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Volumn 11, Issue 4, 2007, Pages 427-430

Telomerase inhibition as an adjuvant anticancer therapy: It is more than just a waiting game

Author keywords

Adjuvant therapy; Alternative lengthening of telomeres; Cancer; Chemotherapy; Telomerase; Telomere

Indexed keywords

CYTOTOXIC AGENT; TELOMERASE; TELOMERASE INHIBITOR; TELOMERASE REVERSE TRANSCRIPTASE;

EID: 33947643146     PISSN: 14728222     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728222.11.4.427     Document Type: Editorial
Times cited : (4)

References (16)
  • 1
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • KIM NW, PIATYSZEK MA, PROWSE KR et al: Specific association of human telomerase activity with immortal cells and cancer. Science (1994) 266:2011-2015.
    • (1994) Science , vol.266 , pp. 2011-2015
    • Kim, N.W.1    Piatyszek, M.A.2    Prowse, K.R.3
  • 2
    • 0031010342 scopus 로고    scopus 로고
    • A survey of telomerase activity in human cancer
    • SHAY JW, BACCHETTI S: A survey of telomerase activity in human cancer. Science (1997) 33:787-791.
    • (1997) Science , vol.33 , pp. 787-791
    • Shay, J.W.1    Bacchetti, S.2
  • 3
  • 4
    • 20444371017 scopus 로고    scopus 로고
    • The telomerase reverse transcriptase regulates chromatin state and DNA damage response
    • MASUTOMI K, POSSEMATO R, WONG JM et al: The telomerase reverse transcriptase regulates chromatin state and DNA damage response. Proc. Natl. Acad. Sci. USA (2005) 102(23):8222-8227.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , Issue.23 , pp. 8222-8227
    • Masutomi, K.1    Possemato, R.2    Wong, J.M.3
  • 5
    • 0043199578 scopus 로고    scopus 로고
    • Telomerase maintains telomere structure in normal human cells
    • MASUTOMI K, YU EY, KHURTS S et al: Telomerase maintains telomere structure in normal human cells. Cell (2002) 114:241-253.
    • (2002) Cell , vol.114 , pp. 241-253
    • Masutomi, K.1    Yu, E.Y.2    Khurts, S.3
  • 6
    • 33846051057 scopus 로고    scopus 로고
    • The molecular basis of ageing in stem cells
    • TAM W-L, ANG Y-S, LIM B: The molecular basis of ageing in stem cells. Mech. Ageing. Dev. (2007) 128:137-148.
    • (2007) Mech. Ageing. Dev. , vol.128 , pp. 137-148
    • Tam, W.-L.1    Ang, Y.-S.2    Lim, B.3
  • 7
    • 10344229954 scopus 로고    scopus 로고
    • Accelerated telomere shortening in response to life stress
    • EPEL ES, BLACKBURN EH, LIN J et al: Accelerated telomere shortening in response to life stress. Proc. Natl. Acad. Sci. USA (2004) 101(49):17312-17315.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , Issue.49 , pp. 17312-17315
    • Epel, E.S.1    Blackburn, E.H.2    Lin, J.3
  • 8
    • 0025743438 scopus 로고
    • Telomerase primer specificity and chromosome healing
    • HARRINGTON LA, GREIDER CW: Telomerase primer specificity and chromosome healing. Nature (1991) 353:451-454.
    • (1991) Nature , vol.353 , pp. 451-454
    • Harrington, L.A.1    Greider, C.W.2
  • 9
    • 0026037255 scopus 로고
    • Developmentally programmed healing of chromosomes by telomerase in Tetrahymena
    • YU G-L, BLACKBURN EH: Developmentally programmed healing of chromosomes by telomerase in Tetrahymena. Cell (1991) 67:823-832.
    • (1991) Cell , vol.67 , pp. 823-832
    • Yu, G.-L.1    Blackburn, E.H.2
  • 10
    • 0037082423 scopus 로고    scopus 로고
    • Summary and Survey: Natural and pharmacologic regulation of telomerase
    • MERGNY J-L, RIOU J-F, MAILLIET P et al: Summary and Survey: Natural and pharmacologic regulation of telomerase. Nuclei Acids Res. (2002) 30(4):839-865.
    • (2002) Nuclei Acids Res. , vol.30 , Issue.4 , pp. 839-865
    • Mergny, J.-L.1    Riou, J.-F.2    Mailliet, P.3
  • 11
    • 33748316825 scopus 로고    scopus 로고
    • Telomeres inhibition enhances the response to anti-cancer drug treatment in human breast cancer cells
    • CERONE MA, LONDONO-VALLEJO JA, AUTEXIER C: Telomeres inhibition enhances the response to anti-cancer drug treatment in human breast cancer cells. Mol. Cancer Ther. (2006) 5(7):1669-1675.
    • (2006) Mol. Cancer Ther. , vol.5 , Issue.7 , pp. 1669-1675
    • Cerone, M.A.1    Londono-vallejo, J.A.2    Autexier, C.3
  • 12
    • 33845231392 scopus 로고    scopus 로고
    • Mutated telomeres sensitize tumor cells to anti-cancer drugs independent of telomere shortening and mechanisms of telomere maintenance
    • CERONE MA, LONDONO-VALLEJO JA, AUTEXIER C: Mutated telomeres sensitize tumor cells to anti-cancer drugs independent of telomere shortening and mechanisms of telomere maintenance. Oncogene (2006) 25(56):7411-7420.
    • (2006) Oncogene , vol.25 , Issue.56 , pp. 7411-7420
    • Cerone, M.A.1    Londono-vallejo, J.A.2    Autexier, C.3
  • 13
    • 0033568462 scopus 로고    scopus 로고
    • Telomere shortening and apoptosis in telomerase-inhibited human tumor cells
    • ZHANG XL, MAR V, ZHOU W, HARRINGTON, L, ROBINSON MA: Telomere shortening and apoptosis in telomerase-inhibited human tumor cells. Genes Dev. (1999) 13:2388-2399.
    • (1999) Genes Dev. , vol.13 , pp. 2388-2399
    • Zhang, X.L.1    Mar, V.2    Zhou, W.3    Harrington, L.4    Robinson, M.A.5
  • 14
    • 2442659384 scopus 로고    scopus 로고
    • Telomeric recombination in mismatch repair deficient colon cancer cells after telomere inhibition
    • BECHTER OE, ZOU Y, WALKER W, WRIGHT WE, SHAY JW: Telomeric recombination in mismatch repair deficient colon cancer cells after telomere inhibition. Cancer Res. (2004) 64(10):3444-3451.
    • (2004) Cancer Res. , vol.64 , Issue.10 , pp. 3444-3451
    • Bechter, O.E.1    Zou, Y.2    Walker, W.3    Wright, W.E.4    Shay, J.W.5
  • 15
    • 0037224923 scopus 로고    scopus 로고
    • Telomere-based crisis: Functional differences between telomerase activation and ALT in tumor progression
    • CHANG S, KHOO CM, NAYLOR ML, MASER RS, DEPINHO RA: Telomere-based crisis: functional differences between telomerase activation and ALT in tumor progression. Genes Dev. (2003) 17:88-100.
    • (2003) Genes Dev. , vol.17 , pp. 88-100
    • Chang, S.1    Khoo, C.M.2    Naylor, M.L.3    Maser, R.S.4    Depinho, R.A.5
  • 16
    • 0033455559 scopus 로고    scopus 로고
    • Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death
    • HERBERT BS, PITTS AE, BAKER SI et al: Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death. Proc. Natl. Acad. Sci. USA (1999) 96:14276-14281.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 14276-14281
    • Herbert, B.S.1    Pitts, A.E.2    Baker, S.I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.