Polymeric meshes induce zonal regulation of matrix metalloproteinase-2 gene expression by macrophages and fibroblasts

FASEB Journal

Volumn 21, Issue 4, 2007, Pages 1047-1057

  Jansen, Petra Lynen ^a,b   Kever, Mona ^b   Rosch, Raphael ^b   Krott, Ellen ^b   Jansen, Marc ^b   Alfonso Jaume, Alexandra ^c   Dooley, Steven ^d   Klinge, Uwe ^b   Lovett, David H ^e   Mertens, Peter R ^b  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d UNIVERSITY OF HEIDELBERG   (Germany)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cell specific gene regulation; Polymers; Transgene; Wound healing

Indexed keywords

GELATINASE A; POLYGLACTIN; POLYPROPYLENE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; FIBROBLAST; FIBROSIS; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; IMPLANTATION; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; UPREGULATION; WOUND HEALING;

ANIMALS; BIOCOMPATIBLE MATERIALS; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GRANULOMA; MACROPHAGES; MALE; MATRIX METALLOPROTEINASE 2; MICE; MICE, TRANSGENIC; NIH 3T3 CELLS; POLYMERS; PROMOTER REGIONS (GENETICS); TRANSCRIPTION, GENETIC; WOUND HEALING;

MUS;

EID: 33947615143     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.06-6755com     Document Type: Article

References (49)

1. Jansen, P. L., Mertens, P. P., Klinge, U., and Schumpelick, V. (2004) The biology of hernia formation. Surgery 136, 1-4
2. Junge, K., Klinge, U., Rosch, R., Mertens, P. R., Kirch, J., Klosterhalfen, B., Lynen, P., and Schumpelick, V. (2004) Decreased collagen type I/III ratio in patients with recurring hernia after implantation of alloplastic prostheses. Langenbecks Arch. Surg. 389, 17-22
3. Klinge, U., Schumpelick, V., and Klosterhalfen, B. (2001) Functional assessment and tissue response of short- and long-term absorbable surgical meshes. Biomaterials 22, 1415-1424
4. Klinge, U., Klosterhalfen, B., Muller, M., Anurov, M., Ottinger, A., and Schumpelick, V. (1999) Influence of polyglactin-coating on functional and morphological parameters of polypropylene-mesh modifications for abdominal wall repair. Biomaterials 20, 613-623
5. Baum, C. L., and Arpey, C. J. (2005) Normal cutaneous wound healing: clinical correlation with cellular and molecular events. Dermatol. Surg. 31, 674-686
6. Chapman, H. A. (2004) Disorders of lung matrix remodeling. J. Clin. Invest. 113, 148-157
7. Woessner, J. F., Jr. (2002) MMPs and TIMPs - an historical perspective. Mol. Biotechnol. 22, 33-49
8. Kuzuya, M., Iguchi, A. (2003) Role of matrix metalloproteinases in vascular remodeling. J. Atheroscler. Thromb. 10, 275-282
9. Kato, T., Kure, T., Chang, J. H., Gabison, E. E., Itoh, T., Itohara, S., and Azar, D. T. (2001) Diminished corneal angiogenesis in gelatinase A-deficient mice. FEBS Lett. 508, 187-190
10. Ishikawa, T., Nishigaki, F., Miyata, S., Hirayama, Y., Minoura, K., Imanishi, J., Neya, M., Mizutani, T., Imamura, Y., Naritomi, Y., Murai, H., Ohkubo, Y., Kagayama, A., and Mutoh, S. (2005) Prevention of progressive joint destruction in collagen-induced arthritis in rats by a novel matrix metalloproteinase inhibitor, FR255031. Br. J. Pharmacol. 144, 133-143
11. Mandal, M., Mandal, A., Das, S., Chakraborti, T., and Chakraborti, S. (2003) Clinical implications of matrix metalloproteinases. Mol. Cell. Biochem. 252, 305-329
12. Wu, M., and Li, Y. G. (2006) The expression of CD40-CD40L and activities of matrix metalloproteinases in atherosclerotic rats. Mol. Cell Biochem. 282, 141-146
13. Agren, M. S. (1994) Gelatinase activity during wound healing. Br. J. Dermatol. 131, 634-640
14. Turck, J., Pollock, A. S., Lee, L. K., Marti, H. P., and Lovett, D. H. (1996) Matrix metalloproteinase 2 (gelatinase A) regulates glomerular mesangial cell proliferation and differentiation. J. Biol. Chem. 271, 15074-15083
15. Marti, H. P., Lee, L., Kashgarian, M., and Lovett, D. H. (1994) Transforming growth factor-beta 1 stimulates glomerular mesangial cell synthesis of the 72-kd type IV collagenase. Am. J. Pathol. 144, 82-94
16. Olaso, E., Labrador, J. P., Wang, L., Ikeda, K., Eng, F. J., Klein, R., Lovett, D. H., Lin, H. C., and Friedman, S. L. (2002) Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2. J. Biol. Chem. 277, 3606-3613
17. Cheng, S., and Lovett, D. H. (2003) Gelatinase A (MMP-2) is necessary and sufficient for renal tubular cell epithelial-mesenchymal transformation. Am. J. Pathol. 162, 1937-1949
18. Witte, M. B., Thornton, F. J., Kiyama, T., Efron, D. T., Schulz, G. S., Moldawer, L. L., and Barbul, A. (1998) Metalloproteinase inhibitors and wound healing: a novel enhancer of wound strength. Surgery 124, 464-470
19. Matsumura, S., Iwanaga, S., Mochizuki, S., Okamoto, H., Ogawa, S., and Okada, Y. (2005) Targeted deletion or pharmacological inhibition of MMP-2 prevents cardiac rupture after myocardial infarction in mice. J. Clin. Invest. 115, 599-609
20. Bellon, J. M., Bajo, A., Ga-Honduvilla, N., Gimeno, M. J., Pascual, G., Guerrero, A., and Bujan, J. (2001) Fibroblasts from the transversalis fascia of young patients with direct inguinal hernias show constitutive MMP-2 overexpression. Ann. Surg. 233, 287-291
21. Overall, C. M., and Lopez-Otin, C. (2002) Strategies for MMP inhibition in cancer: innovations for the post-trial era. Nat. Rev. Cancer 2, 657-672
22. Chakraborti, S., Mandal, M., Das, S., Mandal, A., Chakraborti, T. (2003) Regulation of matrix metalloproteinases: An overview. Mol. Cell. Biochem. 253, 269-285
23. Kleiner, D. E., Jr., and Stetler-Stevenson, W. G. (1993) Structural biochemistry and activation of matrix metalloproteases. Curr. Opin. Cell Biol. 5, 891-897
24. Harendza, S., Pollock, A. S., Mertens, P. R., and Lovett, D. H. (1995) Tissue-specific enhancer-promoter interactions regulate high level constitutive expression of matrix metalloproteinase 2 by glomerular mesangial cells. J. Biol. Chem. 270, 18786-18796
25. Marti, H. P., McNeil, L., Davies, M., Martin, J., and Lovett, D. H. (1993) Homology cloning of rat 72 kDa type IV collagenase: cytokine and second-messenger inducibility in glomerular mesangial cells. Biochem. J. 291(Pt 2), 441-446
26. Overall, C. M., Wrana, J. L., and Sodek, J. (1989) Independent regulation of collagenase, 72-kDa progelatinase, and metalloendoproteinase inhibitor expression in human fibroblasts by transforming growth factor-beta. J. Biol. Chem. 264, 1860-1869
27. Baker, A. H., Edwards, D. R., Murphy, G. (2002) Metalloproteinase inhibitors: biological actions and therapeutic opportunities. J. Cell Sci. 115, 3719-3727
28. Morgunova, E., Tuuttila, A., Bergmann, U., Isupov, M., Lindqvist, Y., Schneider, G., and Tryggvason, K. (1999) Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed. Science 284, 1667-1670
29. Frisch, S. M., and Morisaki, J. H. (1990) Positive and negative transcriptional elements of the human type IV collagenase gene. Mol. Cell. Biol. 10, 6524-6532
30. Harendza, S., Lovett, D. H., and Stahl, R. A. K. (2000) The hematopoietic transcription factor PU. 1 represses gelatinase A transcription in glomerular mesangial cells. J. Biol. Chem. 275, 19552-19559
31. Mertens, P. R., Steinmann, K., Alfonso-Jaume, M. A., En-Nia, A., Sun, Y., Lovett, D. H. (2002) Combinatorial interactions of p53, AP2 and YB-1 with a single enhancer element regulate gelatinase A expression in neoplastic cells. J. Biol. Chem. 277, 24875-24882
32. Mertens, P. R., Harendza, S., Pollock, A. S., Lovett, D. H. (1997) Glomerular mesangial cell-specific transactivation of matrix metalloproteinase 2 A transcription is mediated by YB-1. J. Biol. Chem. 272, 22905-22912
33. Mertens, P. R., Alfonso-Jaume, M. A., Steinmann, K., Lovett, D. H. (1998) A synergistic interaction of transcription factors AP2 and YB-1 regulates gelatinase A enhancer-dependent transcription. J. Biol. Chem. 273, 32957-32965
34. Mertens, P. R., Alfonso-Jaume, M. A., Steinmann, K., and Lovett, D. H. (1999) YB-1 regulation of the human and rat gelatinase A genes via similar enhancer elements. J. Am. Soc. Nephrol. 10, 2480-2487
35. Cheng, S., Alfonso-Jaume, M. A., Mertens, P. R., and Lovett, D. H. (2002) Tumour metastasis suppressor, nm23-beta, inhibits gelatinase A transcription by interference with transactivator Y-box protein-1 (YB-1). Biochem. J. 366, 807-816
36. En-Nia, A., Reisdorff, J., Stefanidis, I., Floege, J., Heinrich, P. C., and Mertens, P. R. (2002) Mesangial cell gelatinase A synthesis is attenuated by oscillating hyperbaric pressure. Biochem. J. 362, 693-700
37. Lee, J. G., Dahi, S., Mahimkar, R., Tulloch, N. L., Alfonso-Jaume, M. A., Lovett, D. H., and Sarkar, R. (2005) Intronic regulation of matrix metalloproteinase-2 revealed by in vivo transcriptional analysis in ischemia. Proc. Natl. Acad. Sci. U. S. A. 102, 16345-16350
38. Klinge, U., Klosterhalfen, B., Muller, M., and Schumpelick, V. (1999) Foreign body reaction to meshes used for the repair of abdominal wall hernias. Eur. J. Surg. 165, 665-673
39. Junge, K., Klinge, U., Rosch, R., Klosterhalfen, B., and Schumpelick, V. (2002) Functional and morphologic properties of a modified mesh for inguinal hernia repair. World J. Surg. 26, 1472-1480
40. Corcoran, M. L., Hewitt, R. E., Kleiner, D. E., Jr., and Stetler-Stevenson, W. G. (1996) MMP-2: expression, activation and inhibition. Enzyme Prot. 49, 7-19
41. Dooley, S., Said, H. M., Gressner, A. M., Floege, J., En-Nia, A., and Mertens, P. R. (2006) Y-box protein-1 is the crucial mediator of antifibrotic interferon-gamma effects. J. Biol. Chem. 281, 1784-1795
42. Ziats, N. P., Miller, K. M., and Anderson, J. M. (1988) In vitro and in vivo interactions of cells with biomaterials. Biomaterials 9, 5-13
43. Lasham, A., Moloney, S., Hale, T., Homer, C., Zhang, Y. F., Murison, J. G., Braithwaite, A. W., and Watson, J. (2003) The Y-box-binding protein, YB1, is a potential negative regulator of the p53 tumor suppressor. J. Biol. Chem. 278, 35516-35523
44. Zhu, P., Ding, J., Zhou, J., Dong, W. J., Fan, C. M., and Chen, Z. N. (2005) Expression of CD147 on monocytes/macrophages in rheumatoid arthritis: its potential role in monocyte accumulation and matrix metalloproteinase production. Arthrit. Res. Ther. 7, R1023-R1033
45. Eerola, L. M., Alho, H. S., Maasilta, P. K., Inkinen, K. A., Harjula, A. L., Litmanen, S. H., and Salminen, U. S. (2005) Matrix metalloproteinase induction in post-transplant obliterative bronchiolitis. J. Heart Lung Transpl. 24, 426-432
46. Brinckerhoff, C. E., and Matrisian, L. M. (2002) Matrix metalloproteinases: a tail of a frog that became a prince. Nat. Rev. Mol. Cell. Biol. 3, 207-214
47. Okada, A., Bellocq, J., Rouyer, N., Chenard, M., Rio, M., Chambon, P., and Basset, P. (1995) Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas. Proc. Natl. Acad. Sci. U. S. A. 92, 2730-2734
48. Chellat, F., Grandjean-Laquerriere, A., Le Naour, R., Fernandes, J., Yahia, L., Guenounou, M., and Laurent-Maquin, D. (2005) Metalloproteinase and cytokine production by THP-1 macrophages following exposure to chitosan-DNA nanoparticles. Biomaterials 26, 961-970
49. Inagaki, Y., Kushida, M., Higashi, K., Itoh, J., Higashiyama, R., Hong, Y. Y., Kawada, N., Namikawa, K., Kiyama, H., Bou-Gharios, G., et al. (2005) Cell type-specific intervention of transforming growth factor beta/Smad signaling suppresses collagen gene expression and hepatic fibrosis in mice. Gastroenterology 129, 259-268