott T.L., and Spencer T.E. Pregnancy recognition in ruminants, pigs and horses: signals from the trophoblast. Theriogenology 41 (1994) 79-94
4. Binelli M., Guzeloglu A., Badinga L., Arnold D.R., Sirois J., Hansen T.R., and Thatcher W.W. Interferon-tau modulates phorbol ester-induced production of prostaglandin and expression of cyclooxygenase-2 and phospholipase-A(2) from bovine endometrial cells. Biol. Reprod. 63 (2000) 417-424
5. 2 secretion by cultured porcine endometrial cells. Reproduction 130 (2005) 105-112
6. Chabot V., Lambert R.D., Laforest J.P., St-Jacques S., Matte J.J., Guay F., Palin M.F., and Lessard M. Effect of oestrous cycle and early pregnancy on uterine production and expression of immune regulatory factors in gilts. Anim. Reprod. Sci. 81 (2004) 137-149
7. Chen X., Rosenfeld C.S., Roberts R.M., and Green J.A. An aspartic proteinase expressed in the yolk sac and neonatal stomach of the mouse. Biol. Reprod. 65 (2001) 1092-1101
8. Del Vecchio R.P. Effect of pregnancy-specific protein B on prostaglandin F2 alpha and prostaglandin E2 release by day 16-perifused bovine endometrial tissue. Prostaglandins 40 (1990) 271-282
9. Del Vecchio R.P., Sutherland W.D., and Sasser R.G. Effect of pregnancy-specific protein B on luteal cell progesterone, prostaglandin, and oxytocin production during two stages of the bovine estrous cycle. J. Anim. Sci. 73 (1995) 2662-2668
10. Del Vecchio R.P., Sutherland W.D., and Sasser R.G. Prostaglandin F2 alpha, progesterone and oxytocin production by cultured bovine luteal cells treated with prostaglandin E2 and pregnancy-specific protein B. Prostaglandins 50 (1995) 137-150
11. Del Vecchio R.P., Sutherland W.D., and Sasser R.G. Bovine luteal cell production in vitro of prostaglandin E2, oxytocin and progesterone in response to pregnancy-specific protein B and prostaglandin F2 alpha. J. Reprod. Fertil. 107 (1996) 131-136
12. Dore, Kattesh H.G., and Godkin J.D. Isolation and identification of porcine embryonic basic protein as a fragment of pregnancy-associated glycoprotein-2. Int. J. Biochem. Cell Biol. 28 (1996) 1249-1255
13. Dosogne H., Massart-Leen A.M., and Bervenich C. Immunological aspects of pregnancy-associated glycoproteins. Adv. Med. Biol. 480 (2000) 295-305
14. Ealy A.D., Larson S.F., Liu L., Alexenko A.P., Winkelman G.L., Kubisch H.M., Bixby J.A., and Roberts R.M. Polymorphic forms of expressed bovine interferon-tau genes: relative transcript abundance during early placental development, promoter sequences of genes and biological activity of protein products. Endocrinology 142 (2001) 2906-2915
15. El Amiri B., Remy B., De Sousa N.M., Joris B., Ottiers N.G., Perenyi Z., Banga-Mboko H., and Beckers J.F. Isolation and partial characterization of three pregnancy-associated glycoproteins from the ewe placenta. Mol. Reprod. Dev. 64 (2003) 199-206
16. El Amiri B., Remy B., De Sousa N.M., and Beckers J.F. Isolation and characterization of eight pregnancy-associated glycoproteins present at high levels in the ovine placenta between day 60 and day 100 of gestation. Reprod. Nutr. Dev. 44 (2004) 169-181
17. Fields M.J., and Shemesh M. Extragonadal luteinizing hormone receptors in the reproductive tract of domestic animals. Biol. Reprod. 71 (2004) 1412-1418
18. Flint A.P.F., Saunders P.T.K., and Ziecik A.J. Blastocyst-endometrium interactions and their significance in embryonic mortality. In: Cole D.L.A., and Foxcroft G.R. (Eds). Control of Pig Reproduction vol. 13 (1982) 253-275
19. Freidman S., Gurevich M., and Shemesh M. Bovine cyclic endometrium contains high-affinity luteinizing hormone/human chorionic gonadotropin binding sites. Biol. Reprod. 52 (1995) 1020-1026
20. Gan X., Xie S., Green J., and Roberts R.M. Identification of transcripts for pregnancy-associated glycoprotein (PAG) in Carnivora and Perissodactyla. Biol. Reprod. 56 (1997) 190 (abstract 431)
21. Garbayo J.M., Remy B., Alabart J.L., Folch J., Wattiez R., Falmagne P., and Beckers J.F. Isolation and partial characterization of a pregnancy-associated glycoprotein family from the goat placenta. Biol. Reprod. 58 (1998) 109-115
22. Garbayo J.M., Green J., Manikkam M., Beckers J.F., Kiesling D.O., Ealy A.D., and Roberts R.M. Caprine pregnancy-associated glycoproteins (PAGs): their cloning, expression and evolutionary relationship to other PAG. Mol. Reprod. Dev. 57 (2000) 311-322
23. Gawronska B., Paukku T., Huhtaniemi I., Wasowicz G., and Ziecik A.J. Oestrogen-dependent expression of LH/hCG receptors in pig Fallopian tube and their role in relaxation of the oviduct. J. Reprod. Fertil. 115 (1999) 293-301
24. Gawronska B., Stepien A., and Ziecik A.J. Effect of estradiol and progesterone on oviductal LH-receptors and LH-dependent relaxation of the porcine oviduct. Theriogenology 53 (2000) 659-672
25. Gebarowska D., Ziecik A.J., and Gregoraszczuk E.L. Luteinizing hormone receptors on granulosa cells from preovulatory follicles and luteal cells throughout the oestrous cycle of pigs. Anim. Reprod. Sci. 49 (1997) 191-205
26. Geisert R.D., and Yelich J.V. Regulation of conceptus development and attachment in pigs. J. Reprod. Fertil. Suppl. 52 (1997) 133-149
27. Georgieva R., Michailova A., Rashev P., and Michova A. Effects of the chromatographic fractions of the pig placental trophoblast on graft-versus-host reaction. Theriogenology 53 (2000) 1705-1715
28. Gonzalez F., Cabrera F., Batista M., Rodriguez N., Alamo D., Sulon J., Beckers J.F., and Gracia A. A comparison of diagnosis of pregnancy in the goat via transrectal ultrasound scanning, progesterone, and pregnancy-associated glycoprotein assays. Theriogenology 62 (2004) 1108-1115
29. Gosh D., and Sengupta J. Recent developments in endocrinology and paracrinology of blastocyst implantation in the primate. Hum. Reprod. Update 4 (1998) 153-168
30. Green J., Xie S., Szafranska B., Newman A., Gan X., McDowell K., and Roberts R.M. Identification of a new aspartic proteinase expressed by the outer chorionic cell layer of the equine placenta. Biol. Reprod. 60 (1999) 1069-1077
31. Green J.A., Xie S., Quan X., Bao B., Gan X., Mathialagan N., Beckers J.F., and Roberts R.M. Pregnancy-associated bovine and ovine glycoproteins exhibit spatially and temporally distinct expression patterns during pregnancy. Biol. Reprod. 62 (2000) 1624-1631
32. Green M.P., Spate L.D., Bixby J.A., Ealy A.D., and Roberts R.M. A comparison of the anti-luteolytic activities of recombinant ovine interferon-alpha and -tau in sheep. Biol. Reprod. 73 (2005) 1087-1093
33. Guruprasad K., Blundell T.L., Xie S., Green J., Szafranska B., Nagel R.J., Mcdowell K., Baker C.B., and Roberts R.M. Comparative modelling and analysis of amino acid substitutions suggests that the family of pregnancy associated glycoproteins includes both active and inactive aspartic proteinases. Protein Eng. 9 10 (1996) 849-856
34. Humblot P. Use of pregnancy specific proteins and progesterone assays to monitor pregnancy and determine the timing, frequencies and sources of embryonic mortality in ruminants. Theriogenology 56 (2001) 1417-1433
35. Johnson G.A., Spencer T.E., Burghardt R.C., Joyce M.M., and Bazer F.W. Interferon-tau and progesterone regulate ubiquitin cross-reactive protein expression in the ovine uterus. Biol. Reprod. 62 (2000) 622-627
36. Loosfelt H., Misrahi M., Atger M., Salesse R., Vu Hai-Luu Thi M.T., Jolivet A., Guiochon-Mantel A., Sar S., Jallal B., Garnier J., and Milgrom E. Cloning and sequencing of porcine LH-hCG receptor cDNA: variants lacking transmembrane domain. Science 245 (1989) 525-528
37. Majewska M., Panasiewicz G., Dabrowski M., Gizejewski Z., Beckers J.F., and Szafranska B. Multiple forms of pregnancy-associated glycoproteins released in vitro by porcine chorion or placentomal and interplacentomal explants of wild and domestic ruminants. Reprod. Biol. 5 (2005) 185-203
38. Panasiewicz G., Majewska M., and Szafranska B. Trophoblastic cDNA cloning of porcine pregnancy-associated glycoprotein genes (pPAG) and in silico analysis of coded polypeptide precursors. Reprod. Biol. 4 (2004) 131-141
39. Panasiewicz G., Majewska M., and Szafranska B. The involvement of luteinizing hormone (LH) and pregnancy-associated glycoprotein family (PAG) in pregnancy maintenance in the pig. Reprod. Biol. 4 (2004) 143-163
40. Roberts R.M., Cross J.C., and Leaman D.W. Interferons as hormones of pregnancy. Endocr. Rev. 13 (1992) 432-452
41. Roberts R.M., Xie S., and Trout W.E. Embryo-uterine interactions in pigs during week 2 of pregnancy. J. Reprod. Fertil. 48 (1993) 171-186
42. Roberts R.M., Xie S., and Mathialagan N. Maternal recognition of pregnancy. Biol. Reprod. 54 (1996) 294-302
43. Shemesh M., Gurevich M., Mizrachi D., Dombrovski L., Stram Y., Fields M.J., and Shore L.S. Expression of functional luteinizing hormone (LH) receptor and its messenger ribonucleic acid in bovine uterine veins: LH induction of cyclooxygenase and augmentation of prostaglandin production in bovine uterine veins. Endocrinology 138 (1997) 4844-4851
44. Shemesh M., Mizrachi D., Gurevich M., Shore L.S., Reed J., Chang S.M., Thatcher W.W., and Fields M.J. Expression of functional luteinizing hormone (LH) receptor and its messenger ribonucleic acid in bovine endometrium: LH augmentation of cAMP and inositol phosphate in vitro and human chorionic gonadotropin (hCG) augmentation of peripheral prostaglandin in vivo. Reprod. Biol. 1 (2001) 13-32
45. Sousa N.M., Remy B., El Amiri B., De Figueiredo J.R., Banga-Mboko H., Dias Goncalves P.B., and Beckers J.F. Characterization of pregnancy-associated glycoproteins extracted from zebu (Bos indicus) placentas removed at different gestational periods. Reprod. Nutr. Dev. 42 (2002) 227-241
46. Spencer T.E., Becker W.C., George P., Mirando M.A., Ogle T.F., and Bazer F.W. Ovine interferon-tau regulates expression of endometrial receptors for estrogen and oxytocin but not progesterone. Biol. Reprod. 53 (1995) 732-745
47. Spencer T.E., Burghardt R.C., Johnson G.A., and Bazer F.W. Conceptus signals for establishment and maintenance of pregnancy. Anim. Reprod. Sci. 82-83 (2004) 537-550
48. Stepien A., Shemesh M., and Ziecik A.J. Luteinising hormone receptor kinetic and LH-induced prostaglandin production throughout the oestrous cycle in porcine endometrium. Reprod. Nutr. Dev. 39 (1999) 663-674
49. Stepien A., Derecka K., Gawronska B., Bodek G., Zwierzchowski L., Shemesh M., and Ziecik A.J. LH/hCG receptors in the porcine uterus-a new evidence of their presence in the cervix. J. Physiol. Pharmacol. 51 (2000) 917-931
50. Szafranska B., and Panasiewicz G. The placental expression of the porcine pregnancy-associated glycoprotein (pPAG) gene family examined in situ and in vitro. Anim. Reprod. Sci. 72 (2002) 95-113
51. Szafranska B., and Tilton J.E. The role of prolactin during mid-pregnancy in the pig. Anim. Reprod. Sci. 261 (1992) 875-877
52. Szafranska B., and Tilton J.E. Prolactin as a luteotrophin during late pregnancy in the pig. J. Reprod. Fertil. 98 (1993) 643-648
53. Szafranska B., and Ziecik A. Active and passive immunization against luteinizing hormone in pigs. Acta Physiol. Hung. 74 (1989) 253-258
54. Szafranska B., and Ziecik A. Effect of bromocriptine administration during mid-pregnancy on the ovary function in the pig. Exp. Clin. Endocrinol. 96 (1990) 317-320
55. Szafranska B., and Ziecik A. Effect of bromocriptine administration on maintenance of late pregnancy in the pig. Exp. Clin. Endocrinol. 96 (1990) 321-324
56. Szafranska B., Xie S., Green J., and Roberts R.M. Porcine pregnancy-associated glycoproteins: new members of the aspartic proteinase gene family expressed in the trophectoderm. Biol. Reprod. 53 (1995) 21-28
57. Szafranska B., Miura R., Ghosh D., Ezashi T., Xie S., Roberts R.M., and Green J. Gene for porcine pregnancy-associated glycoprotein 2 (pPAG2): its structural organization and analysis of its promoter. Mol. Reprod. Dev. 60 (2001) 137-146
58. Szafranska B., Panasiewicz G., and Waclawik A. Length polymorphism of PCR amplified genomic fragments of the pregnancy-associated glycoprotein (PAG) gene family in the pig and some other domestic and wild mammals. J. Appl. Genet. 42 3 (2001) 335-349
59. Szafranska B., Panasiewicz G., Majewska M., and Beckers J.F. Chorionic expression of heterogeneous products of the PAG (pregnancy-associated glycoprotein) gene family secreted in vitro throughout embryonic and foetal development in the pig. Reprod. Nutr. Dev. 43 (2003) 497-516
60. Szafranska B., Majewska M., and Panasiewicz G. N-glycodiversity of the pregnancy-associated glycoprotein family (PAG) produced in vitro by trophoblast and trophectoderm explants during implantation, placentation and advanced pregnancy in the pig. Reprod. Biol. 4 (2004) 67-89
61. Szafranska B., Panasiewicz G., Dabrowski M., Majewska M., Gizejewski Z., and Beckers J.F. Chorionic mRNA expression and N-glycodiversity of pregnancy-associated glycoprotein family (PAG) of the European bison (Bison bonasus). Anim. Reprod. Sci. 88 (2005) 225-243
62. Szenci O., Beckers J.F., Sulon J., Bevers M.M., Borzsonyi L., Fodor L., Kovacs F., and Taverne M.A.M. Effect of induction of late embryonic mortality on plasma profiles of pregnancy associated glycoprotein 1 in heifers. Vet. J. 165 (2003) 307-313
63. Teixeira M.G., Austin K.J., Perry D.J., Dooley V.D., Johnson G.A., Francis B.R., and Hansen T.R. Bovine granulocyte chemotactic protein-2 is secreted by the endometrium in response to interferon-tau (IFN-tau). Endocrine 6 (1997) 31-37
64. Vawter G.A., Parks T.E., Killian G., Ealy A.D., and Green J.A. Cloning and preliminary characterization of pregnancy-associated glycoproteins expressed in the placenta of white-tailed deer. Biol. Reprod. 70 (2004) 153 (abstract 261)
65. Waclawik A., Rivero-Muller A., Blitek A., Kaczmarek M.M., Brokken L.J., Watanabe K., Rahman N.A., and Ziecik A.J. Molecular cloning and spatiotemporal expression of prostaglandin F synthase and microsomal prostaglandin E synthase-1 in porcine endometrium. Endocrinology 147 (2006) 210-221
66. Ward D.N., Liu W.-K., Glenn S.D., and Channing C.P. LH-binding Inhibitors from the Corpus Luteum. Intraovarian Control Mechanisms (1982), Plenum Publishing Corporation pp. 263-281
67. Wasowicz G., Derecka K., Stepien A., Pelliniemi L., Doboszynska T., Gawronska B., and Ziecik A.J. Evidence for the presence of luteinizing hormone-chorionic gonadotrophin receptors in the pig umbilical cord. J. Reprod. Fertil. 117 (1999) 1-9
68. Weems Y.S., Lammoglia M.A., Vera-Avila H.R., Randel R.D., King C., Sasser R.G., and Weems C.W. Effect of luteinizing hormone (LH), PGE2, 8-EPI-PGE1, 8-EPI-PGE2, trichosanthin, and pregnancy specific protein B (PSPB) on secretion of progesterone in vitro by corpora lutea (CL) from nonpregnant and pregnant cows. Prostaglandins Other Lipid Mediat. 55 (1998) 27-42
69. 2α) and progesterone in vitro. Prostaglandins Other Lipid Mediat. 71 (2003) 55-73
70. Wooding F.B.P., Roberts R.M., and Green J.A. Light and electron microscope immunocytochemical studies of the distribution of pregnancy associated glycoproteins (PAGs) throughout pregnancy in the cow: possible functional implications. Placenta 26 (2005) 807-827
71. Xie S., Green J., Bao B., Beckers J.F., Valdez K.E., Hakami L., and Roberts R.M. Multiple pregnancy-associated glycoproteins are secreted by day 100 ovine placental tissue. Biol. Reprod. 57 (1997) 1384-1393
72. Xie S., Green J., Bixby J.B., Szafranska B., Demartini J.C., Hecht S., and Roberts R.M. The diversity and evolutionary relationships of the pregnancy-associated glycoproteins, an aspartic proteinase subfamily consisting of many trophoblast-expressed genes. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 12809-12816
73. 90 of the α-subunit are crucial for receptor binding and hormone action of follicle-stimulating hormone (FSH) and play hormone-specific roles in FSH and human chorionic gonadotropin. Endocrinology 136 (1995) 2498-2953
74. Ziecik J.A. Old, new and the newest concepts of inhibition of luteolysis during early pregnancy in pig. Domest. Anim. Endocrinol. 23 1-2 (2002) 265-275
75. Ziecik A., Shaw H.J., and Flint A.P. Luteal LH receptors during the oestrous cycle and early pregnancy in the pig. J. Reprod. Fertil. 60 (1980) 129-137
76. Ziecik A.J., Stanchev P.D., and Tilton J.E. Evidence for the presence of luteinizing hormone/human chorionic gonadotropin-binding sites in the porcine uterus. Endocrinology 119 (1986) 1159-1163
77. Ziecik A.J., Derecka-Reszka K., and Rzucidlo S.J. Extragonadal gonadotropin receptors, their distribution and function. J. Physiol. Pharmacol. 43 (1992) 33-49
78. Ziecik A.J., Jedlinska M., and Rzucidlo S.J. Effect of estradiol and progesterone on myometrial LH/hCG receptors in pigs. Acta Endocrinol. (Copenh) 127 (1992) 185-188
79. Ziecik A.J., Ostrowska G., Kisielewska J., and Zezula-Szpyra A. Distribution and cycle phase dependency of gonadotropin receptors in musculature and blood vessels of the porcine broad ligament. Exp. Clin. Endocrinol. Diab. 103 (1995) 44-51
80. Zoli A.P., Beckers J.F., Woutters-Ballman P., Falmagne P., and Ectors F. Purification and characterization of a bovine pregnancy-associated glycoprotein. Biol. Reprod. 45 (1991) 1-10