YB-1 regulation of the human and rat gelatinase A genes via similar enhancer elements

Journal of the American Society of Nephrology

Volumn 10, Issue 12, 1999, Pages 2480-2487

  Mertens, Peter R ^b   Alfonso Jaume, Maria Alexandra ^a   Steinmann, Karin ^a   Lovett, David H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; MATRIX METALLOPROTEINASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR AP 2;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA FLANKING REGION; ENHANCER REGION; GENE EXPRESSION REGULATION; GENE SEQUENCE; GLOMERULOSCLEROSIS; HUMAN; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; RAT; SEQUENCE HOMOLOGY; TRANSACTIVATION; TRANSCRIPTION REGULATION;

EID: 0032727263     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Floege J, Burns MW, Alpers CE, Yoshimura A, Pritzl P, Gordon K, Seifert RA, Bowen-Pope DF, Couser WG, Johnson RJ: Glomerular cell proliferation and PDGF expression precede glomerulosclerosis in the remnant kidney model. Kidney Int 41: 297-309, 1992
2. Harendza S, Behrens U, Zahner G, Schneider A, Stahl RA: In vitro characterization of the mesangial phenotype in a proliferative glomerulonephritis of the rat. Nephrol Dial Transplant 12: 2537-2541, 1997
3. Rupprecht HD, Schocklmann HO, Sterzel RB: Cell-matrix interactions in the glomerular mesangium. Kidney Int 49: 1575-1582, 1996
4. Lovett DH, Johnson RJ, Marti H-P, Martin J, Davies M, Couser WG: Structural characterization of the mesangial cell type IV collagenase and enhanced expression in a model of immune-mediated glomerulonephritis. Am J Pathol 141: 85-98, 1992
5. Turck J, Pollock AS, Lee LK, Marti H-P, Lovett DH: Matrix metalloproteinase 2 (gelatinase A) regulates glomerular mesangial cell proliferation and differentiation. J Biol Chem 271: 15074-15083, 1996
6. Turck J, Pollock AS, Lovett DH: Gelatinase A is a glomerular mesangial cell growth and differentiation factor. Kidney Int 51: 1397-1400, 1997
7. Martin J, Knowlden J, Davies M, Williams JD: Identification and independent regulation of human mesangial cell metalloproteinases. Kidney Int 46: 877-885, 1994
8. Del Prete D, Anglani F, Forino M, Ceol M, Fioretto P, Baggio B, Gambaro G: Down-regulation of glomerular matrix metalloproteinase-2 gene in human NIDDM. Diabetologia 40: 1449-1454, 1997
9. Mertens PR, Harendza S, Pollock AS, Lovett DH: Glomerular mesangial cell-specific transactivation of matrix metalloproteinase 2 transcription is mediated by YB-1. J Biol Chem 272: 22905-22912, 1997
10. Mertens PR, Jaume A, Steinmann K, Lovett DH: A synergistic interaction of transcription factors AP2 and YB-1 regulates gelatinase A enhancer-dependent transcription. J Biol Chem 273: 32957-32965, 1998
11. Frisch SM, Morisaki JH: Positive and negative transcriptional elements of the human type IV collagenase gene. Mol Cell Biol 10: 6524-6532, 1990
12. Somasundaram K, Jayaraman G, Williams T, Moran E, Frisch S, Thimmapaya B: Repression of a matrix metalloprotease gene by E1A correlates with its ability to bind to cell type-specific transcription factor AP2. Proc Natl Acad Sci USA 93: 3088-3093, 1996
13. Mac-Donald GH, Itoh-Lindstrom Y, Ting JP-Y: The transcriptional regulatory protein, YB-1, promotes single-stranded regions in the DRA promoter. J Biol Chem 270: 3527-3533, 1995
14. Harendza S, Pollock AS, Mertens PR, Lovett DH: Tissue-specific enhancer-promoter interactions regulate high level constitutive expression of matrix metalloproteinase 2 by glomerular mesangial cells. J Biol Chem 270: 18786-18796, 1995
15. Rosenthal N: Identification of regulatory elements of cloned genes with functional assays. Methods Enzymol 152: 704-720, 1987
16. Brasier AR, Tate JE, Habener JF: Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines. BioTechniques 7: 1116-1122, 1989
17. Kolluri R, Torrey TA, Kinniburgh AJ: A CT promoter element binding protein: Definition of a double-strand and a novel single-strand DNA binding motif. Nucleic Acids Res 20: 111-116, 1992
18. Grant CE, Deeley RG: Cloning and characterization of chicken YB-1: Regulation of expression in the liver. Mol Cell Biol 13: 4186-4196, 1993